MESO-Rx Sponsor Primal Pharma - US Domestic

Just so I'm following (I see what you mean with wadding through the noise. Its like they are bots used to just shuffle pages)

The vendor has said he’s resold CN oil in the past 1 time, but is saying the newest batches are not CN relabels. When 3rd party testing occurs it hasn’t been consistent with the vendors results/testing.

Setting the inconsistencies aside (which could point to different batches or possible relabels), was there also a GCMS result showing it was EO or evidence that it is indeed CN relabel? I know someone sent a sample in, but I’m not experienced enough reading those reports to catch what stands out.



Primal dropped primo 100 and 200 in late December, claimed it was brewed in house with mig 812. Primal also provided a Jano for the raws as well as a gcms and hplc for the 200 that backed up his claims.

People were immediately skeptical of the 100 because it was dosed much more accurate than the 200 and was selectively omitted from GCMS testing.

@Magenzus then GCMS’d us and it came back different than the 200 and primals other recent testing.

The concern is not necessarily the contents of the primo 100 gcms, but rather, it doesn’t appear to be exactly as claimed and no direct attempt at an explanation has been made.

That’s the jist of it. Your mileage may vary on whether its a significant concern or not.
 
The concern is not necessarily the contents of the primo 100 gcms, but rather, it doesn’t appear to be exactly as claimed and no direct attempt at an explanation has been made.
I haven’t seen much of a clear explanation as to why it’s not what it’s claimed yet (100mg primo in Migoyl). I’ve a couple of vials and am interested. From what I can tell from my inexperienced research on lipids, I don’t see any evidence suggesting it’s not what primal claimed.
 
Primal dropped primo 100 and 200 in late December, claimed it was brewed in house with mig 812. Primal also provided a Jano for the raws as well as a gcms and hplc for the 200 that backed up his claims.

People were immediately skeptical of the 100 because it was dosed much more accurate than the 200 and was selectively omitted from GCMS testing.

@Magenzus then GCMS’d us and it came back different than the 200 and primals other recent testing.

The concern is not necessarily the contents of the primo 100 gcms, but rather, it doesn’t appear to be exactly as claimed and no direct attempt at an explanation has been made.

That’s the jist of it. Your mileage may vary on whether its a significant concern or not.
Thanks for this! Okay. Yeah this tracks.
 
I haven’t seen much of a clear explanation as to why it’s not what it’s claimed yet (100mg primo in Migoyl). I’ve a couple of vials and am interested. From what I can tell from my inexperienced research on lipids, I don’t see any evidence suggesting it’s not what primal claimed.

100
200

It's a pity these GCMS are not done consistently, some reports are really clean, clearly showing the oil type, none of these chemical names...and then you have some without even ba bb or..whatever.

The 200 is MCT, we overlap it with 100 - the same compounds are highlighted in yellow. The green compounds overlap with the ones found in veggie oil.

1769996681921.webp

Just see how clean this china oil report is, really well done...would make life so much easier to identify stuff..well...then you see the ones we have above. it makes a huge difference who runs the gcms at the lab..
 
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100
200

It's a pity these GCMS are not done consistently, some reports are really clean, clearly showing the oil type, none of these chemical names...and then you have some without even ba bb or..whatever.

The 200 is MCT, we overlap it with 100 - the same compounds are highlighted in yellow. The green compounds overlap with the ones found in veggie oil.

View attachment 377075

@Primal_Pharma can you please respond to these discrepancies? You have stated in the past that it’s impossible that this is Chinese oil. Yet these GCMS results are inconsistent with Mig 812.

Make it make sense.
 
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100
200

It's a pity these GCMS are not done consistently, some reports are really clean, clearly showing the oil type, none of these chemical names...and then you have some without even ba bb or..whatever.

The 200 is MCT, we overlap it with 100 - the same compounds are highlighted in yellow. The green compounds overlap with the ones found in veggie oil.

View attachment 377075
@Photon can you infer the strength of the primo - mg/ml from the area % as shown in the report?
 
@Photon can you infer the strength of the primo - mg/ml from the area % as shown in the report?

There;'s already a report

 
100
200

It's a pity these GCMS are not done consistently, some reports are really clean, clearly showing the oil type, none of these chemical names...and then you have some without even ba bb or..whatever.

The 200 is MCT, we overlap it with 100 - the same compounds are highlighted in yellow. The green compounds overlap with the ones found in veggie oil.

View attachment 377075
Since Primal also offers GSO as a carrier oil, is it possible the components highlighted in green are contaminants from reused tubing/glassware/filters?
 
100
200

It's a pity these GCMS are not done consistently, some reports are really clean, clearly showing the oil type, none of these chemical names...and then you have some without even ba bb or..whatever.

The 200 is MCT, we overlap it with 100 - the same compounds are highlighted in yellow. The green compounds overlap with the ones found in veggie oil.

