tren advice

[IndividualMan]

That's it man, and all that I'm trying to do here on Meso, is get gents to look things up that have credible research points to establish conscious thought. I like helping so that dudes can move forward intelligently.

I think the greatest downfall to PEDS and enhancement is the continuous repeat of dead rhetoric.

This dude in the photo image was my first baby sitter. My Dad would have to split to work and such leaving my brother and I alone at a really young age. Chris lived down the street at the time and was a scrawny dude, but cool guy. Now look at him and vegan.

We can break the rules over and over or learn from them.

View attachment 378448

crazy. Vegan and a pro, without a fucked midsection. kudos to him.

 

[shredded.lyfe]

i did a fuckload of "research" on stacking glp-1s about a month ago bc i was interested in getting the glucagon effect from reta on top of my tirz.

there are a LOT of people who do stack them, and it seems to be relatively safe if the doses arent stupid. but a couple posts that seemed to be well-informed mentioned that they will essentially compete and then you get the effect of the stronger one so the weaker on loses. and apparently tirz is better at targeting glp and gip, so all but the glucagon from the reta is "wasted" or some shit, i dont remember fully but thats basically the gist.

im going to try and find the exact posts brb

Reta has a stronger binding affinity for GIP and GLP1, atleast 6x stronger from memory.

Stacking tirz ontop is a waste that bioscience genius' love to do because they think they're so fkn smart

Did you know there's people out there that still believe taking testosterone is in addition to your natural levels? Wild hey

 

[hellerhiwater]

Reta has a stronger binding affinity for GIP and GLP1, atleast 6x stronger from memory.

Stacking tirz ontop is a waste that bioscience genius' love to do because they think they're so fkn smart

Did you know there's people out there that still believe taking testosterone is in addition to your natural levels? Wild hey

apparently its only stronger on the gip, but tirz stays longer.

from a member named @Ghoul who seemed to know what they were talking about all the time:

"“Its GLP-1 receptor activity is roughly 2× stronger than Retatrutide’s, while its GIP receptor activity is about 5 to 9 times weaker (but once attached has a longer “residence time” than Reta GIP).“

Even though Reta has stronger potency at the GIP receptor, its faster off-rate and shorter residence time mean it binds, signals, and releases quickly.

When Tirz is sitting on those receptors Reta can’t simply bump it off, it just has to wait for a receptor to free up. Since Tirz dissociates slowly, very few openings appear and Tirz still monopolizes GIP sites,

Tirz also has a stronger albumin binding mechanism, and a steady, continuous rate of release. Reta detaches and reattaches much more dynamically (this gives Reta some kind of pulsatile advantage over Tirz I don’t quite understand yet), but it also means Tirz’s steadier plasma concentration is another reason it dominates shared receptors when both are in your system at the same time, throwing off Reta’s balance.""

 

[lucasj782]

Tren ace is hell of a lot more addictive than tren enanthate. It hits harder for a lower dose.


What's with the micro dosing stacks these days? I can't advise blasting gear on a harm reduction forum but it seems like the shitness industry is doing this weird circle jerk advising weird stacks of drugs under the illusion it's safer.

Do TRT or do a cycle. Why muddy the lines?

It just seems so weird people will do low test with primo or micro dose tren but won't run a fat dose of testosterone.

I was guilty of this in the beginning doing these retarded cycles of 150mg test and 200mg deca and 400mg masteron and then 200mg primo. On these dumb arse cycles my bloods were worse than the exact same mg or more of mainly testosterone.

Anyway I'll see myself out.

150 test every other day. been on gear for 6 months 70 tren 525 test 50 var 6 iu growth and multiple glps is hardly trt

 

[lucasj782]

Look in the mirror and point to the part of your physique that absolutely can not get any better unless you start tren....

I looked at your pictures. You barely even look like you workout natty

Just run test and eat dude

for going from 150 to 220 lbs titrating up test only to a measly 400-500mg in less than 6 months think i did a pretty damn good fucking job but yea ill just add more test than i can handle without sides and stuff my face and get obese for no reason thanks for the advice

 

[bananafeet]

150 test every other day. been on gear for 6 months 70 tren 525 test 50 var 6 iu growth and multiple glps is hardly trt

Sorry I misread your original post. I've got a bee in my bonnet about this particular issue and probably just read what I wanted to read.

But still. Why run growth when you could just up the testosterone dose and drop everything else. I don't see the benifit of those other drugs.

There is a study on military men on 200mg of testosterone per week vs naturals. They were both underfed and over trained. The 200mg test group gained muscle and lost fat. The natural group withered away.

So even tho test has no progestogenic effects due to the 19th carbon it does help hold on to muscle. All the other drugs might be overkill.

 

[IndividualMan]

Sorry I misread your original post. I've got a bee in my bonnet about this particular issue and probably just read what I wanted to read.

But still. Why run growth when you could just up the testosterone dose and drop everything else. I don't see the benifit of those other drugs.

