Reta Microdosing (<1.5mg) to improve lipids?

[Banana Joe]

I had already asked here, but it sadly didn't get any replies.

How many of you guys are taking microdoses of Reta (<1.5mg?) mainly to improve HDL/LDL?
I have seen quite a few people on YT making similar claims, but Big Paul is the first one that provided actual numbers.

Other benefits should be:
- improved insulin sensitivity (might be even a given)
- reduced visceral and liver fat via glucagon receptor signaling


I always had bad HDL/LDL (hereditary) and have started taking 0.2mg e2d of Reta just recently. So far I feel no reduction in appetite, which is critical for me, as I have become a terrible eater over the years. If I feel no ill effects, I might up the dose to 0.3mg e2d.
Haven't gotten a new blood panel as my diet is a bit terrible atm, and I need to fix that first to get any meaningful data.

 

[phenominal34]

Nick Walker just claimed in this video (got no timestamp, sorry) he didn't go north of 2mg of Reta, and praised its health benefits at that dose (and below).

Might be that is lying like many pros, but I have never seen Nick speaking about dosages, or that made claims he is on whatever unbelievably low amount that some guys claim to be.
Therefore I don't see not much evidence to doubt his claims when speaking about Reta of all drugs.

Studies showed the increased health benefits don’t occur until higher dosages 8mgs so tough to believe

 

[Banana Joe]

Studies showed the increased health benefits don’t occur until higher dosages 8mgs so tough to believe

Had written a long rebuttal to this, but at the end I can just ask:

Have you even read this thread?

I am asking because we got multiple liars like Nick Walker, that are just members here, that posted about their results in a similar manner.

 

[Liter O' Test]

i just started 1mg tirz. hoping to get all the little perks like less inflammation, and i hear tirz is more geared towards this than reta, and glucagon is kind of a mystery and somehow involved in the stress response.

i went off my diet for one day and i feel beat up

 

[phenominal34]

Had written a long rebuttal to this, but at the end I can just ask:

Have you even read this thread?

I am asking because we got multiple liars like Nick Walker, that are just members here, that posted about their results in a similar manner.

I’ve read the thread yes. You said you didn’t doubt his claims, I 100% doubt his claims.

 

[Banana Joe]

I’ve read the thread yes. You said you didn’t doubt his claims, I 100% doubt his claims.

Then please provide citation and name of the studies for your 8mg or bust claim, that evidently falsifies the testimony of such vile liars such as @madcap71, @juicybanana69 and @AIRBORNE DADDY (which didn't provide numbers but mentioned being on just 6mg), and that video by Big Paul where he shows a graph of his LDL after changing nothing, but adding the 1.5mg of Reta. Did Big Paul make that graph up and/or lie about his Reta dosages for this video?

While you provide those citations, please also put the results, of those studies, into the context of a male, who is low bodyfat, hyper muscular by any medical standard, has high insulin sensitivity, that can eat close to or north of 1000g of carbs, with a fasted blood glucose <90, does heavy resistance training for hours a week, plus hours of cardio, eats a healthy and protein rich, low fat diet, and that takes steroids and other BB related drugs.
Can you find just one fitting that description in ALL studies of GLP1 drugs?

Regarding Nick Walker, this is what I actually wrote, in the context of mentioning that many pros lie about their dosages:
"I don't see not much evidence to doubt his claims"
Now, you can disagree with my reasoning for what I wrote, but this is not the same as writing that "I don't doubt his claims". Not being able to tell those two things apart from each other makes me question your qualification to do as asked above.

 

[Banana Joe]

i just started 1mg tirz.

Not gonna work bro. Studies say so.

On a more serious note, can you please further elaborate why you chose Tirz if you are more looking for the secondary effects of those GLP1 drugs?
My, perhaps poorly executed, search results were that appetite suppression and gastric side effects can or will be higher on 1st and 2nd gen GLP1 drugs, but that Reta is otherwise equal or superior in (all?) other regards.

Since I have no interest in appetite suppression I therefore went with Reta.

 

[Liter O' Test]

Not gonna work bro. Studies say so.

