Ghoul
Member
That’s more like -1, which is within “normal” “-2 to +2” range.
IGF is lower than 75-85% of peers.
IGF is lower than 75-85% of peers.
MESO-Rx
Anabolic Steroids
Post up your Natty IGF-1 Level
- Thread starter malfeasance
- Start date
Based on my z score, the plan is to slowly titrate up to 6 IU/d operating on the premise of 1 IU -> ~ 0.5 increase in z score. Will recheck IGF in about a month. Any advice on titration speed?
Zscore from quest was 2.3 for the 385 reading. Forgot to add that to my original post
malfeasance
Member
My 83 (see first post of thread) is a Z score of -1.0 . . . a negative 2 must be very low, indeed.
I always found two standard deviations on either side to be a very wide range to be considered "normal." If that were IQ, we would be looking at folks with a 70 IQ (2 SD below) and 130 IQ (2 SD above). Only a little over 2% of the population has above or below those levels of intelligence. Nobody would call either person with 70 or 130 IQ "normal" in intelligence. You probably would not want to hire a 70 IQ individual to do anything more than very simple tasks. If you take 100 persons at random, only 2 are likely to be at this IQ or below. If you went to a school with 1000 students, the poorest performing 20 or so, including special education, is who we are talking about at that level or below.
I am not sure I would ever want my IGF-1 to be at the special ed level.
malfeasance
Member
Borderline genius IGF-1 level!
Ghoul
Member
It reminds of TRT “normal”.
“Yea you’re in the bottom 1%, but that’s in range no test for you”.
And just like TRT, a minority of specialists recognize even if not technically below the normal range, if there are symptoms it’s worth treating.
It’s called:
Adult Growth Hormone Insufficiency (AGHI) or
Functional / Relative Growth Hormone Deficiency
Diagnosed by a Z score below -0.5 and one or
more:
- Fatigue, low energy
- Increased fat mass (especially visceral fat)
- Reduced muscle mass and strength
- Poor exercise recovery
- Low mood or cognitive “fog”
- Reduced bone density
- Low-normal IGF-1 for age
- “Normal” GH stimulation test but blunted response
nxckf
New Member
So I have a -1 Z Score and all of the following symptoms you listed. Would it be worth trying GH to see if symptoms improve?
If only that was natty. Unfortunately I had to use Tesa/IPA to achieve a borderline genius haha
Ghoul
Member
Personally I would.
Are you more like the guy on the left or right?
As long as you understand the responsibility and risks that come along with it.
That said, like self administered TRT for those who used to be routinely denied (before the proliferation of enlightened clinics), the payoff in improved quality of life could change your world. That’s not an exaggeration based on clinical results for those diagnosed with adult GH deficiency. There’s every reason to believe that just like hypogonadism is strictly defined by testosterone numbers, there are those with a GH level that’s “too low for them”, and symptomatic, who benefit from hormone replacement (or “optimization”.
Just remember, because too many don’t seem to grasp this:
It’s not take a dose = everything suddenly gets better or it means it doesn’t work.
It takes time for the most profound improvements to develop. It’s an investment.
But for those who put in the time and effort, I get the impression most never want to go back.
songsofpyramids
Member
I’m -0.1 zscore and going above 1 feels real good to me.
nxckf
New Member
I had no clue about those other symptoms. I have high LDL and low HDL. Bone pain during certain lifts, activities, and almost all of the other symptoms. I’ll have to update the thread after a couple months of being on. Hopefully things are better for me by then.
Mushy404
Member
In freedom units that's ~82 ng/mL - 38 years old.
Now taking 4iu rHGH
Ghoul
Member
Think 6 months for undeniable change. If you aren’t prepared to get enough and stick to it for that long don’t bother. Before then it’s all subtle. One day you notice nails are thicker and shiny, breathing’s deeper, brain fog’s clearing, slowly your deep gut softens and is retracting, skin smoother etc.
It’s funny, for all of GH’s broad popularity here, you could read 1000 posts and only come away with the vaguest sense of what it actually does, yet so many become believers and permanent users. It’s because it’s subtle and profound at the same time, Difficult to put your finger on the benefits other than reverences to helping to rid you of some body fat, but it’s much more than that,
This older paper covers it very well. Going into depth about the benefits such as increased exercise capacity and nutrient metabolism (ie “I could eat anything when I was 18”). After its publication establishment medicine spent the next couple of decades pretending rHGH improves none of these things. “What? Improved skin from rHGH? Never heard of that…”. A massive gaslighting campaign that continues to this day, arising out of the moral panic medicine has over anything that “enhances” instead of just “fixes” human biology. Fear of a stampede to “the fountain of youth”.
(QoL = Quality of Life)
(COGHD = Childhood onset GH deficiency)
(AOGHD = Adult onset GH deficiency)
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