What did you inject today?

Dam
Nice pens and vial caps
I'm surprised you load up reta even tho it's a weekly shot

You actually prefer pinning once a week? I’m splitting my dose into two shots right now to keep blood levels more stable, but anecdotally, everyone on the board seems to run a different protocol. What's your rationale for the single shot?
 
Me lazy
Pharma trials did once a week

I always figured the pharma trials stuck to once-a-week purely for patient compliance. Their target demographic is mostly gen-pop who probably aren't thrilled about needles. If Lilly told them to pin multiple times a week, trial drop-out rates would probably be huge.

I'm definitely no expert on this, but from what I understand, Reta's half-life is around 6 days. Wouldn't taking the whole weekly dose at once give you a massive peak (and potentially more GI sides) followed by a trough where the hunger comes back right before your next shot?

Just thinking out loud, but since most guys here don't mind pinning anyway, it seems like splitting it into two smaller doses (like E3.5D) would keep blood serum levels way more stable and smooth out the ride. Has anyone else noticed less nausea or better appetite control doing it this way?
 
You actually prefer pinning once a week? I’m splitting my dose into two shots right now to keep blood levels more stable, but anecdotally, everyone on the board seems to run a different protocol. What's your rationale for the single shot?
I do every 5 days, which has been working well for me. At 7 days I could start to feel the effects taper off a bit (things like increased food noise). The only thing to keep in mind is that dosing 5mg every 5 days is similar to dosing 7mg every 7 days.

I think the jury is still out on the most effective dosing protocol.
 
I always figured the pharma trials stuck to once-a-week purely for patient compliance. Their target demographic is mostly gen-pop who probably aren't thrilled about needles. If Lilly told them to pin multiple times a week, trial drop-out rates would probably be huge.

I'm definitely no expert on this, but from what I understand, Reta's half-life is around 6 days. Wouldn't taking the whole weekly dose at once give you a massive peak (and potentially more GI sides) followed by a trough where the hunger comes back right before your next shot?

Just thinking out loud, but since most guys here don't mind pinning anyway, it seems like splitting it into two smaller doses (like E3.5D) would keep blood serum levels way more stable and smooth out the ride. Has anyone else noticed less nausea or better appetite control doing it this way?
Pinning more frequently reduces the peaks, which could limit the effectiveness. As I understand it, some benefits do not kick in until you’ve hit a certain concentration. Admittedly, I am still learning, but this is my understanding and part of my rationale.
 
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