Psychiatrist

[Jin23]

Never SSRIs (I don't think I will ever agree to take these, I am used to depression and don't want to hide it).

This is a really uneducated opinion. Thing is, chronic anxiety is down to a dysregulated HPA axis. There is also a high (neuro) inflammatory state present along with fucked neurobiology which also means fucked neurochemistry. Put together, it's called depression and GAD. Treating GAD (and a depressed neurobiology) should be done with something that "heals" the brain. Something that causes hippocampal neurogenesis, creates new neuronal paths, leads to fear extinction, etc. This is achieved with a) modulating the HPA axis via serotonin HT1a and HT2c receptors and b) TRK-B receptor agonism via BDNF. All of it also leads to lowered inflammation.

Now, I don't know what story you told your psychiatrist, and what kind of a doctor he is, paid, public healthcare, etc., but gabapentin is definitely far from being the first choice and also the best choice to achieve this. If you don't want to take SSRI's, bc you are ideologically against them, you have other options. You can tackle just the BDNF route via cerebrolysine injections coupled with CBT and meditation. You can also add psychadelics. But "antidepressives", be it SSRI's or SNRI's DNRI's, MAOI's,TCA's, Buspirone, Trazadone, etc. etc. are all much much better options. Vortioxetine maybe, that just kills anxiety like nothing else, and in dosages bellow 10mg's, doesn't really work like an SSRI. Trust me, I've taken these drugs and I can say that the effects are eye opening and life changing.

Regarding adhd if left untreated can and often does lead to chronic anxiety. But anxiety also leads to adhd. If you truly have problems with executive functions, serotonin modulating drugs aren't a good option. It's the reason why I can't take them, I can't even read one sentence from a book when I'm on them, as my mind just keeps forget what I'm doing and wanders off. But, you might be different, especially if you don't have problems with thought inhibition in the first place.

Pregabalin, while it's effects are immediate, it doesn't heal the brain as above mentioned drugs do and will lead to dependency. Idk, maybe it will help regulate the hpa axis, haven't looked up studies on it, but again, dependency and bad withdrawal, lots of horror stories online, suggest you read them a bit before you commit to a long term solution.

Reddit - Dive into anything

www.reddit.com

 

[Hightower]

Anxiety can be debilitated and I sure hope you get good care. Don't take advice from strangers on the internet. Be totally transparent with your docs and follow their advice. I know it's hard to put any faith in big pharma. But when we really need it, we have no choice. Good luck to you.

I am sure that it is better to listen to doctors than advice from the Internet. generally safer and more efficient.

 

[hyooge]

This is a really uneducated opinion. Thing is, chronic anxiety is down to a dysregulated HPA axis. There is also a high (neuro) inflammatory state present along with fucked neurobiology which also means fucked neurochemistry. Put together, it's called depression and GAD. Treating GAD (and a depressed neurobiology) should be done with something that "heals" the brain. Something that causes hippocampal neurogenesis, creates new neuronal paths, leads to fear extinction, etc. This is achieved with a) modulating the HPA axis via serotonin HT1a and HT2c receptors and b) TRK-B receptor agonism via BDNF. All of it also leads to lowered inflammation.

Now, I don't know what story you told your psychiatrist, and what kind of a doctor he is, paid, public healthcare, etc., but gabapentin is definitely far from being the first choice and also the best choice to achieve this. If you don't want to take SSRI's, bc you are ideologically against them, you have other options. You can tackle just the BDNF route via cerebrolysine injections coupled with CBT and meditation. You can also add psychadelics. But "antidepressives", be it SSRI's or SNRI's DNRI's, MAOI's,TCA's, Buspirone, Trazadone, etc. etc. are all much much better options. Vortioxetine maybe, that just kills anxiety like nothing else, and in dosages bellow 10mg's, doesn't really work like an SSRI. Trust me, I've taken these drugs and I can say that the effects are eye opening and life changing.

Regarding adhd if left untreated can and often does lead to chronic anxiety. But anxiety also leads to adhd. If you truly have problems with executive functions, serotonin modulating drugs aren't a good option. It's the reason why I can't take them, I can't even read one sentence from a book when I'm on them, as my mind just keeps forget what I'm doing and wanders off. But, you might be different, especially if you don't have problems with thought inhibition in the first place.

Pregabalin, while it's effects are immediate, it doesn't heal the brain as above mentioned drugs do and will lead to dependency. Idk, maybe it will help regulate the hpa axis, haven't looked up studies on it, but again, dependency and bad withdrawal, lots of horror stories online, suggest you read them a bit before you commit to a long term solution.

