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Anabolic Steroids

HGH and deep sleep

Prince Charming

Prince Charming

New Member
Hey guys I’ve been on hgh for about a month now, started at 2iu at night and worked my way up to 4 starting yesterday. I’ve yet to experience any sides outside of my sleep being all out of wack. I take it at 12am, about 1hr an 30 mins before bed(1:30 am). My final meal is always at 8:30pm to make sure blood glucose has come down before injecting.

Something I’ve noticed from the start is how it affects my sleep. My sleep went down from averaging 7 hrs to me hardly being capable of sleeping 5 hrs. I wear an Apple Watch every night and something I’ve noticed is that I pretty much get no deep sleep, all is in core and rem. Another thing is that my rhr is like 10 beats hire throughout the night and I’m thinking maybe the watch isn’t able to distinguish from deep and core sleep anymore. I’ve been taking 2mg fast release and 2.5mg slow release melatonin for the past 3 nights and that has been keeping me asleep for 7-8 hrs but the deep sleep is still mostly non existent.

I’ve been doing a little research and it seems most endogenous hgh would be produced during deep sleep. Since I’m getting more than enough through exogenous administration, maybe my body is telling me there is no need for going into deep sleep? Idk though, maybe one of you guys could educate me some more on this.
 
Prince Charming said:
Hey guys I’ve been on hgh for about a month now, started at 2iu at night and worked my way up to 4 starting yesterday. I’ve yet to experience any sides outside of my sleep being all out of wack. I take it at 12am, about 1hr an 30 mins before bed(1:30 am). My final meal is always at 8:30pm to make sure blood glucose has come down before injecting.

Something I’ve noticed from the start is how it affects my sleep. My sleep went down from averaging 7 hrs to me hardly being capable of sleeping 5 hrs. I wear an Apple Watch every night and something I’ve noticed is that I pretty much get no deep sleep, all is in core and rem. Another thing is that my rhr is like 10 beats hire throughout the night and I’m thinking maybe the watch isn’t able to distinguish from deep and core sleep anymore. I’ve been taking 2mg fast release and 2.5mg slow release melatonin for the past 3 nights and that has been keeping me asleep for 7-8 hrs but the deep sleep is still mostly non existent.

I’ve been doing a little research and it seems most endogenous hgh would be produced during deep sleep. Since I’m getting more than enough through exogenous administration, maybe my body is telling me there is no need for going into deep sleep? Idk though, maybe one of you guys could educate me some more on this.
Click to expand...

The short version is GH boosts several types of brain activity along with stimulating the vagal nerve which increases resting heart rate.

Shift to morning injections and you should return to more normal sleep.
 
Ghoul said:
The short version is GH boosts several types of brain activity along with stimulating the vagal nerve which increases resting heart rate.

Shift to morning injections and you should return to more normal sleep.
Click to expand...
You recommend splitting it 2/2? Or all in morning?

Another question about morning. If subq peak times is 3-4 hrs, how do y’all manage to not eat breakfast for that long? I guess IM would be the move then?
 
Prince Charming said:
You recommend splitting it 2/2? Or all in morning?

Another question about morning. If subq peak times is 3-4 hrs, how do y’all manage to not eat breakfast for that long? I guess IM would be the move then?
Click to expand...

All at once. While increasing GH exposure could boost lipolysis (a GH benefit that stops after Insulin accelerated conversion to IGF and "Growth mode".) the added insulin resistance probably negates any benefit, or worse,

Here's the thing. To recap what you already know: We want to maximize fasting to "capture" the most possible GH boosted lipolysis (liberating free fatty acids from fat cells into the blood stream) so they can be used as energy (hopefully) accelerating fat loss. Once you eat, insulin blunts lipolysis and accelerates conversion of GH to IGF. IGF does all sorts of good things related to tissue growth, other than fat loss. So it's still a benefit.

But it's not On/Off. From what I understand, it's more like a 25/75 split at the most, not all GH benefits or all IGF benefits at any given moment.

So even if you eat, enhanced GH lipolysis continues for the whole window it normally would. (most in the first 6 hours or so of injection I believe). It's just less than it would be in a fasted state.

And the key here is, if you're not doing cardio in that fasted state, it's very unlikely you'd be able to utilize all the ffa as energy before it gets redeposited anyway.

So the bottom line is, by shifting to morning injection, you preserve valuable sleep quality, and since you weren't doing fasted cardio in the post injection window, you weren't burning off all the available ffa's anyway, just a portion. By getting poor sleep. cortisol levels rise, inhibiting fat loss. You'll still see enhanced fat loss with this altered timing and eating soon after, despite the lessened lipolysis effect.
 
Prince Charming said:
Hey guys I’ve been on hgh for about a month now, started at 2iu at night and worked my way up to 4 starting yesterday. I’ve yet to experience any sides outside of my sleep being all out of wack. I take it at 12am, about 1hr an 30 mins before bed(1:30 am). My final meal is always at 8:30pm to make sure blood glucose has come down before injecting.