On a more serious note, can you please further elaborate why you chose Tirz if you are more looking for the secondary effects of those GLP1 drugs?
My, perhaps poorly executed, search results were that appetite suppression and gastric side effects can or will be higher on 1st and 2nd gen GLP1 drugs, but that Reta is otherwise equal or superior in (all?) other regards.

Since I have no interest in appetite suppression I therefore went with Reta.

im not sold on glucagon being a good thing and tirz has better effect on BG. glp-1 seems to be more anti inflammatory and reta is split 3 ways so i think less effect on the glp-1 pathway
the fact reta is pushed by all these guys sponsored or selling it like its a totally different class of drugs compared to tirz is big red flag for me. try to find info on bodybuilders running tirz, no they just hop to reta because someone told them to, but i generally dont go with the mainstream anyway because of my ego.

 

[Ghoul]

im not sold on glucagon being a good thing and tirz has better effect on BG. glp-1 seems to be more anti inflammatory and reta is split 3 ways so i think less effect on the glp-1 pathway
the fact reta is pushed by all these guys sponsored or selling it like its a totally different class of drugs compared to tirz is big red flag for me. try to find info on bodybuilders running tirz, no they just hop to reta because someone told them to, but i generally dont go with the mainstream anyway because of my ego.

also, if reta doesnt affect peoples appetite as much AND doesnt control BG as well as tirz, then what is it actually doing?

Tirz is better for glucose control.

Interestingly Sema is able to cross the blood brain barrier easily where Tirz and Reta can't. There are very likely benefits unique to Sema, since the brain is rich with GLP receptors.

For BB use the weak appetite suppression is a feature not a bug, getting benefits and still being able to eat, but like you said, if it's not as good for diabetics, or for straight weight loss via potent appetite suppression, what is the commercial market for Reta when Tirz is already a blockbuster for Eli Lily.

The new 20 and 25mg doses close the gap with Reta on weight loss, and extend the lead in glucose control.

In the meantime we've got new GLP/Muscle sparing combos around the corner.

 

[newguy2]

Tirz is better for glucose control.

Interestingly Sema is able to cross the blood brain barrier easily where Tirz and Reta can't. There are very likely benefits unique to Sema, since the brain is rich with GLP receptors.

For BB use the weak appetite suppression is a feature not a bug, getting benefits and still being able to eat, but like you said, if it's not as good for diabetics, or for straight weight loss via potent appetite suppression, what is the commercial market for Reta when Tirz is already a blockbuster for Eli Lily.

The new 20 and 25mg doses close the gap with Reta on weight loss, and extend the lead in glucose control.

In the meantime we've got new GLP/Muscle sparing combos around the corner.

Does Reta help appetite control at all. I am thinking of using it. Been on Tirz, even in a bulk if I manage the dose properly I can eat but it helps with discipline and not over doing it. Does Reta give this benefit? Or should I just stick with Tirz?

 

[Ghoul]

Does Reta help appetite control at all. I am thinking of using it. Been on Tirz, even in a bulk if I manage the dose properly I can eat but it helps with discipline and not over doing it. Does Reta give this benefit? Or should I just stick with Tirz?

IMO, if it ain't broke, don't fix it.

You have a dose that works for you. You know how to deal with it, and it's significantly cheaper.

Reta for BB seems best suited for those who can't use any effective dose of Tirz without causing too much appetite suppression, or they suffer from fatigue on Tirz.

 

[verylargeshoes]

Does Reta help appetite control at all. I am thinking of using it. Been on Tirz, even in a bulk if I manage the dose properly I can eat but it helps with discipline and not over doing it. Does Reta give this benefit? Or should I just stick with Tirz?

Sure, it does to some degree, and for me it was in a qualitatively different way. My experience with Reta is that it doesn't reduce my appetite commensurately with its effects on my digestive processes. If I'm just eating until satiated, I can easily eat more than my body will comfortably handle.

With Tirz, that never really happened. My appetite was the limiting factor. I was not naturally likely to "out eat" my rate of gastric emptying.

TIrz would make the mere thought of eating unpleasant at times. Reta never really did that, though for whatever reason I did tend to eat less. YMMV.

When trying to diet, I'd personally prefer Tirz if not for the fatigue that came with it. Reta's great for less calorically restrictive periods.

 

[newguy2]

IMO, if it ain't broke, don't fix it.

