RHR and HRV on Reta/GLPs

[shcidheuddvv]

Hey guys! I'm wondering what strategies, if any, y'all have implemented to mitigate the RHR raising and HRV lowering effects of Reta. 2mg a week has been enough to drop my HRV from 120s to 50s and raise my RHR from 50s to 70s.

 

[Cman90]

The glucagon component in Retatrutide is what sets it apart from Segmaglutide and Tirzepitide. The glucagon competent is responsible for the increased heart rate, which produces a thermogenic effect and increasing daily caloric expenditure. This is what makes it more effective than both Tirz and Segma.

If you don't like it, you could try lowering the dose or switching to another GLP-1.

 

[johnjay06]

Hey guys! I'm wondering what strategies, if any, y'all have implemented to mitigate the RHR raising and HRV lowering effects of Reta. 2mg a week has been enough to drop my HRV from 120s to 50s and raise my RHR from 50s to 70s.

Ivabradine is the only thing that helps with reta rhr for me

 

[Bammdk]

Ivabradine is the only thing that helps with reta rhr for me

But wouldn’t that stop the thermogenic effect?

 

[zneekah]

MOTS-C seems to help me with the pulse

 

[Cman90]

But wouldn’t that stop the thermogenic effect?

Potentially, or reduce it. At that point, might as well take Tirzepitide.

 

[johnjay06]

Probably would be better to run tirz. However, some of the kidney protection benefits that I've read on reta is what keeps me on it.

 

[shcidheuddvv]

Probably would be better to run tirz. However, some of the kidney protection benefits that I've read on reta is what keeps me on it.

Yeah, the glucagon agonism was what originally got me interested, as the last cut I did my RHR dropped just below 40 at the very end and my daily expenditure was nuked. I didn't realize how strong it would be though, so I may have to reserve Reta for cuts, and then stock up on some Triz for general metabolic/cardiovascular health going forward. Hopefully Triz is less harsh on my RHR.

 

[a7las]

I have been running Reta since the end of September. Titrated up to 4mg per week.

My RHR climbed from the 60s to the 70s at first but has since dropped back down into the low 60s.

It never got to a point that concerned me personally and I like the Glucagon component.

Down almost 20lbs