Reddit - Dive into anything

www.reddit.com

I simply am not in a position in life to take the SSRI, I can't deal with the potential fallout rn, and I do not want to rely on it.
5HTP was magnificent for depression, and I am working on my undermethylation before considering SSRIs, I do not know enough at the moment.

Yeah I am in a mathematical field, I actually feel a bit more interested in the abstract maths etc (lots of small details etc), so I think I am doing ok, I will not abuse the modafinil, and reassess when I am not fucked up.

I am going through a relocation, I don't speak the local language etc. so it is very turbulent atm, but I feel hopeful.

 

[Jin23]

I am sure that it is better to listen to doctors than advice from the Internet. generally safer and more efficient.

His doctor putting him on pregabalin is a really sketchy move. Again, dependency and withdrawal, coupled with the fact what I wrote above about neurogenesis, "brain repair" and add to that that this is his first thing he is taking, ie. the doc doesn't know if he is a non responder to first line medicine (which are ssri's and then some other AD's), as you prescribe those first and only then try more risky drugs (you do not put somebody on potentially addictive, dependency creating drugs). Sketchy, really sketchy. It's easy to suede docs that you are paying, in to giving you what you want. If he went there, already made up his mind about what he wants to use and what not: he probably communicated that to the doc, in one way or the other, and the doc prescribed it to him. I don't know the doc and the situation, but it's a possibility, that's all.

Pregabalin really is either addictive or at the least dependency creating and has a bad withdrawal. Go check reddit how many use pregabalin to get high. C'mon, do it. Even those who just get it prescribed like he did, end up getting high with them often. Not saying OP will do this, but it's a potential. Again, sketchy decision by the doc. I hope he at least gave a lecture on all the dangers off this drug, that he didn't just pass it on like candy, believing the OP that's it's safe ...

 

[Jin23]

I simply am not in a position in life to take the SSRI, I can't deal with the potential fallout rn, and I do not want to rely on it.
5HTP was magnificent for depression, and I am working on my undermethylation before considering SSRIs, I do not know enough at the moment.

Yeah I am in a mathematical field, I actually feel a bit more interested in the abstract maths etc (lots of small details etc), so I think I am doing ok, I will not abuse the modafinil, and reassess when I am not fucked up.

I am going through a relocation, I don't speak the local language etc. so it is very turbulent atm, but I feel hopeful.

It's really hard to abuse modafinil, don't stress about it. You'll get burned out way before anything else. If you can sleep after taking modafinil and if it's helping your exec functions, then that's great. Compared to other adhd meds, moda is one of the least addictive ones.

It's not surprising hearing that 5htp helped. You definitely need serotonin.

 

[Hightower]

His doctor putting him on pregabalin is a really sketchy move. Again, dependency and withdrawal, coupled with the fact what I wrote above about neurogenesis, "brain repair" and add to that that this is his first thing he is taking, ie. the doc doesn't know if he is a non responder to first line medicine (which are ssri's and then some other AD's), as you prescribe those first and only then try more risky drugs (you do not put somebody on potentially addictive, dependency creating drugs). Sketchy, really sketchy. It's easy to suede docs that you are paying, in to giving you what you want. If he went there, already made up his mind about what he wants to use and what not: he probably communicated that to the doc, in one way or the other, and the doc prescribed it to him. I don't know the doc and the situation, but it's a possibility, that's all.

Pregabalin really is either addictive or at the least dependency creating and has a bad withdrawal. Go check reddit how many use pregabalin to get high. C'mon, do it. Even those who just get it prescribed like he did, end up getting high with them often. Not saying OP will do this, but it's a potential. Again, sketchy decision by the doc. I hope he at least gave a lecture on all the dangers off this drug, that he didn't just pass it on like candy, believing the OP that's it's safe ...

What I am reading now is very surprising that the doctor did not take all the side effects into account. Maybe just find a good doctor.

 

[hyooge]

What I am reading now is very surprising that the doctor did not take all the side effects into account. Maybe just find a good doctor.

I like my doc, and my anxiety was clearly insanely high, he did not know how I was functioning.

Also what I forgot to mention is I was smoking weed for a few weeks, this was just to be able to get to places and commitments. I don't abuse it anymore, it was just a rough few weeks and I was still accepting the fact I needed professional help.

Honestly, I feel myself again, checking girl's asses out again etc lol.
The doc just wanted to alleviate sleep issues and anxiety before getting to ADHD/depression issues.

 

[Hightower]

I like my doc, and my anxiety was clearly insanely high, he did not know how I was functioning.