You have a dose that works for you. You know how to deal with it, and it's significantly cheaper.

Reta for BB seems best suited for those who can't use any effective dose of Tirz without causing too much appetite suppression, or they suffer from fatigue on Tirz.

The fatigue thing has me curious. My wife has been on it for like three months and never noticed it. But the last couple weeks she has been complaining about fatigue. I have mentioned the tirz but seems odd it would be this delayed.

I'm curious in the tirz is having even a minimal effect of fatigue on me (or her) this seems undesirable.

I agree on the price, tirz just keeps going down. Reta holds pretty good lately. But the minimum vial size keeps going up. I want nothing to do with a vial that will take me 6 weeks+ to go through.

Sure, it does to some degree, and for me it was in a qualitatively different way. My experience with Reta is that it doesn't reduce my appetite commensurately with its effects on my digestive processes. If I'm just eating until satiated, I can easily eat more than my body will comfortably handle.

With Tirz, that never really happened. My appetite was the limiting factor. I was not naturally likely to "out eat" my rate of gastric emptying.

TIrz would make the mere thought of eating unpleasant at times. Reta never really did that, though for whatever reason I did tend to eat less. YMMV.

When trying to diet, I'd personally prefer Tirz if not for the fatigue that came with it. Reta's great for less calorically restrictive periods.

Yeah I went from 2.5 to 5 like the standard protocol after a month and that week was rough. Looking at my morning shake made me sick, struggled all day to get the food down and afterward always felt super bloated. If I did say screw it and over eat I would very much regret it for a few hours.

I'm in a bulk right now, I usually struggle more in a bulk that a cut as the reigns are off a bit and I feel like it's time to eat. So just wanting something to keep that in check. Looking at the overall benefits of reta. But it may just be fomo that everyone else is on the newest glp1 and I should be too.

 

[RockyP]

All the GLP-1 drugs cause weight loss, which will improve lipids. Like Ghoul said, add in some Pita and Zetia to drop the hammer on dyslipidemia.

 

[phenominal34]

Then please provide citation and name of the studies for your 8mg or bust claim, that evidently falsifies the testimony of such vile liars such as @madcap71, @juicybanana69 and @AIRBORNE DADDY (which didn't provide numbers but mentioned being on just 6mg), and that video by Big Paul where he shows a graph of his LDL after changing nothing, but adding the 1.5mg of Reta. Did Big Paul make that graph up and/or lie about his Reta dosages for this video?

While you provide those citations, please also put the results, of those studies, into the context of a male, who is low bodyfat, hyper muscular by any medical standard, has high insulin sensitivity, that can eat close to or north of 1000g of carbs, with a fasted blood glucose <90, does heavy resistance training for hours a week, plus hours of cardio, eats a healthy and protein rich, low fat diet, and that takes steroids and other BB related drugs.
Can you find just one fitting that description in ALL studies of GLP1 drugs?

Regarding Nick Walker, this is what I actually wrote, in the context of mentioning that many pros lie about their dosages:
"I don't see not much evidence to doubt his claims"
Now, you can disagree with my reasoning for what I wrote, but this is not the same as writing that "I don't doubt his claims". Not being able to tell those two things apart from each other makes me question your qualification to do as asked above.

"I don't see not much evidence to doubt his claims"

You can type all your study bullshit but when you type a sentence like that above …

I chuckle and say poor guy…. Maybe he didn’t do well in English.

I will most definitely not be searching for your hand picked studies lol I know what I read from a bunch of guys and gals who say omg I can’t hardly take 1mg of Reta a week I’m vomitting and had to ho to the ER!! They either don’t know how to reconstitute a vial with correct BAC or what units on an insulin needle mean. Or they are complete idiots. My guess is 3.

It’s like saying I took a sip of beer and I blacked out and had to get my stomach pumped.

 

[Banana Joe]

You can type all your study bullshit but when you type a sentence like that above …

I chuckle and say poor guy…. Maybe he didn’t do well in English.

I will most definitely not be searching for your hand picked studies lol I know what I read from a bunch of guys and gals who say omg I can’t hardly take 1mg of Reta a week I’m vomitting and had to ho to the ER!! They either don’t know how to reconstitute a vial with correct BAC or what units on an insulin needle mean. Or they are complete idiots. My guess is 3.

