Steroid Profile Anadrol

[ve79]

Is this still a popular protocol? This is the first time I am reading about it.
I tried to find @Roger Rabbit's post on this, and it seems to kinda make sense, so I am wondering if that could be a way to prevent, or rather decrease, the appetite killing effect of orals, to which I am quite susceptible for.

It's very weird for me with orals I find dbol works better for me than anadrol in the gym but dbol messes with my appetite when drol doesn't

 

[Dj11235813]

That is quite literally a women/children dose.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/16848s021lbl.pdf

BB/PL'ing dose commonly 100mg, up to 200mg for brief periods pre-contest

My next round I definitely plan on upping it depending on how I respond of course. I only grabbed smaller dosing for now to see how my body responds. Shit I’ve seen some posts (not here) of people saying they’ve taken up to 500mg. Not sure if that was BS or not though.

 

[ChemBB]

Shit I’ve seen some posts (not here) of people saying they’ve taken up to 500mg.

The funny thing is that 500mg falls within the FDA guideline dosage range for a 100kg human (100-500mg/day)

 

[Banana Joe]

The funny thing is that 500mg falls within the FDA guideline dosage range for a 100kg human (100-500mg/day)

The only two people that are somewhat on the public record as having taken these 500mg (or higher) are Nasser El Sonbaty and Scott Mendelson (allegedly 20 Anadrol, meaning he took 1000mg ed).

 

[ChemBB]

The only two people that are somewhat on the public record as having taken these 500mg (or higher) are Nasser El Sonbaty and Scott Mendelson (allegedly 20 Anadrol, meaning he took 1000mg ed).

You've clearly not hung out with the meathead types who aren't tech-literature enough to use forums.

Those guys don't even know what/how much they're taking. Not joking.

 

[ChemBB]

As a joke I once drank an entire 30mL vial of Halotestin on camera before a workout when I was 18.

 

[Banana Joe]

You've clearly not hung out with the meathead types who aren't tech-literature enough to use forums.

Those guys don't even know what/how much they're taking. Not joking.

I might have in the past, but I was never the guy to ask much about dosages. I remember one or two that likely fit that description, but I was never one trying to find friends among meatheads.
I still have no idea how anyone, let alone a super heavy weight can eat on 500mg of any oral.

As a joke I once drank an entire 30mL vial of Halotestin on camera before a workout when I was 18.

I guess the only question I have in regards to this is - how was the fucking workout then?

 

[Dj11235813]

My bad, I was meaning just prior to reading your post about it I was in disbelief. lol shit if If my body can handle it, I’ll be picking up those 100’s next cycle!

 

[Banana Joe]

It's very weird for me with orals I find dbol works better for me than anadrol in the gym but dbol messes with my appetite when drol doesn't

I mean it doesn't matter what you take. The same principles of this approach would still apply.
You take a "wet compound" like anadrol, with a "dry" compound like winstrol, halotestin, or even superdrol to get the most of the benefit of the harsh compound, while keeping the side effects at bay.

It sounds good, and I once had come up with a similar scheme for myself, but I am still a bit sceptic if that really works in the real world.

 

[ChemBB]

how was the fucking workout then?

Not the slightest different. I'm really not sold on the "psychoactive steroids" thing, 10 years into using them...

(At least in an acute sense. Definitely seems plausible to have long-term behavioral changes from neuro-steroid + dopamine alterations.)

 

[Eddie.]

The only two people that are somewhat on the public record as having taken these 500mg (or higher) are Nasser El Sonbaty and Scott Mendelson (allegedly 20 Anadrol, meaning he took 1000mg ed).

These are the 2 most known but there’s definitely more people in such high or higher dosages, we may not know them or they just never told it publicly.

What I’m curious about high drol is how is it possible to mess people’s GI at baby dosages of 50mg in bodybuilding world with meticulous diet choices and powerlifters can perform on 8-10K calorie diets with high fats and 200mg+ drol. It’s amazing.

 

[Banana Joe]

Not the slightest different. I'm really not sold on the "psychoactive steroids" thing, 10 years into using them...

Me neither. I could tell that anything ever made me more angry or aggressive in or outside of the gym. If I loose my shit it is entirely dose (or drug) independent....

