That's awesome, I was hoping you'd chime in. You're right, why wait until that blood pressure and high heart rate cause a problem? Good meds are becoming highly available from multiple sources too and easy to get.
You beat me to it, I was going to mention, Primordial prevention has only been possible since modern pharmaceuticals have gotten to the point that in most cases, there’s no downside, no “price” to pay in exchange for a health benefit.
I remember my grandparents meds. Every pill was half cure half poison. Of course you didn’t take that shit until it was absolutely necessary. The more pills someone took, the sicker they looked and closer to death they were.
I think a lot of people are still traumatized by that and have Pharmacophobia. So while a pile of UGL PEDs is no problem, anything pharma (for BP, lipids, etc) causes anxiety and is resisted.
GLPs are a great example (maybe the greatest) of how a pharmaceutical can be all (or almost all) upside.
The first generation in the 90s were reserved for a small group of wealthy patients, as a superior, more convienient alternative to insulin.
But doctors observed an interesting phenomenon. The diabetics using them long term seemed to develop fewer problems and lived longer than their non-diabetic, technically healthier peers.
The same can be said for a bunch of modern drugs. Telmisartan is a good example. Keeps BP in check in a proportional way, so you can use it to keep your “normal” BP in the slightly lower “ideal” range, but when it rises for whatever reason, Telm exerts stronger blood pressure control as needed. The “side effects” are similar to cardarine. Boosts endurance, lowers triglycerides, improves insulin sensitivity, inhibits new fat cell growth, shifts muscle energy use to fatty acids, etc etc.
Just one example of a drug that can be safely taken long in advance of where the current guidelines recommend using a drug, and the most likely result will be better overall health, beyond preventing damage from elevated blood pressure. With careful selection, there are choices like this that can significantly reduce almost all long term health risks.
entions to prevent them. Review Methods: A review was conducted on the basis of an in-depth literature search including longitudinal observational data, systematic reviews and meta-analyses published in 2012 or later, clinical trials, and additional manual searches of recent literature based on...
journals.lww.com
