Progesterone in oil

[bananafeet]

Zero pip for me, likely because the volume is so low. The formula I have is 100mg/ml, and I use 8mg daily. (Rx was higher volume because of a weaker strength of 50mg/ml.) A few times I’ve dosed 25mg without issue to stop mid cycle spotting after missing a dose.

Before being prescribed inj, my oral dose was 300mg, and prescribed dose inj dose is 15mg nightly. That was with estradiol cyp at 2mg/wk.

I’m currently at e cyp 3mg a week and the 8mg progest. It was trial and error finding what worked best; dropped it down to lowest possible to where bleeding was controlled without cycle suppression.

I know people have diff experiences with eo, but my HSCRP has been <0.2mg/l for years, and remains unchanged. If it ever becomes a problem I’d look into the suspension bananafeet mentioned.

Thanks for the write up.

My nipples started aching when I read 3mg of estrodial per week. Holy moly that's a lot.

You don't get bloating or any sides at that dose? Or does the progesterone sort of reduce the sides?

 

[IndividualMan]

Thanks for the write up.

My nipples started aching when I read 3mg of estrodial per week. Holy moly that's a lot.

You don't get bloating or any sides at that dose? Or does the progesterone sort of reduce the sides?

thats womens HRT doses, no?

 

[bananafeet]

thats womens HRT doses, no?

Yeah but it's a lot even for a woman. Like 0.5mg has a massive effect.. obviously depends on the endogenous production

 

[IndividualMan]

Yeah but it's a lot even for a woman. Like 0.5mg has a massive effect.. obviously depends on the endogenous production

really? I thought .5 is about right/ont he higher end for men, with massive positive implications for heart and brain health, but women do have crazy high endogenous E2 production, so idk how much is high for them.

I would guess 4-8x my high end could be about right for them, but sadly I am a labrat, no endocrinologist by trade.

 

[bananafeet]

really? I thought .5 is about right/ont he higher end for men, with massive positive implications for heart and brain health, but women do have crazy high endogenous E2 production, so idk how much is high for them.

I would guess 4-8x my high end could be about right for them, but sadly I am a labrat, no endocrinologist by trade.

Yeah like I said it depends on the endogenous level...

Depends if the stuff you've got is dosed correctly and how quickly it absorbs. Sometimes during perimenopause women over produce estrodial so if you administer small amount it can cause supra physiological levels.

It's pretty amazing how estrodial in women with lowish levels basically plumps them up. Everything gets rehydrated and even the skin instantly gets a soft glow.

Even vaginal estrogens which are converted into estrodial by the tissues have an amazing and instant effect.

It's crazy stuff. The human body is pretty amazing.

I can see how it would have a massive effect on the endothelium and heart.

Edit: sorry for derailing the thread.

 

[IndividualMan]

Depends if the stuff you've got is dosed correctly and how quickly it absorbs.

I always forget people use cyp instead of undecylenate for HRT, that makes a lot of sense now.

glow

yes, its crazy for skin health as well

 

[zmurphy]

It's not, its derived from progesterone which is the closest i could find that was used for pharma.

it'll dissolve.

View attachment 378390

https://pmc.ncbi.nlm.nih.go

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Also explains why the suspension was more tolerable. I've got castor oil based testosterone enanthate in the cupboard. It's real pharma stuff I got prescribed but I refuse to use it. PIPs like a mofo because it's super high in BB.

Progesterone doesn't have an ester so what's the dosing protocol for HRT? Daily dosing during the luteal phase?

No wonder why compliance is so poor.

It's every day, either 14 days on, 14 off or constantly depending on if they still want periods or not. The injectable stuff was originally designed for IVF, to make sure that the implantation "takes" so its not run indefinitely. Most ladies using it for HRT are doing so because they don't tolerate Progesterone orally or as a suppository for whatever reason.

Reading through the forums, ladies like the EO stuff because its super thin, and halves the volume required.