These are the 2 most known but there’s definitely more people in such high or higher dosages, we may not know them or they just never told it publicly.

I don't doubt that.

What I’m curious about high drol is how is it possible to mess people’s GI at baby dosages of 50mg in bodybuilding world with meticulous diet choices and powerlifters can perform on 8-10K calorie diets with high fats and 200mg+ drol. It’s amazing.

Tell me about it!
It is not like I am even remotely interested in doses of 100mg or above, but I would not ask about such hacks such as this 3d/2d approach, were I able to tolerate any oral stronger than a sugar pill.

 

[RockyP]

As a joke I once drank an entire 30mL vial of Halotestin on camera before a workout when I was 18.

In my 20's used to go out partying and drank my face off while taking tren and 100 mg winstrol daily. Never got bloodwork, never checked blood pressure. Not proud of it. Ashamed of it actually. But that lunacy is what informs my present day approach to harm reduction.

But yeah, I used to roll with lots of dudes who just took whatever they could get their hands on whenever they could.

 

[oldgrey]

Sounds like you had a solid run with the Adrol this time around, esp. with the Mast helping the water retention.

But on the sublingual vs. oral thing for Anadrol + Var, I gotta push back a bit based on what the actual PK data shows.

I think the differences you're feeling (better strength oral vs. sublingual for Adrol/Var hitting harder sublingually) are likely placebo. The tl;dr:

- These are already optimized for oral use: Both Adrol/Var are 17a-alkylated, so they survive liver's first-pass metabolism. Anavar has ~97% oral bioavailability, so bypassing the gut/liver via sublingual isn't adding much.

(If anything, it could lead to lower overall exposure in some cases.)

- Studies show similar or worse absorption sublingually: For Anavar, a 2020 study [0] on buccal (basically sublingual-ish) in MCT oil found bioavailability of ~62% compared to oral tablets, w/ lower peak levels (44 ng/mL buccal vs. 67 ng/mL oral). Time to peak was the same (~1 hour)

For Adrol, there's no direct data on sublingual, but we can likely assume the same behavior as Var.

- Placebo is huge: BB'ing is full of subjective feels like "damn I'm strong today". There's even a paper that shows placebo effects can mimic AAS gains. (One study had lifters who thought they were on steroids report better performance and even muscle increases.) [1]

If you're expecting sublingual Var to hit like an energy drink, that expectation ALONE could amp you up, even if the blood levels aren't different.

Curious if you've tested liver enzymes or strength metrics objectively?
Anyway, glad it worked out better this round, stay safe with the higher doses!

View attachment 352254

- [0]: Stability of Oxandrolone in Medium-Chain Triglyceride Oil and Pharmacokinetics Following Buccal Administration of the Extemporaneous Formulation in Neonates and Adults - PMC
- [1]: https://www.researchgate.net/public...rength_Training_Do_Steroids_Make_a_Difference

Interesting, thanks for sharing this info.
In the end, steroids are great and as long as I get the desired outcome, I'm happy regardless of technical absorption method lol!
Whether its all going down my throat into the stomach OR some how absorbed sublingually, I can confidently say I do personally 100% get a measurable strength/performance increase in the gym in a quicker and shorter duration of time from anavar preworkout compared to Adrol. #LearningByTheCicle

 

[Banana Joe]

In my 20's used to go out partying and drank my face off while taking tren and 100 mg winstrol daily. Never got bloodwork, never checked blood pressure. Not proud of it. Ashamed of it actually. But that lunacy is what informs my present day approach to harm reduction.

What held me back the in evolution as BB, and while I won't claiming the following were or are extraordinary, it was not not my lack of talent, or worth ethic - it was my unwillingness to recklessly abuse drugs to get bigger.
In hindsight, I would do that part a lot different, because I can't do all these tings anymore, as I could have done them 20 years ago.

In the end, steroids are great

Amen to that.

 

[Photon]

Sounds like you had a solid run with the Adrol this time around, esp. with the Mast helping the water retention.

But on the sublingual vs. oral thing for Anadrol + Var, I gotta push back a bit based on what the actual PK data shows.