View attachment 377075
They overlap right, but Trininolein and 7-Hexadecenal are both found in Coconut and Palm oils that Migoyl 812 is derived from right? 7-haexadecenal as an oxidation byproduct poossibly from heat in trace amounts (GCMS doesnt quanitfy trace or not as we already discussed), whilst Trininolein is the only C18 found in the ME100, which wouldn't make sense if it contained veg oil (there would be a lot of other compounds).

I feel like im missing something here. How confidently can we say that the presence of Trininolein and 7-Hexadecenal in the ME100 indicates that it contains veg oil or is from china?

I don't see the GCMS as being a perfect report, but inferring it contains veg oil feels a stretch to me (i acknowledge my feeling are irrelevant in the truth of the matter).
 
They overlap right, but Trininolein and 7-Hexadecenal are both found in Coconut and Palm oils that Migoyl 812 is derived from right?

Sure
it could be palm or whatever like you said
just not pure mct
def not 812
812 is approved for IV
you can be sure its tested and not in there

the vendor has already shows a gcms of the oil he uses.
clearly, not the same shit
the comparison made above, was by using this vendor's primo 200 vs 100.

(there would be a lot of other compounds).

the number of compounds is not relevant
a large part of it depends on who's doing the report at the lab
Just see how nicely done this China GCMS is

whereas the gcms done above, don't even have ba/bb...i wouldn't be surprised if more stuff turns up if you redid the test..

I feel like im missing something here. How confidently can we say that the presence of Trininolein and 7-Hexadecenal in the ME100 indicates that it contains veg oil or is from china?

We cant
it may be contamination like what was mentioned above
but then that's a larger problem, because not everything appears on gcms
 
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@Whistles77

The best way to answer your questions would be to send a sealed vial of yours in.

The Primo 100 and 200 supposedly brewed from the same set of raws, do not have the same breakdown.
The Primo 100 does not match the oil the vendor uses.
 
@Whistles77

The best way to answer your questions would be to send a sealed vial of yours in.

The Primo 100 and 200 supposedly brewed from the same set of raws, do not have the same breakdown.
The Primo 100 does not match the oil the vendor uses.
How so? We already have a GCMS of the Primo 100 from @Magenzus. What questions would be answered from repeating it? That told us neither if the oil is chinese, nor that it contains veg oil (but some components showed up on test report). If the hypothesis is that different Jano employees come up with different results, then something if massively F'd at Jano.

I don't understand the hypothesis or design of this experiment. As things stand, although there's lots of interesting questions on the differences between the 100/200 and how the misdosing occured of the 200; for the 100, i don't see anything that really raises alarm bells, just speculation on two line items in what otherwise looks like Migoyl, and could be explained by other means than china/veg oil.

I'd be game if i saw alarm bells and need, but i'm struggling to see it.
 
How so? We already have a GCMS of the Primo 100 from @Magenzus. What questions would be answered from repeating it? That told us neither if the oil is chinese, nor that it contains veg oil (but some components showed up on test report). If the hypothesis is that different Jano employees come up with different results, then something if massively F'd at Jano.

I don't understand the hypothesis or design of this experiment. As things stand, although there's lots of interesting questions on the differences between the 100/200 and how the misdosing occured of the 200; for the 100, i don't see anything that really raises alarm bells, just speculation on two line items in what otherwise looks like Migoyl, and could be explained by other means than china/veg oil.

I'd be game if i saw alarm bells and need, but i'm struggling to see it.

Mig is iv approved and has strict requirements on what's in it. You can see the spec sheet.

The vendor has already shown a GCMS of the oil he uses, it's not even the same oil.

What you're basically saying is that this vendor is using palm oil or poorly refined MCT oil, neither of which are pharma or MIG.

There's enough GCMS in this thread, where the vendor was previously using MCT and then switched to MIG, nether of which you would see what is in the primo 100.
 
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Palm oil is not MCT and neither is IV or pharma grade MCT.

What you're basically saying is that this vendor is using palm oil or poorly refined MCT oil, neither of which are pharma or MIG.
I'm not saying that at all. Don't know where that statement came from. I did mention that the two compounds can be found in Palm and Coconut oil as well as vegetable oil, but that's about as far as my assertion went. I do admit i make the assumption that as Migoyl can be made by fractionating coconut or palm oil that there may be a relationship, however i am not qualified to say.


What I am suggesting (rightly or wrongly) is that trace C16 hexadecanoic acid and Trilinolein might appear in to-spec Migoyl 812. I've tried to find evidence otherwise, but havent been able to.
 
I'm not saying that at all. Don't know where that statement came from. I did mention that the two compounds can be found in Palm and Coconut oil as well as vegetable oil, but that's about as far as my assertion went. I do admit i make the assumption that as Migoyl can be made by fractionating coconut or palm oil that there may be a relationship, however i am not qualified to say.


What I am suggesting (rightly or wrongly) is that trace C16 hexadecanoic acid and Trilinolein might appear in to-spec Migoyl 812. I've tried to find evidence otherwise, but havent been able to.

Mig only contains c8 c10.

There's probably over 15 reports in this thread, you would not see it in any of them.

This vendor does however seem to send out different vials to people, which was I was suggesting you sent yours.
 
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