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I am convinced AIs reduce aromatization and SERMs block or mitgate the effects of e2 at the receptor level.

Hopefully no one is convinced that primo or mast can do this. You dumbasses taking these instead of AIs or SERMs while literally praying they function as AIs or SERMs are imbeciles.
 
No need for faith. It's cause and effect. I've got plenty of labs myself. However it does it.. however individual response.. Primo does suppress, reduce, convert, whatever E2 for me. Pick a different hill.
I agree that Primo/Mast aren’t AIs or SERMs and don’t block estrogen receptors.

But yeah they can still drive E2 down in some guys — indirect aromatase suppression and stronger androgen signal, especially if an AI’s still in the mix. Sometimes even no AI. It does happen 100%.
 
He’s a troll, don’t bother with him. On the same level as Korean Guy
You saw me say some bullshit about a source's gear anywhere on this forum?

I'm not fucking trolling. This is going to help someone that really needs to get e2 in check for whatever reason. You assholes are potentionally endangering people.

Truth hurts, huh?
 
You saw me say some bullshit about a source's gear anywhere on this forum?

I'm not fucking trolling. This is going to help someone that really needs to get e2 in check for whatever reason. You assholes are potentionally endangering people.

Truth hurts, huh?
I've crashed my e2 with Primo once. It was probably the most miserable few weeks of my life. To be told that primo didn't lower my e2 would have not have helped me when it is quite obvious that Primo was the cause, and low e2 was the affect. I think introducing doubt about that possibility might be potentially endangering people.

Maybe i've missed the nuance in this argument. I don't believe Primo is an AI or a SERM (which some people state) and i accept that the mechanisms that lower e2 are different, but it clearly does lower e2 in many people. Surely there's no doubt about that? Right?
 
I've crashed my e2 with Primo once. It was probably the most miserable few weeks of my life. To be told that primo didn't lower my e2 would have not have helped me when it is quite obvious that Primo was the cause, and low e2 was the affect. I think introducing doubt about that possibility might be potentially endangering people.

Maybe i've missed the nuance in this argument. I don't believe Primo is an AI or a SERM (which some people state) and i accept that the mechanisms that lower e2 are different, but it clearly does lower e2 in many people. Surely there's no doubt about that? Right?
There is doubt about that. Yes. Even if I believe you believe you crashed your e2, I don't believe you crashed your e2 via primo.

Taking AI will always reduce conversion of test to e2. Taking nolva will always block activity at the receptor level.

What does primo always do? No one here will here will even confidently say primo always modulates e2, much less how.
 
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