YK-11, the SARM Exception?

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YK-11, the SARM Exception?

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Ever wondered if YK-11 is really a SARM or something else entirely? Get the lowdown on how SARMs compars to Anavar in muscle-building potential, safety concerns, dosing, and why it demands serious caution despite its promise.

This article dives deep into YK-11’s unique steroidal structure, its dual action as an androgen receptor activator and myostatin inhibitor, and why it stands apart from conventional SARMs like LGD-4033 and MK-773.


Author


Cormac Mannion (Type-IIx)

Date


Wednesday, December 17 2025

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Table of Contents


  1. YK-11 the SARM Exception?
    1. YK-11: The Steroidal Outlier in the SARM World
    2. Author
    3. Date
    4. Table of Contents
    5. Key Takeaways
  2. YK-11, The SARM Exception
    1. YK-11’s Molecular Structure and Chemical Classification
      1. Myostatin Inhibition Through Follistatin Upregulation
    2. Comparative Analysis: YK-11 versus Conventional Selective Androgen Receptor Modulators
      1. Structural and Mechanistic Comparison with LGD-4033 and MK-773
    3. Clinical Research Findings: Efficacy and Safety Profile
      1. SARMs vs. ANAVAR: The Results Are In, and It’s Not Really Close
    4. Summary
    5. About the Author
    6. Sign Up for Type-IIx’s Newsletter
    7. References
Key Takeaways

Key Takeaways

• YK-11 works through both androgen receptor activation and myostatin inhibition, unlike traditional SARMs that rely solely on selective receptor binding
• The compound’s 3-keto-4-ene steroidal core (like testosterone’s) fundamentally differs from non-steroidal SARMs like LGD-4033
• The research reveals YK-11 as a hybrid compound that blurs the lines between SARMs, myostatin inhibitors, and anabolic-androgenic steroids, offering exceptional muscle-building potential while demanding heightened caution due to its unknown safety profile and regulatory uncertainties.
• In human clinical trials, Anavar blows the SARMs away in terms of efficacy and tolerability. It’s the natural choice unless legal risks or pinning scare yah! It’s an appropriate drug for women, but so is Anavar!

YK-11 is interesting. It’s not your typical SARM. In fact, we might fairly ask: is it even one?

While classified alongside Ligandrol (LGD-4033) and Ostarine (MK-2866), YK-11 deserves a second look – maybe not for people who’ve already or are otherwise willing to use real gear. But certainly for women, those for whom legal risks are greater like those in police work whose concerns are that the “slippery slope” from TRT+ might lead them afoul of the law by eventually deciding to use illegal drugs. And even for many young men, too – who aren’t willing to pin, don’t want to risk significant hepatotoxicity (liver stress), and who (rightly) care about their fertility. Since while not true that SARMs are totally nonsuppressive… it is true that they are only very mildly risky for fertility, and generally only minimally (albeit certainly) suppress LH, sometimes without affecting FSH significantly – and so therefore – spermatogenesis.

So, this begs the question: how do SARMs stack up against a real anabolic-androgenic steroid (AAS) like Anavar?

Well, let’s talk about that! I’ll wrap up this article with a comparison between clinical trial results from the selective androgen receptor modulator (SARM), MK-0773 (MK 773) versus oxandrolone (Anavar).

While I am confident that you’ll agree that YK-11 is the most interesting in the class; it’s also the least researched, with no human trials.

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If you want to use yk11...use injectable because they showed that it had shirt half life in animal trial. And besides that it's crazy when injected. Just make sure you get real yk. It's been years since my inject sarm cycles and with the raw market right now idk what's going around cuz sarm raws are way more and rarer than roids cuz less demand. I've had a few amazing cycles on inject yk11. I probably have found the most research files about yk11. I should post them but it's my first time back in a while. I might have to look in my old fone for the links unless I can find em real quick. People do a lot of sarm N roid hybrid cycles and they waste their time cuz the sarm is kicking the roid off the androgen receptors cuz they say more selective for it. Thats why tren was more like a sarm than a roid cuz it's way more selective for the AR than other roids but has a lot of side effects unlike sarns. And so the big mystery on YK 11 everybody thinks it's a dht, it behaves like a dht in the body but is actually a 19 nor. If anybody would actually like to know more I can explain but most people hate on sarms but there's a few sarms worth looking at. I've tried every roid and my best cycles were probably my inject yk cycles and good inject lgd 4 cycles also.
 
If you want to use yk11...use injectable because they showed that it had shirt half life in animal trial. And besides that it's crazy when injected. Just make sure you get real yk. It's been years since my inject sarm cycles and with the raw market right now idk what's going around cuz sarm raws are way more and rarer than roids cuz less demand. I've had a few amazing cycles on inject yk11. I probably have found the most research files about yk11. I should post them but it's my first time back in a while. I might have to look in my old fone for the links unless I can find em real quick. People do a lot of sarm N roid hybrid cycles and they waste their time cuz the sarm is kicking the roid off the androgen receptors cuz they say more selective for it. Thats why tren was more like a sarm than a roid cuz it's way more selective for the AR than other roids but has a lot of side effects unlike sarns. And so the big mystery on YK 11 everybody thinks it's a dht, it behaves like a dht in the body but is actually a 19 nor. If anybody would actually like to know more I can explain but most people hate on sarms but there's a few sarms worth looking at. I've tried every roid and my best cycles were probably my inject yk cycles and good inject lgd 4 cycles also.
Would love to learn more about your experiences w YK!

What dose were you running ?

How long did you run it for?

What else were you taking / stacking ?

Any sides?

Did it affect your labs at all? Kidney, liver, lipids etc?

I really enjoyed it when I ran it

Would like to run it again
 
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