RockyP
Member
Yes, another poll.
I've been trouble shooting my TRT+ regimen, playing around with Test dosages and trying to taper / discontinue an AI with recent addition of NPP and neurosis about using Mast / Primo due to low HDL (ironically my Total Chol / HDL and LDL / HDL places me at average risk, though ApoB / ApoA1 has me at 2x average risk).
In my futzing around I went back over some older bloodwork and found that even when I was on Test 300 with no AI and my E2 was 100, I didn't have any typical E2 symptoms. It was at that time that my HRT doc added in Arimidex 1.5 mg weekly. That brought me down into the 30's, but in the same timeframe my HDL fell from 39 to 30. I've since dropped the test to 200, reduced the arimidex to 0.5 mg, and added NPP 150. Subjectively, I feel quite a bit better (NPP just started so it's not in play yet) on the lower test / lower AI. Recent Labs taken before the adjustment on 300 test / 1.5 Arimidex had E2 at 35 and I was feeling some joint pain (non-specific), but otherwise ok. I'll be re-checking bloods in about 4-6 weeks to see what the E2, prolactin levels are on this regimen, but I'm curious where others like to have their E2 live. We seem to sort of ignore the "reference range" on certain labs (i.e. test) when it suits us, but at other times we obsess about being the reference range. I don't think it's ever a great idea to have E2 around 100 like mine was on 300 test with no AI, but I'm wondering if mid / high 40's might be a sweet spot.
Please share your experiences.
I've been trouble shooting my TRT+ regimen, playing around with Test dosages and trying to taper / discontinue an AI with recent addition of NPP and neurosis about using Mast / Primo due to low HDL (ironically my Total Chol / HDL and LDL / HDL places me at average risk, though ApoB / ApoA1 has me at 2x average risk).
In my futzing around I went back over some older bloodwork and found that even when I was on Test 300 with no AI and my E2 was 100, I didn't have any typical E2 symptoms. It was at that time that my HRT doc added in Arimidex 1.5 mg weekly. That brought me down into the 30's, but in the same timeframe my HDL fell from 39 to 30. I've since dropped the test to 200, reduced the arimidex to 0.5 mg, and added NPP 150. Subjectively, I feel quite a bit better (NPP just started so it's not in play yet) on the lower test / lower AI. Recent Labs taken before the adjustment on 300 test / 1.5 Arimidex had E2 at 35 and I was feeling some joint pain (non-specific), but otherwise ok. I'll be re-checking bloods in about 4-6 weeks to see what the E2, prolactin levels are on this regimen, but I'm curious where others like to have their E2 live. We seem to sort of ignore the "reference range" on certain labs (i.e. test) when it suits us, but at other times we obsess about being the reference range. I don't think it's ever a great idea to have E2 around 100 like mine was on 300 test with no AI, but I'm wondering if mid / high 40's might be a sweet spot.
Please share your experiences.