Also what I forgot to mention is I was smoking weed for a few weeks, this was just to be able to get to places and commitments. I don't abuse it anymore, it was just a rough few weeks and I was still accepting the fact I needed professional help.

Honestly, I feel myself again, checking girl's asses out again etc lol.
The doc just wanted to alleviate sleep issues and anxiety before getting to ADHD/depression issues.

Now everyone understands how things are, apparently I put it too harshly in the direction of your doctor.

 

[Jin23]

I like my doc, and my anxiety was clearly insanely high, he did not know how I was functioning.

Also what I forgot to mention is I was smoking weed for a few weeks, this was just to be able to get to places and commitments. I don't abuse it anymore, it was just a rough few weeks and I was still accepting the fact I needed professional help.

Honestly, I feel myself again, checking girl's asses out again etc lol.
The doc just wanted to alleviate sleep issues and anxiety before getting to ADHD/depression issues.

Interesting that weed helps your anxiety. Most people with GAD can't stand weed ...

 

[hyooge]

Interesting that weed helps your anxiety. Most people with GAD can't stand weed ...

I have always loved it.
I feel a lot more emotion on it, sex on weed is magnificent.
Otherwise I am quite blunted (good pun).
Don't show emotion, kinda an asshole on the exterior.

May I ask your credentials or your investment in this kind of data? You seem to be very interested in the "neuropharmaceuticals"/psychiatry.

 

[Jin23]

I have always loved it.
I feel a lot more emotion on it, sex on weed is magnificent.
Otherwise I am quite blunted (good pun).
Don't show emotion, kinda an asshole on the exterior.

May I ask your credentials or your investment in this kind of data? You seem to be very interested in the "neuropharmaceuticals"/psychiatry.

You mean why I'm so invested in this? It started because I'm also adhd and have gad, but have devoted time to try and understand why and how to manage it. Later on I just became interested in the topic and started experimenting, learning.

Most people know more about there cars then their mind. Technically, cognitively and psychological. It's quite funny seeing how people have no idea about what they're doing and why and how they're behaving like they are.

It also helps me a lot in my field of work to understand all of this

 

[Hightower]

Interesting that weed helps your anxiety. Most people with GAD can't stand weed ...

When I tried to smoke weed, I became calmer, but I felt dumber and my brain began to work poorly.

 

[Hightower]

I have always loved it.
I feel a lot more emotion on it, sex on weed is magnificent.
Otherwise I am quite blunted (good pun).
Don't show emotion, kinda an asshole on the exterior.

May I ask your credentials or your investment in this kind of data? You seem to be very interested in the "neuropharmaceuticals"/psychiatry.

Sex on weed? best feeling or how does it feel?

 

[hyooge]

Sex on weed? best feeling or how does it feel?

Yeah man, so when I am dating, I smash 3x a day lol.
So I have a very high sex drive, but as soon as weed hits my system, aphrodisiac... I want to connect more with the woman, I still remember many times where it was so intimate, like girl was legit crying (in a good way lol). Ye man so weed just helps me connect to women emotionally.

 

[Jin23]

When I tried to smoke weed, I became calmer, but I felt dumber and my brain began to work poorly.

Weed negatively impacts the NMDA system, it nukes your working memory and also negatively impacts longer term memory. But it gives you a lot of dopamine in the prefrontal cortex, so you have lot's of focus, better mind body connection, etc. So basically, you're super focused but cant remember shit.

 

[Hightower]

So basically, you're super focused but cant remember shit.

The last sentence is exactly my situation

 

[jJjburton]

His doctor putting him on pregabalin is a really sketchy move. Again, dependency and withdrawal, coupled with the fact what I wrote above about neurogenesis, "brain repair" and add to that that this is his first thing he is taking, ie. the doc doesn't know if he is a non responder to first line medicine (which are ssri's and then some other AD's), as you prescribe those first and only then try more risky drugs (you do not put somebody on potentially addictive, dependency creating drugs). Sketchy, really sketchy. It's easy to suede docs that you are paying, in to giving you what you want. If he went there, already made up his mind about what he wants to use and what not: he probably communicated that to the doc, in one way or the other, and the doc prescribed it to him. I don't know the doc and the situation, but it's a possibility, that's all.

Pregabalin really is either addictive or at the least dependency creating and has a bad withdrawal. Go check reddit how many use pregabalin to get high. C'mon, do it. Even those who just get it prescribed like he did, end up getting high with them often. Not saying OP will do this, but it's a potential. Again, sketchy decision by the doc. I hope he at least gave a lecture on all the dangers off this drug, that he didn't just pass it on like candy, believing the OP that's it's safe ...