There is a study on military men on 200mg of testosterone per week vs naturals. They were both underfed and over trained. The 200mg test group gained muscle and lost fat. The natural group withered away.

So even tho test has no progestogenic effects due to the 19th carbon it does help hold on to muscle. All the other drugs might be overkill.

GH is never a waste. extra lipolysis is big, the tren might be a bit much, but its nice to try new stuff (especially at low/reasonable doses)

 

[bananafeet]

GH is never a waste. extra lipolysis is big, the tren might be a bit much, but its nice to try new stuff (especially at low/reasonable doses)

HGH makes me prediabetic every time I use it. I'm not a big fan to be honest.

Also does it really cause myofibrilar hyperplasia when in a cut?

From my experience (limited). The big levers are:
1. Heavy weights
2. Food
3. Sleep
4. AR signalling (steroids)

After that maybe insulin, igf1 and slowing catabolism (tren, hyperinsulinemia).

 

[IndividualMan]

HGH makes me prediabetic every time I use it. I'm not a big fan to be honest.

Also does it really cause myofibrilar hyperplasia when in a cut?

From my experience (limited). The big levers are:
1. Heavy weights
2. Food
3. Sleep
4. AR signalling (steroids)

After that maybe insulin, igf1 and slowing catabolism (tren, hyperinsulinemia).

overall trvth, but i would check my insulin sensitivity if GH makes you prediabetic while cutting. for me that (insulin resistance in my case, am already T1D) only happens above 15% bf or when I eat lots of fat/ vegetable protein multiple days in a row.
maybe add mots-c or something along those lines, might be worth a try.

the hyperplasia does not happen at the dosages described here btw, but there should not be a major difference between cut and bulk.

all the big levers you listed are indeed the main things to pay attention to.

 

[lucasj782]

GH is never a waste. extra lipolysis is big, the tren might be a bit much, but its nice to try new stuff (especially at low/reasonable doses)

yea i only plan on at most doubling tren to 140 if 70 is underwhelming just so i can cut a bit more aggressively. bloodwork even on var test and gh is perfect besides low hdl. after im back to single digit bodyfat ill run a growth phase on just test and gh, maybe a bit of eq and nothing else besides low dose glps and ancillaries. just figure why not have some fun and get a bit saucy while i diet to speed the process up and get back to growing

 

[lucasj782]

overall trvth, but i would check my insulin sensitivity if GH makes you prediabetic while cutting. for me that (insulin resistance in my case, am already T1D) only happens above 15% bf or when I eat lots of fat/ vegetable protein multiple days in a row.
maybe add mots-c or something along those lines, might be worth a try.

the hyperplasia does not happen at the dosages described here btw, but there should not be a major difference between cut and bulk.

all the big levers you listed are indeed the main things to pay attention to.

reta definitely helps on 6 iu growth even a bit above 15% eating 6-700 grams of carbs a day my a1c was 4.6 and 74 fasting glucose. fasting insulin a bit high at 5 though

 

[bananafeet]

Come on bro.... HGH is mainly a diabetogenic drug with the side effect of influencing the igf1 level.

Just like testosterone is mainly androgenic before it's anabolic (especially in women).

Similarly how tren is anti catabolic before it's anabolic .

HGH stops insulin from working properly. I'd rather take Metformin and testosterone.

 

[Elektrobot]

for going from 150 to 220 lbs titrating up test only to a measly 400-500mg in less than 6 months think i did a pretty damn good fucking job but yea ill just add more test than i can handle without sides and stuff my face and get obese for no reason thanks for the advice

Dude I am seriously not trying to rag on you, but you gotta be honest with yourself

Your physique is at stage 1. You don't look like you have a solid training program or food plan. You are unbalanced and soggy. You don't even have abs or chest yet, but think tren is the only thing holding you back?

You have low lying fruit to capitalize on which will make even better improvements than tren will.

Get the first steps right before worrying about starting step 100

 

[lucasj782]

Dude I am seriously not trying to rag on you, but you gotta be honest with yourself

Your physique is at stage 1. You don't look like you have a solid training program or food plan. You are unbalanced and soggy. You don't even have abs or chest yet, but think tren is the only thing holding you back?

You have low lying fruit to capitalize on which will make even better improvements than tren will.

Get the first steps right before worrying about starting step 100

my point exactly. according to you im soggy yet adding more test and more food and becoming fatter is somehow the answer. as stated in another comment ive gotten too fat and im low dosing tren to preserve some size while i get lean and to have a lil fun then ill be pushing test only to build tissue.

 

[bananafeet]

my point exactly. according to you im soggy yet adding more test and more food and becoming fatter is somehow the answer. as stated in another comment ive gotten too fat and im low dosing tren to preserve some size while i get lean and to have a lil fun then ill be pushing test only to build tissue.

Steroid myonucler gains are permanent. Glycogen and electrolyte retention is not


You're not gonna lose muscle going off just fluid