MESO-Rx Sponsor Primal Pharma - US Domestic

[powdered_toast_man]

I am convinced AIs reduce aromatization and SERMs block or mitgate the effects of e2 at the receptor level.

Hopefully no one is convinced that primo or mast can do this. You dumbasses taking these instead of AIs or SERMs while literally praying they function as AIs or SERMs are imbeciles.

 

[nullandvoid]

No need for faith. It's cause and effect. I've got plenty of labs myself. However it does it.. however individual response.. Primo does suppress, reduce, convert, whatever E2 for me. Pick a different hill.

 

[Magenzus]

No need for faith. It's cause and effect. I've got plenty of labs myself. However it does it.. however individual response.. Primo does suppress, reduce, convert, whatever E2 for me. Pick a different hill.

I agree that Primo/Mast aren’t AIs or SERMs and don’t block estrogen receptors.

But yeah they can still drive E2 down in some guys — indirect aromatase suppression and stronger androgen signal, especially if an AI’s still in the mix. Sometimes even no AI. It does happen 100%.

 

[powdered_toast_man]

I agree that Primo/Mast aren’t AIs or SERMs and don’t block estrogen receptors.

But yeah they can still drive E2 down in some guys — indirect aromatase suppression and stronger androgen signal, especially if an AI’s still in the mix. Sometimes even no AI. It does happen 100%.

50% of the time, it works everytime. Am I right, boyzz?

 

[Athleticfreak]

No need for faith. It's cause and effect. I've got plenty of labs myself. However it does it.. however individual response.. Primo does suppress, reduce, convert, whatever E2 for me. Pick a different hill.

He’s a troll, don’t bother with him. On the same level as Korean Guy

 

[Dmiran84]

50% of the time, it works everytime. Am I right, boyzz?

If you know you know

 

[justanoob]

These are currently available.

I don’t see most of the test he posted here uploaded there yet so I’ll wait till @Primal_Pharma confirms

 

[powdered_toast_man]

He’s a troll, don’t bother with him. On the same level as Korean Guy

You saw me say some bullshit about a source's gear anywhere on this forum?

I'm not fucking trolling. This is going to help someone that really needs to get e2 in check for whatever reason. You assholes are potentionally endangering people.

Truth hurts, huh?

 

[Whistles77]

You saw me say some bullshit about a source's gear anywhere on this forum?

I'm not fucking trolling. This is going to help someone that really needs to get e2 in check for whatever reason. You assholes are potentionally endangering people.

Truth hurts, huh?

I've crashed my e2 with Primo once. It was probably the most miserable few weeks of my life. To be told that primo didn't lower my e2 would have not have helped me when it is quite obvious that Primo was the cause, and low e2 was the affect. I think introducing doubt about that possibility might be potentially endangering people.

Maybe i've missed the nuance in this argument. I don't believe Primo is an AI or a SERM (which some people state) and i accept that the mechanisms that lower e2 are different, but it clearly does lower e2 in many people. Surely there's no doubt about that? Right?

 

[Primal_Pharma]

I don’t see most of the test he posted here uploaded there yet so I’ll wait till @Primal_Pharma confirms

It’s available! Uploading all tests to the site by end of the night!

 

[powdered_toast_man]

I've crashed my e2 with Primo once. It was probably the most miserable few weeks of my life. To be told that primo didn't lower my e2 would have not have helped me when it is quite obvious that Primo was the cause, and low e2 was the affect. I think introducing doubt about that possibility might be potentially endangering people.

Maybe i've missed the nuance in this argument. I don't believe Primo is an AI or a SERM (which some people state) and i accept that the mechanisms that lower e2 are different, but it clearly does lower e2 in many people. Surely there's no doubt about that? Right?

There is doubt about that. Yes. Even if I believe you believe you crashed your e2, I don't believe you crashed your e2 via primo.

Taking AI will always reduce conversion of test to e2. Taking nolva will always block activity at the receptor level.

What does primo always do? No one here will here will even confidently say primo always modulates e2, much less how.

 

[justanoob]

It’s available! Uploading all tests to the site by end of the night!

You’re the man

 

[Whistles77]

There is doubt about that. Yes. Even if I believe you believe you crashed your e2, I don't believe you crashed your e2 via primo.

Taking AI will always reduce conversion of test to e2. Taking nolva will always block activity at the receptor level.

What does primo always do? No one here will here will even confidently say primo always modulates e2, much less how.

