Post up your Natty IGF-1 Level

[hankreal]

Just got my igf back after running 2.5 iu nightly for two weeks. Igf was 308 and z score was 1.6 at 30 years old. I'm upping my dosage to 3.5 and gonna test again sometime. My natty was 205. Mainly upping my dosage to see if I can improve sleep. My sleep is slightly boosted now, but I'm greedy. I got some amazing naps and sleep on 4 iu, but I wanted to ease into it and not push without my igf data. Thanks to @Ghoul for all the info around igf and what not.

 

[Ghoul]

Just got my igf back after running 2.5 iu nightly for two weeks. Igf was 308 and z score was 1.6 at 30 years old. I'm upping my dosage to 3.5 and gonna test again sometime. My natty was 205. Mainly upping my dosage to see if I can improve sleep. My sleep is slightly boosted now, but I'm greedy. I got some amazing naps and sleep on 4 iu, but I wanted to ease into it and not push without my igf data. Thanks to @Ghoul for all the info around igf and what not.

Glad you found it useful.

I’m happy I was able to settle the question over minimizing risk with long term use in my mind too.

Acromegaly, the biggest risk from GH, and the same process that underlies the theoretical increased cancer risk, can only occur with supraphysiological systemic IGF-1.

If your liver was so messed up 20iu / day resulted in a IGF-1 of 100, you’ll never develop acromegaly. (Maybe diabetes lol, but not acromegaly or increased cancer risk).

And if anyone’s wondering, local IGF-1 production in muscle, which increases with rHGH dose, even with low levels of endocrine IGF-1 (liver produced / systemic), cannot cause acromegaly either. Not enough IGF-1 can “escape” muscle tissue to cause acromegaly.

 

[explodingHeart]

Glad you found it useful.

I’m happy I was able to settle the question over minimizing risk with long term use in my mind too.

Acromegaly, the biggest risk from GH, and the same process that underlies the theoretical increased cancer risk, can only occur with supraphysiological systemic IGF-1.

If your liver was so messed up 20iu / day resulted in a IGF-1 of 100, you’ll never develop acromegaly. (Maybe diabetes lol, but not acromegaly or increased cancer risk).

And if anyone’s wondering, local IGF-1 production in muscle, which increases with rHGH dose, even with low levels of endocrine IGF-1 (liver produced / systemic), cannot cause acromegaly either. Not enough IGF-1 can “escape” muscle tissue to cause acromegaly.

IGF output will be massively different for dieting down in single digits vs bulking or maintenance, right?

So we should keep context and mine and test under both conditions?

 

[Moose]

My labs came back with a number of 241. My labs reference range for a 54 year old male is 71-255. I was considering starting IGF-LR3 peptides. But since I'm at the upper range of my reference range, should I be concerned about my number being too high?

 

[screamingeagle]

I'm at 139. Going to start CJC/Ipa.

 

[brutalbuilt]

blood test only test for serum... igf in serum is useless you want igf in muscle

 

[screamingeagle]

blood test only test for serum... igf in serum is useless you want igf in muscle

Tell me more about this. Is intramuscular IGF test available? My goal is to avoid supraphysiological levels and the associated issues.

 

[Ghoul]

My labs came back with a number of 241. My labs reference range for a 54 year old male is 71-255. I was considering starting IGF-LR3 peptides. But since I'm at the upper range of my reference range, should I be concerned about my number being too high?

Increlex has acromegaly warnings. LR3 hits IGF-1 receptors too but it doesn’t get picked up very well on IGF-1 tests. So you’re flying blind. You have some leeway, another ~60 before you reach Z 3.

For a short term experiment it ought to be ok ,

 

[brutalbuilt]

Tell me more about this. Is intramuscular IGF test available? My goal is to avoid supraphysiological levels and the associated issues.

only way to test is if your willingly to get a biopsy and let them cut a piece of your muscle out to test

 

[Jemifus]

Increlex has acromegaly warnings. LR3 hits IGF-1 receptors too but it doesn’t get picked up very well on IGF-1 tests. So you’re flying blind. You have some leeway, another ~60 before you reach Z 3.

For a short term experiment it ought to be ok ,

Is z-score just a short hand way of seeing how far out of range you are? Ie if I get an IGF-1 test that doesn't give a z-score, is it easily calculable using my IGF level and my age?

Answering the thread question: 106ng/ml natural, age 50

 

[Ghoul]

Is z-score just a short hand way of seeing how far out of range you are? Ie if I get an IGF-1 test that doesn't give a z-score, is it easily calculable using my IGF level and my age?

Answering the thread question: 106ng/ml natural, age 50

Z-score isn’t a fixed age/IGF formula because every lab uses a different assay to measure IGF-1.

A 150 on labcorp’s IGF-1 isn’t the same as Quest’s 150. As crazy as that sounds, it means the most accurate measurement is based on models made up of tens of thousands of test results from their lab to come up with where you are “relative” to them.

“Normal” Z range is -2 to +2

0 is the mean for other people of the same age and sex.

Negative is below average.

Positive is above average.

Lower than -2 or above +2 is outside the physiological range and if it’s natty, represents some kind of problem.

If you don’t have a Z-score, we can roughly calculate it using your IGF-1 and the range the lab provides on the report.

 

[KOArtist]

Mine ranged from 185-215ish natty, haven’t seen under 250 with gh

 

[Ghoul]

Mine ranged from 185-215ish natty, haven’t seen under 250 with gh

Age and lab and I can give you close enough Z

 

[KOArtist]

Age and lab and I can give you close enough Z

51 now! Expecting to be maybe 260-275 this time around if I’m guessing. Labcorp lately and on 12/22, but a couple others were Sonora