How potently does GH elevate blood sugar / risk diabetes?

[Galileo]

I am aware that very significant GH use can cause high BS, diabetes

My question is how potent is GH - generally speaking - in terms of elevating blood sugar? How much a concern is it for low doses, like 2-3 units?
My units I mean real GH from big pharma. Not generic or chinese or something, but the real deal

Does 2 units per day elevate blood sugar a lot as to cause concern?
...when is it an issue?

I hear some people using 4-10 units per day so wondering what the proportions are in all these

(I don't want diabetes)

 

[alecutheman]

Depends on the person in my experience, get a glucose meter and keep track of your fasting glucose values each morning and you'll have your answer.

 

[AlexDavis43]

I am aware that very significant GH use can cause high BS, diabetes

My question is how potent is GH - generally speaking - in terms of elevating blood sugar? How much a concern is it for low doses, like 2-3 units?
My units I mean real GH from big pharma. Not generic or chinese or something, but the real deal

Does 2 units per day elevate blood sugar a lot as to cause concern?
...when is it an issue?

I hear some people using 4-10 units per day so wondering what the proportions are in all these

(I don't want diabetes)

I don't think 2-3 IU/d would move the glycemic needle too much.

I use 10 IU/d and employ some preventative anti-hyperglycemics like berberine and empagliflozin. Also do cardio and a low carb diet. Seems to maintain insulin sensitivity fairly well.

 

[Demondosage]

More than ppl think

 

[RekTest]

4iu (along with being a fat shiii) put my a1c at 5.6.

No idea what it is now, as I run 20iu but Im on a heeeavy dose of Tirz that is aiding in controlling the GH, along with being waaay down in weight

 

[GeneLifts]

Be honest already diabetic so I am already on insulin so why I did not care to jump on hgh

 

[Galileo]

Just to be clear, if doing mild-moderate GH and only periodically/cycled, is the insulin resistance reversible upon cessation? I mean does the body largely go back to normal, provided you didn't become diabetic...

 

[29trt]

Just to be clear, if doing mild-moderate GH and only periodically/cycled, is the insulin resistance reversible upon cessation? I mean does the body largely go back to normal, provided you didn't become diabetic...

Even if you become diabetic insulin sensitivity can be restored with diet and exercise... But you will not be able to maintain a weight that is not natural to you.... Be it at 10% fat or 20.
Perhaps on a modified keto diet you might be able to maintain a higher body weight...

 

[egruberman]

How much a concern is it for low doses, like 2-3 units?

None.

Get a glucose meter. I like the precision xtra. My last HbA1C was 5.2 on 6iu/day. Presently on 10iu a day. Fasting BG is <90mg/dL. I believe my last HbA1C prior was 4.9. That could be attributed to less cardio, GH or any number of things. Regardless, I'm in good shape, which I think is attributable to running a GLP1 RA even when bulking.

Point being, I'm fine, for reasons, but you may not be, so implement the necessary metrics to know if you have a problem and the necessary interventions if problems arise.

Just to be clear, if doing mild-moderate GH and only periodically/cycled, is the insulin resistance reversible upon cessation? I mean does the body largely go back to normal, provided you didn't become diabetic...

Yes, provided that the lifestyle factors are under control. That is a reasonable diet and sufficient exercise.

 

[alecutheman]

For another anecdote, I'm currently running 20iu split AM/PM and fasting glucose is in the 80s (mg/dL). Could be better if I did more cardio, but I eat healthy and I'm currently 13.5% bf so I'm still getting away with it. I will still be checking fasting BG daily.

 

[29trt]

None.

Get a glucose meter. I like the precision xtra. My last HbA1C was 5.2 on 6iu/day. Presently on 10iu a day. Fasting BG is <90mg/dL. I believe my last HbA1C prior was 4.9. That could be attributed to less cardio, GH or any number of things. Regardless, I'm in good shape, which I think is attributable to running a GLP1 RA even when bulking.

Point being, I'm fine, for reasons, but you may not be, so implement the necessary metrics to know if you have a problem and the necessary interventions if problems arise.



Yes, provided that the lifestyle factors are under control. That is a reasonable diet and sufficient exercise.

Are you in a surplus , maintaining or deficit?
This makes a HUGE difference when we are talking about insulin resistance especially on GH....
And without serum insulin levels bg numbers are kind of useless

 

[Galileo]

29rt, just to be clear, bulking worse for insulin resistance?

 

[29trt]

29rt, just to be clear, bulking worse for insulin resistance?

Yeah ... "Bulking" with or without GH is going to be worse for insulin resistance.... Gh makes the issue worse especially if you are dirty bulking .
Guys with no genes for diabetes are going to be okay even after years of GH abuse.,the lucky ones.

 

[Eddie.]