I think the differences you're feeling (better strength oral vs. sublingual for Adrol/Var hitting harder sublingually) are likely placebo. The tl;dr:

- These are already optimized for oral use: Both Adrol/Var are 17a-alkylated, so they survive liver's first-pass metabolism. Anavar has ~97% oral bioavailability, so bypassing the gut/liver via sublingual isn't adding much.

(If anything, it could lead to lower overall exposure in some cases.)

- Studies show similar or worse absorption sublingually: For Anavar, a 2020 study [0] on buccal (basically sublingual-ish) in MCT oil found bioavailability of ~62% compared to oral tablets, w/ lower peak levels (44 ng/mL buccal vs. 67 ng/mL oral). Time to peak was the same (~1 hour)

For Adrol, there's no direct data on sublingual, but we can likely assume the same behavior as Var.

- Placebo is huge: BB'ing is full of subjective feels like "damn I'm strong today". There's even a paper that shows placebo effects can mimic AAS gains. (One study had lifters who thought they were on steroids report better performance and even muscle increases.) [1]

If you're expecting sublingual Var to hit like an energy drink, that expectation ALONE could amp you up, even if the blood levels aren't different.

Curious if you've tested liver enzymes or strength metrics objectively?
Anyway, glad it worked out better this round, stay safe with the higher doses!

View attachment 352254

- [0]: Stability of Oxandrolone in Medium-Chain Triglyceride Oil and Pharmacokinetics Following Buccal Administration of the Extemporaneous Formulation in Neonates and Adults - PMC
- [1]: https://www.researchgate.net/public...rength_Training_Do_Steroids_Make_a_Difference

@readalot

Thoughts? I know you mainly use troches?
Is the lower absortion rate due to low exposure time? 5mins?
What about PK profile?

 

[readalot]

@readalot

Thoughts? I know you mainly use troches?
Is the lower absortion rate due to low exposure time? 5mins?
What about PK profile?

AUC vs PK profile. You summed it up nicely. I have posted about it plenty.

Run 25 mg/day troche and administer buccally. Disciplined buccal admin. Do it for 4 weeks. Test what you will.

Repeat with oral admin. Same stuff.

PK profile for buccal done right is night and day vs oral admin.

How could bioavailability/AUC for buccal troche be less than oral in well controlled DOE?

Please don't make any troches with MCT oil. Sublingual inferior to buccal admin on upper gum line in you want to minimize time to Cmax.

Very nice post on sublingual by @ChemBB. Thanks!!

 

[Lt.Dan.]

25mg ED 8weeks (sublingual 15min) 1hour before workout and in the morning on day off. No side effects, strength gains are crazy, weight gains too eat clean and didnt have a lot of water retention but more muscle fullness.

 

[Jaxino]

These are the 2 most known but there’s definitely more people in such high or higher dosages, we may not know them or they just never told it publicly.

What I’m curious about high drol is how is it possible to mess people’s GI at baby dosages of 50mg in bodybuilding world with meticulous diet choices and powerlifters can perform on 8-10K calorie diets with high fats and 200mg+ drol. It’s amazing.

The reality Is that people's genes nowadays suck big time.

I have a friend that needs 7mg Adex a week for 750 Sust a week. And he Is lean and eats clean!!!! Jeez. If he takes 25mg Anadrol his stomach explodes...

People that are healthy and can use moderate amount of PEDs with no worries should go to the church and light a candle everyday.

 

[AlmightyAlpha]

The reality Is that people's genes nowadays suck big time.

I have a friend that needs 7mg Adex a week for 750 Sust a week. And he Is lean and eats clean!!!! Jeez. If he takes 25mg Anadrol his stomach explodes...

People that are healthy and can use moderate amount of PEDs with no worries should go to the church and light a candle everyday.

Your friend doesn't need 7mg adex.... He's just going about his protocol shitty.
I'm sure his cholesterol is tanked now due to that adex. If he has a coach, or any friends with at least an inch of knowledge...they'd help him and explain this ..
Instead of trying to lower estrogen with a compound that does nothing for muscle gain, why not lower the test down to 500 mg and add proviron at 50-75mg daily. It's anabolic and will harden you up plus lower shbg which is a plus and also brin down e2. I bet he'd be in range with 50-75mg a day and at 500mg.