Another good article about MENT. The reduced bone mass means total estradiol + 7⍺-methylestradiol was insufficient. Adding a very little bit of test or using slightly more MENT would have fixed this.
The potent synthetic androgen 7 alpha-methyl-19-nortestosterone (MENT) is resistant to 5 alpha-reductase but is a substrate for aromatase. It may therefore offer selective sparing of the prostate gland while supporting other androgen-dependent tissues. MENT acetate implants were administered for...
pubmed.ncbi.nlm.nih.gov
As an androgen, MENT is about 10x potency of testosterone. That's why the dose should be escalated slowly. Going from 5mg > 25mg/day MENT is equivalent of 350mg > 1750mg test per week!
As an estrogen, 1mg MENT is equivalent to about 2mg of test, when you factor in the rate of aromatization (23% of test), the binding affinity (102% of estradiol, ER transactivation (4x test in a study with estrogen-resistant T47Dco breast CA cells), and resistance of binding to SHBG (the 7⍺-methylestradiol is 100% free, just like the androgen). So 10mg/day MENT will give estrogenicity of about 140mg/wk test. Plus whatever estradiol is made via natural + endogenous testosterone, HCG, etc.
You can see how people get in trouble easily with MENT by getting a vial and dosing it like other AAS ~ 50mg/day. That's going to give the estrogen of about 700mg/wk test, which is AI territory for most people.
On another note, I started OEP's EQ @ 30mg/day on Sept 1. I usually have to dose 12.5mg aromasin 1-2x per week. I know EQ takes a very long time to build up, but I haven't needed aromasin for 9 days now. Unlike primo EQ might actually have a strong AI effect in me... which means it will pair perfectly with MENT. I've only found one other guy (on reddit) who did a MENT + EQ cruise, and apparently it was very successful. I guess I'll be patient #2.
Also added a 15mg/day DHB Sept 1, and my strength has already increased signficantly after being at a plateau for a while. It might be the best compound ever for strength.
Replacing 30mg/day primo with 30mg/day EQ and 15mg/day DHB seems to be a huge win so far. I've run primo several times now and have been less than impressed with it.