Today i got my latest labs which actually i went for a follow up e2 to see if it raised since EQ had crashed it some weeks ago and check DHEA because i forgot it last time.

I don't have a blood sugar device, i never bothered to buy one since i had no plans using insulin. I asked for a FBG and apparently it came out bad, at 102.

3 weeks ago when i did the full panel FBG was 80, insulin 2,5 and HbA1c 4,6. Pretty happy with those values, although for this test i had skipped intentionally HGH dose of the previous night which is 8 IU bolus.

In the latest test i wasn't planning to check for blood sugar and i went 9 hours after taking 8 IU.

I'm on reta and in training days where carbs are higher I'm taking berberine too. Is this something to stress about? My insulin sensitivity apparently is good, fasted insulin and HbA1c are both good, only the fasted sugar is high.

I had seen a video of John Jewett i believe saying that around a 100 FBG when taking HGH pre bed is not alarming, it's expected to be higher than normal and if you stop GH or change protocol it gets back to normal, like it's not a permanent resistance thing that needs too much addressing, something like that..i maybe misquoted some words.

Thing is HGH doesn't help me to sleep and i wouldn't mind change timing, but from the moment I wake up i start eating after 30-60 minutes every couple hours and i don't know how i could make it work dosing it in the mornings.

 

[AlexDavis43]

Is this something to stress about?

nope

 

[zneekah]

Thing is HGH doesn't help me to sleep and i wouldn't mind change timing, but from the moment I wake up i start eating after 30-60 minutes every couple hours and i don't know how i could make it work dosing it in the mornings.

I do AM (GH doesnt help me sleep either) and I have a similar issue with breakfast timing, and been considering doing IM for this reason. I dont do GH for mass anyway but more for recovery, healing, fat burn so if IM means a little less IGF/muscle building but more GH effects thats probably way to go for me.

Thinking IM should make the need for a fasted post injection window shorter?

 

[BigDadd7]

Today i got my latest labs which actually i went for a follow up e2 to see if it raised since EQ had crashed it some weeks ago and check DHEA because i forgot it last time.

I don't have a blood sugar device, i never bothered to buy one since i had no plans using insulin. I asked for a FBG and apparently it came out bad, at 102.

3 weeks ago when i did the full panel FBG was 80, insulin 2,5 and HbA1c 4,6. Pretty happy with those values, although for this test i had skipped intentionally HGH dose of the previous night which is 8 IU bolus.

In the latest test i wasn't planning to check for blood sugar and i went 9 hours after taking 8 IU.

I'm on reta and in training days where carbs are higher I'm taking berberine too. Is this something to stress about? My insulin sensitivity apparently is good, fasted insulin and HbA1c are both good, only the fasted sugar is high.

I had seen a video of John Jewett i believe saying that around a 100 FBG when taking HGH pre bed is not alarming, it's expected to be higher than normal and if you stop GH or change protocol it gets back to normal, like it's not a permanent resistance thing that needs too much addressing, something like that..i maybe misquoted some words.

Thing is HGH doesn't help me to sleep and i wouldn't mind change timing, but from the moment I wake up i start eating after 30-60 minutes every couple hours and i don't know how i could make it work dosing it in the mornings.

Lots of people take it in the morning and don't fast for a few hours. You just lose some of that ideal lypolisys window. I did that for a while until I made the decision to not eat for the first three hours.

 

[Eddie.]

nope

Thanks, that's what i was hoping to hear!

I do AM (GH doesnt help me sleep either) and I have a similar issue with breakfast timing, and been considering doing IM for this reason. I dont do GH for mass anyway but more for recovery, healing, fat burn so if IM means a little less IGF/muscle building but more GH effects thats probably way to go for me.

Thinking IM should make the need for a fasted post injection window shorter?

Man, that thing with the GH release time and administration around meals is messing with my brain. I won't take it IM and I'm too lazy to shoot smaller dosages 2-3 times a day. So it's either subc all pre bed or all subc first thing in the morning. I'll probably stick with what I'm doing.

Lots of people take it in the morning and don't fast for a few hours. You just lose some of that ideal lypolisys window. I did that for a while until I made the decision to not eat for the first three hours.

This could work if food is not high, genetically my appetite is at its worst in the mornings, i could do well for 6 hours fasted but currently I'm having 600gr carbs and most likely I'll need to go higher in the following weeks. It won't be possible to stretch all my meals in a more narrowed timeframe.

 

[safc49]

Hopefully someone more knowledgeable than me can see this thread but I believe retatrutide is a good peptide to run alongside hgh for that reason

 

[Eddie.]

Hopefully someone more knowledgeable than me can see this thread but I believe retatrutide is a good peptide to run alongside high for that reason

Already running 3,5mg a week