So........because i don't understand the mechanism behind primo lowering e2, then primo didn't lower my e2? I think you might be conflating what primo does, against AAS/Meso users' ability to explain the biological process (which we are mostly not educated to do). The two are quite orthogonal and the lack of explanation doesn't negate real exeriences.

Personally, i don't believe that my e2 suddenly dropped to zero the first time i took primo, when it had never happened before. Sure correllation doesn't imply causation, but at some point i also don't think some other magic happened that im unaware of that measurably dropped my e2.

I think the doubt might be limited to you, my friend. That's OK. You're allowed to believe what you want to believe. I stand in the camp of play careful with Primo because fucking your e2 will make you miserable.

Hope you don't think that makes me an asshole endangering people.

 

[Ateam2023]

There is doubt about that. Yes. Even if I believe you believe you crashed your e2, I don't believe you crashed your e2 via primo.

Taking AI will always reduce conversion of test to e2. Taking nolva will always block activity at the receptor level.

What does primo always do? No one here will here will even confidently say primo always modulates e2, much less how.

How can you say that it doesn't work to help lower E2 when there's several people that say that it does ? (Through BLOODWORK no less) Primo doesn't aromatize to estrogen, but can functionally lower estrogenic activity for many users, maybe it doesn't work for you, that's not to say it doesn't work for somebody else, everybody responds differently to certain things for you to outright say that it doesn't is just stupidity at its finest, you're always on here having some kind of confrontation with somebody, I think you have a closed mind. Why don't you you STFU

 

[AlexDavis43]

There is doubt about that. Yes. Even if I believe you believe you crashed your e2, I don't believe you crashed your e2 via primo.

Taking AI will always reduce conversion of test to e2. Taking nolva will always block activity at the receptor level.

What does primo always do? No one here will here will even confidently say primo always modulates e2, much less how.

How can you say that it doesn't work to help lower E2 when there's several people that say that it does ? (Through BLOODWORK no less) Primo doesn't aromatize to estrogen, but can functionally lower estrogenic activity for many users, maybe it doesn't work for you, that's not to say it doesn't work for somebody else, everybody responds differently to certain things for you to outright say that it doesn't is just stupidity at its finest, you're always on here having some kind of confrontation with somebody, I think you have a closed mind. Why don't you you STFU

that doesn't seem to far off from what the toast man said

primo might lower E2 for some people but not others

No one here will here will even confidently say primo always modulates e2

[emphasis/bold added is mine, for context]

 

[dcfreak]

Everyone is different. Only taking 500 test my estrogen was 58. Added 300 Primo and it was 12.

Not sure how this is even a debate.

 

[oldage]

Sh

Shut the fuck up already. You could have done all of that and it still wouldn't mean fucking dick.

You don't understand what facts are, nor how science works. You probably believe in ghosts and have evidence of that, too.

"Sounds like you bought fake primo..." are you really this fucking retarded? I guess you are if you've spent thousands on bloodwork like a fucking asshole

Rage bait

 

[Whistles77]

that doesn't seem to far off from what the toast man said

primo might lower E2 for some people but not others



[emphasis/bold added is mine, for context]

I'm not convinced the emphasis on "always" is important. He literally just told me he didn't believe primo crashed my e2.

 

[TheDuderino85]

omg the primo lowers e2 and mast is SERM BS just wont fucking die. even though Derek hasnt updated his channel in years, the shit just won't die.

Primo absolutely lowers e2 in MOST people, not all. There's always exceptions to everything but this is the general consensus.

Also. I have labwork to prove it, as I love Primo with Test, not MPMD

 

[oldage]

You saw me say some bullshit about a source's gear anywhere on this forum?

I'm not fucking trolling. This is going to help someone that really needs to get e2 in check for whatever reason. You assholes are potentionally endangering people.

Truth hurts, huh?

What u believe to be true other people dont need to believe. Especially when there is plenty of evidence supporting these compounds not only lower E2 but fundamentally change people's biological response to testosterone and permanently lowering E2 production with long term use. Imagine that.

But the concern u are claiming to have for anyone starting to use gear should be realized. If people are new and are having issues with E2, AI's are the most proven and effective way to immediately lower it. But they still have to figure out how much to use, how often, and how it effects them individually. There is a learning curve to it all. And guess what, those "expensive" blood tests are the best way we have to collect data points to adjust these medications in a healthy and timely manner.

Of course this is also what you would do with Primo or EQ. But for those new guys you will want to know how much AI to take if you have to bail on the EQ or Primo.

#harmreduction #ragebait #unc