MESO-Rx Exclusive Trenbolone facts - series on unique characteristics of different steroids

[Type-IIx]

It's not universally true. Your experience is very cool, but that's not what most people report. What you describe is not what I experienced, and not what the person I was replying to seems to have experienced. Did Reta affect appetite? Sure, I was a little less interested in food. "I could eat, or not, whatever." With Tirz it felt like "There is no fucking way I'm touching that food."

There's a reason people are buying Cagri, and why Chase Irons is selling a Reta/Cagri stack. Enough people don't experience significant appetite suppression on Reta alone that there's a market for an "upgrade".

Everybody's got a different response to every drug, YMMV, et cetera. Some people have paradoxical reactions to drugs completely opposite to what the majority experience.

The Reta study showed greater % body weight loss on average than Sema or Tirz, so clearly it works for large populations regardless of appetite control potential. But it may be that there are people with eating patterns so disordered that it's not the best fit for them. Hell, his binge eating may be so deeply wired that no appetite suppressant will help because it's not appetite driven. I don't know, I'm just a dog on the internet.

This is all true but so is the statement that per-mg and per-$, semaglutide is more potent at suppressing appetite than tirzepatide, retatrutide, and cagrilinitide.

Those drugs are better for blood glucose management.

Of course, still, exceptions exist because of individual drug response. We’re not talking basic math here, unlike HOMA-IR, and why you don’t need to get it calculated to calculate it yourself

 

[explodingHeart]

Can people even still buy tren outside of India pharma?

 

[Deadpool99]

Hey guys,
Does anyone experience fatigue or laziness during tren, first 6-8 weeks I was energetic AF even on an aggressive cut. Creeping up to my 14th and final week and for the past few weeks I’ve been feeling a shit ton fatigue and low energy so I was curious if it was the tren. It doesn’t affect my sleep that much but I feel like the way it affects dopamine it might be the issue for me.

 

[ToesOverKnees]

Hey guys,
Does anyone experience fatigue or laziness during tren, first 6-8 weeks I was energetic AF even on an aggressive cut. Creeping up to my 14th and final week and for the past few weeks I’ve been feeling a shit ton fatigue and low energy so I was curious if it was the tren. It doesn’t affect my sleep that much but I feel like the way it affects dopamine it might be the issue for me.

Are your actuality tracking your sleep? Heart rate over night, movement during the night and an audio recorder app to see if you're snoring?

 

[Deadpool99]

Are your actuality tracking your sleep? Heart rate over night, movement during the night and an audio recorder app to see if you're snoring?

Heart rate no, but I do have a high rhr, around the high 80’s, I do wake up a few times during the night due to night sweats, I just wake up and move to the other side of the bed. I snore occasionally depending on my sleep position.

 

[Deadpool99]

Are your actuality tracking your sleep? Heart rate over night, movement during the night and an audio recorder app to see if you're snoring?

If sleep is the main cause of my fatigue, is there a way to fix it?

 

[b6798045]

@Type-IIx Do low doses of trenbolone (e.g., 10 mg/day) stimulate the upregulation of IGF-1 isoforms in skeletal muscle, and is this effect dose-dependent in a linear manner?

 

[VStar]

Tren E @ 200mg/ml
140mg p/w pinning 0.1ml (20mg) ED. Appetite is stable but stable is eating more than average so 6 meals shakes etc. Whether it's ace or e, I'm a ED person. Tren is potent and this low dose, for me anyhow is a stable dose for my BI size weight etc.
I've gone lower 0.05ml (10mg), but I'm pulling tren first so take it to 0.05 on the syringe and yes I inject with 0.5 bubble space. But basically it's what im saying is it's important and im just realizing this also, on how potent Tren is and how little you need. I notice the body also goes through "bursts" of growth unrelated to dosages or any "blast".

 

[Jleist007]

I dont see any studies that say Trenbolone by itself decreases GH

 

[AlexDavis43]

I dont see any studies that say Trenbolone by itself decreases GH

It would be IGF1, not GH, but I don't know where on the spectrum of bro-science that falls on

Some studies show tren increases IGF1 or signaling at the IGF1 receptor

 

[TTren]

Hey guys,
Does anyone experience fatigue or laziness during tren, first 6-8 weeks I was energetic AF even on an aggressive cut. Creeping up to my 14th and final week and for the past few weeks I’ve been feeling a shit ton fatigue and low energy so I was curious if it was the tren. It doesn’t affect my sleep that much but I feel like the way it affects dopamine it might be the issue for me.

it means ur body needs a break or at the least lower the dose

 

[dinfar1337]

It would be IGF1, not GH, but I don't know where on the spectrum of bro-science that falls on

we have lower igf-1 because tren supresses hgh signaling in the liver.

while this is what we've got from animal studies.

you will have lower igf-1 levels in plasma(systemically) but tren will upregulate igf-1 gene expression locally in muscle tissue.

the data from studies are a little different from animal to animal

but the numbers are somewhat from along the lines what i remember:

liver igf-1 -45%

muscle igf-1 mRNA +300%

this is in different animals from cattle to sheep. no reliable human trials.

that goes to say, drop the big hgh dose on tren and just use a little dose for fat loss

 

[AlexDavis43]

we have lower igf-1 because tren supresses hgh signaling in the liver.

while this is what we've got from animal studies.

you will have lower igf-1 levels in plasma(systemically) but tren will upregulate igf-1 gene expression locally in muscle tissue.