Something I’ve noticed from the start is how it affects my sleep. My sleep went down from averaging 7 hrs to me hardly being capable of sleeping 5 hrs. I wear an Apple Watch every night and something I’ve noticed is that I pretty much get no deep sleep, all is in core and rem. Another thing is that my rhr is like 10 beats hire throughout the night and I’m thinking maybe the watch isn’t able to distinguish from deep and core sleep anymore. I’ve been taking 2mg fast release and 2.5mg slow release melatonin for the past 3 nights and that has been keeping me asleep for 7-8 hrs but the deep sleep is still mostly non existent.

I’ve been doing a little research and it seems most endogenous hgh would be produced during deep sleep. Since I’m getting more than enough through exogenous administration, maybe my body is telling me there is no need for going into deep sleep? Idk though, maybe one of you guys could educate me some more on this.
Click to expand...
As Ghoul mentioned, you should shift your injections to morning, and you should do it all at once.

Now, what you may find is that even those changes might not help.

For some people, GH use just fucks with sleep quality, no matter what protocol you use.
I am one of those people. Anything more than 2iu, and I’m a zombie. Can’t adjust my way around it.
 
Progesterone and adrenaline… just found this out myself… lower ur dose and see if sleep is better?

Then apply that other part of the dose around workout time… perhaps, maybe..
 
Like the others said, try morning injection all of the dose.

I’d like to say something though, eating last meal at 20:30 and sleeping in 01:30 is nuts. Even with HGH in play, 2 hours is more than enough if you eat plenty of carbs. Without carbs you could eat and pin it right away. Fix your diet because it seems you don’t get any food for 12+ hours.
 
Eddie. said:
Like the others said, try morning injection all of the dose.

I’d like to say something though, eating last meal at 20:30 and sleeping in 01:30 is nuts. Even with HGH in play, 2 hours is more than enough if you eat plenty of carbs. Without carbs you could eat and pin it right away. Fix your diet because it seems you don’t get any food for 12+ hours.
Click to expand...
Thank ya I’m gonna give it a try tomorrow. Already too late in the day now so just gonna skip it today and do first thing. Also yes I’m gonna have to be pushing dinner back. I work second shift so unfortunately can’t sleep any earlier.
 
Rabble said:
As Ghoul mentioned, you should shift your injections to morning, and you should do it all at once.

Now, what you may find is that even those changes might not help.

For some people, GH use just fucks with sleep quality, no matter what protocol you use.
I am one of those people. Anything more than 2iu, and I’m a zombie. Can’t adjust my way around it.
Click to expand...
I’m gonna do some adjustments based on comments here and see how it goes the next few nights. I fear I’m gonna be one of those people too, just have to wait and see.
 
Prince Charming said:
You recommend splitting it 2/2? Or all in morning?

Another question about morning. If subq peak times is 3-4 hrs, how do y’all manage to not eat breakfast for that long? I guess IM would be the move then?
Click to expand...

Meal timing around GH injections is super-minutiae

That is, it's not gonna cause diabetes if you eat the same time as you inject GH, that's not how diabetes works; similar rationale for "optimizing" fat loss
 
Eddie. said:
Like the others said, try morning injection all of the dose.

I’d like to say something though, eating last meal at 20:30 and sleeping in 01:30 is nuts. Even with HGH in play, 2 hours is more than enough if you eat plenty of carbs. Without carbs you could eat and pin it right away. Fix your diet because it seems you don’t get any food for 12+ hours.
Click to expand...
I also take 2 IU of GH before going to sleep, usually about 1.5 hours after my last meal. I also notice a slightly worse sleep quality.


In the morning, I usually wake up at 8 AM and leave at 9 AM for work. During that hour, I should also have breakfast. If I were to move my GH dose to the morning, how could I do it? Would it be a health problem to take GH shortly after having breakfast? (The only source of carbs in my breakfast currently is 100 g of oats.)
 
@ganciodestro I feel the same way. HGH has ruined my sleep. I'd like to inject around 8 a.m. and have breakfast at 8:30 a.m. I don't leave the house without breakfast. Can I do this? Or could it make me diabetic? My fasting blood sugar is 105.
 
Eddie. said:
Like the others said, try morning injection all of the dose.

I’d like to say something though, eating last meal at 20:30 and sleeping in 01:30 is nuts. Even with HGH in play, 2 hours is more than enough if you eat plenty of carbs. Without carbs you could eat and pin it right away. Fix your diet because it seems you don’t get any food for 12+ hours.
Click to expand...
What's wrong with intermittent fasting?
 
Ateam2023 said:
well your well on your way to pre-diabetes with that fbg @105, do you take anything to try and remedy this?
Click to expand...
No. I suspect the cause is the HGH in my case. I still have one bottle; as soon as I'm finished, I'll take a break and see if my blood sugar returns to normal. I occasionally took 1000 mg of berberine before bed, but my fasting blood sugar level was still at 105 in the morning. I don't know why that's happening.
 
serkan said:
No. I suspect the cause is the HGH in my case. I still have one bottle; as soon as I'm finished, I'll take a break and see if my blood sugar returns to normal. I occasionally took 1000 mg of berberine before bed, but my fasting blood sugar level was still at 105 in the morning. I don't know why that's happening.
Click to expand...
Berberine is more impactful taken 15 minutes before carb meals. I would do low dose glp1 if I were you to restore insulin sensitivity.
 
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