The things is ssri and etc, INCREASE anxiety for the first 6-12 weeks, and if your anxiety is already debilitating to where its hard to do things, its not possible to take anymore increased anxiety. Everytime i tried and SSRI it increased my anxiety to the point I have to stop after a week.

Actually i just started microdosing shrooms and going to try a day micro LSD, as SSRI also have withdrawals. I had 8 weeks of a migraine coming off lexapro, and couldnt leave the couch. So the withdrawal from these and gabapentin are the same, the horror stories of withdrawL from ssri and others are just as bad on reddit.

Also SSRI increase restless leg syndrome, which is the most uncomfortabke aspect. So its not possible again for me for that type of medicines.

I am well aware, pregabalin is WAY more addictive and horrible then gabapentin. And being on gabapentin long term has negative side effects so you will have too taper down slowly.

That said the ability to learn to live with anxiety while on gabapentin which also treats Restless leeg syndrome, so it does both for myself.


So when life settles down and now I get comfortble in my new job and have consistancy will be able to taper down gabantin and use psycedlics.

So for myself gabapentin is only a short term answer.

I am really having some great aspects from microdosing. Its been only a short time, but to be anle to rewire the brain sounds unbelievable, and so glad to have learned this.

But its imoportant to do own self work while on these things too. Like mediate and learn coping skills for myself, not just take them and be on the phone. But self heal.

 

[jJjburton]

When I tried to smoke weed, I became calmer, but I felt dumber and my brain began to work poorly.

I go into psycosis on weed. Horrible.

 

[Jin23]

The things is ssri and etc, INCREASE anxiety for the first 6-12 weeks, and if your anxiety is already debilitating to where its hard to do things, its not possible to take anymore increased anxiety. Everytime i tried and SSRI it increased my anxiety to the point I have to stop after a week.

Actually i just started microdosing shrooms and going to try a day micro LSD, as SSRI also have withdrawals. I had 8 weeks of a migraine coming off lexapro, and couldnt leave the couch. So the withdrawal from these and gabapentin are the same, the horror stories of withdrawL from ssri and others are just as bad on reddit.

Also SSRI increase restless leg syndrome, which is the most uncomfortabke aspect. So its not possible again for me for that type of medicines.

I am well aware, pregabalin is WAY more addictive and horrible then gabapentin. And being on gabapentin long term has negative side effects so you will have too taper down slowly.

That said the ability to learn to live with anxiety while on gabapentin which also treats Restless leeg syndrome, so it does both for myself.


So when life settles down and now I get comfortble in my new job and have consistancy will be able to taper down gabantin and use psycedlics.

So for myself gabapentin is only a short term answer.

I am really having some great aspects from microdosing. Its been only a short time, but to be anle to rewire the brain sounds unbelievable, and so glad to have learned this.

But its imoportant to do own self work while on these things too. Like mediate and learn coping skills for myself, not just take them and be on the phone. But self heal.

Not sure from where you came in just now ... But I'm sorry brother, this is quite an uneducated opinion.

The problems you had from ssri's are probably because you started off with a to big of a dose. Starting gradually, like 2.5 mg's of escitalopram (or even less) for the first 4 weeks, or more, what ever feels comfortable, and then increase to 5mg ... is the way to go.

It's also not factually accurate to say that ssri's increase anxiety for the first 6 to 12 weeks. They decrease anxiety, for the first week, then they increase it a bit and then it decreases again. This happens in a matter of 3 to 4 weeks. Again, starting off with a low dose is key.

Same goes for going off ssri's. You don't just take half the dose one day and suffer withdrawal. You take 5% less for a week, then 5% less for the next week, etc. I guarantee, you wont have any withdrawals this way. But if you do, then go at it at an even slower pace.

Microdosing shrooms and acid has it's benefits for sure. But I can almost guarantee, that it wont help in the long run. Microdosing is the next hype, like cbd for example (which works wonders for me, but unfortunately you need to up the dose pretty soon), but is again very unlikely to be a permanent solution. And the rewiring happens at large, trip dosages, not really with microdosing. Mind you, rewiring also happens with ssri's, and it's more likely for it to be a sustainable treatment for people with chronic anxiety. Not everybody has the intellectual and spiritual proves to be able to trip on heavy dosages. But if you do, give it a go, just be careful, start small and gradually build up.

 

[Hightower]

I go into psycosis on weed. Horrible.

My brother is the same, so I am very afraid of smoking.