It’s like saying I took a sip of beer and I blacked out and had to get my stomach pumped.

You are creating another straw man argument. I am not gonna argue with you anymore, as you have brought forward nothing of any substance after multiple posts.
English might not be my first language, but it is surely good enough to spot people of low intelligence, and you are most certainly one. For the Lulz I took 30sec and went trough the first three pages of your post history, 80-90% are one line posts. This post was admittedly longer, but shows clearly you have no sense for grammar, nor how to compose a proper sentence. That is not the handwriting of someone reading studies to cite their content.
In the time you typed this up, you could have also provided a single citation, that is substantiating your initial claim. As someone, who reads and understands studies, that should have taken you 30-120sec.

Now feel free to prove me wrong, with your superior knowledge and excellent command of the English language.

EDIT: Two smileys for me, how cute!

 

[phenominal34]

You are creating another straw man argument. I am not gonna argue with you anymore, as you have brought forward nothing of any substance after multiple posts.
English might not be my first language, but it is surely good enough to spot people of low intelligence, and you are most certainly one. For the Lulz I took 30sec and went trough the first three pages of your post history, 80-90% are one line posts. This post was admittedly longer, but shows clearly you have no sense for grammar, nor how to compose a proper sentence. That is not the handwriting of someone reading studies to cite their content.
In the time you typed this up, you could provided a single citation substantiating your initial claim. As someone, who reads and understands studies, that should have taken you 30-120sec.

Now feel free to prove me wrong, with your superior knowledge and excellent command of the English language.

Okie Dokie Banana Joe ha. I actually take the drugs and know how they feel … how bout you ?

 

[Liter O' Test]

1mg tirz is working pretty well for me so far, its been 24 hours , i have good receptors I just had some sort of continuing rebound issue after my cut this spring that stopped me from getting the full signals and I developed way too much emotions around food, when my whole life food had like 0 effect on me and I never sought out anything delicious. I suspect part of this was due to a nutrient defiency during the cut that slowed my metabolism much lower than the calories I was consuming putting an extreme amount of stress on me despite having relatively sufficient calories.

anyway, my calories crept up slowly to 3500-3800 this past week and today, the day after my first tirz dose, I am at 2500 calories and im getting full signals again and I am actually satisfied after eating. Also i used about half as many nicotine pouches as usual.

One of the main things that pushed me to try glps again was having to rely on a ton of nicotine pouches to suppress appetite

 

[Banana Joe]

I actually take the drugs and know how they feel … how bout you ?

Not at all relevant to any part of this discussion, and already answered in the very FIRST post of this thread - that you claimed to have read.
You are making this very easy for me, actually to a point where I feel you get off on degrading yourself.

 

[Banana Joe]

All the GLP-1 drugs cause weight loss, which will improve lipids. Like Ghoul said, add in some Pita and Zetia to drop the hammer on dyslipidemia.

This thread was never opened in the context of Reta improving lipids by weight loss, but by other mechanisms, that are apparently still at play if one plateaus in weight or even gain it.
We have now seen that multiple claims that Reta does improve lipids, even when there is no weight loss occurring.

At this point there must be hundreds of threads centering around weight loss and appetite suppression of GLP1 drugs. This one was clearly noted to be about something else, as the title should already indicate.

 

[Banana Joe]

1mg tirz is working pretty well for me so far, its been 24 hours , i have good receptors I just had some sort of continuing rebound issue after my cut this spring that stopped me from getting the full signals and I developed way too much emotions around food, when my whole life food had like 0 effect on me and I never sought out anything delicious. I suspect part of this was due to a nutrient defiency during the cut that slowed my metabolism much lower than the calories I was consuming putting an extreme amount of stress on me despite having relatively sufficient calories.

anyway, my calories crept up slowly to 3500-3800 this past week and today, the day after my first tirz dose, I am at 2500 calories and im getting full signals again and I am actually satisfied after eating. Also i used about half as many nicotine pouches as usual.

One of the main things that pushed me to try glps again was having to rely on a ton of nicotine pouches to suppress appetite

Your now deleted part of your post post made me believe that you are taking Tirz for other reasons than appetite suppression, notably reducing inflamation, blood glucose levels and insulin sensitivity.