the data from studies are a little different from animal to animal

but the numbers are somewhat from along the lines what i remember:

liver igf-1 -45%

muscle igf-1 mRNA +300%

this is in different animals from cattle to sheep. no reliable human trials.

that goes to say, drop the big hgh dose on tren and just use a little dose for fat loss

Yeah, I mean, I don't think it's super-relevant because regardless of what it does to IGF1, tren is still a great growth compound

 

[dinfar1337]

Yeah, I mean, I don't think it's super-relevant because regardless of what it does to IGF1, tren is still a great growth compound

so well that goes to say local igf-1 in muscle tissue where we want is maxed out now so taking more hgh than needed is just useless besides recovery and fat loss

so yes fuck systemic igf-1.

tren is the power of gods

 

[Deadpool99]

it means ur body needs a break or at the least lower the dose

Turns out it was wasn’t tren. Prime suspect was KSM-66, removing it made a difference

 

[Anonymous35]

It would be IGF1, not GH, but I don't know where on the spectrum of bro-science that falls on

Some studies show tren increases IGF1 or signaling at the IGF1 receptor

Its does decrease igf1 because of the used of dostinex

 

[Raiders789]

Hey guys, feeling really good rn and wanted to share my(limited) experience with tren -

Before this cycle, I've only ever tried microdosing tren ace with trt - I did a short trial of 175 test and 70 tren a(10/day). Instantly got insomnia and anxiety like crazy and that experiment only lasted a week.

A few weeks ago I started a mini cycle of 500 test, 150npp, 200 mast, and 30 var(prewokout 6x/week). After the first week, I added in 10mg tren a/day and didn't notice any sides. Then I dropped the npp and worked my way up to 40mg tren ace/day, and I feel amazing. It almost feels like my CNS got an upgrade; all my lifts are going up despite being in a big defect and I just feel great in the gym. No problem going to failure and getting ridiculous pumps when lifting fasted. And I just feel so much more focused now too - absolutely dialed in the gym, and way more productive outside of it. The only downside so far is that like once a day for like 20 minutes I will just get ridiculously angry for no reason, and if I'm in public when it happens I'll get some intense anxiety. But for the rest of the day I find myself in such a positive and happy mood I'll gladly take the tradeoff.

Also I have hypovoluemic pots, and this is the first blast I've done in a bit. While just on trt I really had to push my sodium and fluid intake just to keep my bp ~90/55, and really struggled to get pumps in the gym due to blood pressure getting too low. Still had that issue when I started the cycle, adding in the test/gh/npp/mast/var all at once put on a lot of water weight but barely touched my bp. Now on the 40 tren ace/day my bp sits at 105/70, and the pots is basically a non-issue. No postural change lightheadness, and have been getting monster pumps.

Literally crazy how much tren has changed my life in such a short time. Idk maybe I'm speaking too soon but just wanted to share my experience so far, I feel like I never hear stories about tren positively affecting people(besides the gains).

 

[monster8912]

Hey guys, feeling really good rn and wanted to share my(limited) experience with tren -

Before this cycle, I've only ever tried microdosing tren ace with trt - I did a short trial of 175 test and 70 tren a(10/day). Instantly got insomnia and anxiety like crazy and that experiment only lasted a week.

A few weeks ago I started a mini cycle of 500 test, 150npp, 200 mast, and 30 var(prewokout 6x/week). After the first week, I added in 10mg tren a/day and didn't notice any sides. Then I dropped the npp and worked my way up to 40mg tren ace/day, and I feel amazing. It almost feels like my CNS got an upgrade; all my lifts are going up despite being in a big defect and I just feel great in the gym. No problem going to failure and getting ridiculous pumps when lifting fasted. And I just feel so much more focused now too - absolutely dialed in the gym, and way more productive outside of it. The only downside so far is that like once a day for like 20 minutes I will just get ridiculously angry for no reason, and if I'm in public when it happens I'll get some intense anxiety. But for the rest of the day I find myself in such a positive and happy mood I'll gladly take the tradeoff.

Also I have hypovoluemic pots, and this is the first blast I've done in a bit. While just on trt I really had to push my sodium and fluid intake just to keep my bp ~90/55, and really struggled to get pumps in the gym due to blood pressure getting too low. Still had that issue when I started the cycle, adding in the test/gh/npp/mast/var all at once put on a lot of water weight but barely touched my bp. Now on the 40 tren ace/day my bp sits at 105/70, and the pots is basically a non-issue. No postural change lightheadness, and have been getting monster pumps.

Literally crazy how much tren has changed my life in such a short time. Idk maybe I'm speaking too soon but just wanted to share my experience so far, I feel like I never hear stories about tren positively affecting people(besides the gains).

It is awesome to hear tren having a positive impact for you. Im on week 13 of a blast started with 50mg ed, then 75 and finishing with 100mg ed. Has been an incredible blast, complete recomp and huge strength gains. Im much more focused on whatever task im doing and have been an overall more positive happy person. Trens not for everyone, but it is incredible for those who aren't hit by the side effects or mental changes.

 

[ve79]

It is awesome to hear tren having a positive impact for you. Im on week 13 of a blast started with 50mg ed, then 75 and finishing with 100mg ed. Has been an incredible blast, complete recomp and huge strength gains. Im much more focused on whatever task im doing and have been an overall more positive happy person. Trens not for everyone, but it is incredible for those who aren't hit by the side effects or mental changes.

I only took 75mg a week and had amazing recomp

 

[AbsoluteKnight]

Any of yall know where I could get some tren hex? Preferably at 200mg/ml