How long does exo. GH suppress natural release?

[Wunderpus]

U

I can't find any reason to use GH and PEP simultaneously as the intent would be some form of synergy much like it would be combining different AAS. But AAS exert their effects on the target organ (SKM) almost exclusively and that's one huge difference as there are several mechanisms and or pathways that may be influenced (at least theoretically) by combining AAS.

PEPs or secretagogues effect PITUITARY GH secretion and in doing so RAISE somatotropin levels which limit their benefit to physiologic GH levels or close to it.

It's for this reason I see no advantage of combining supplemental GH with PEPS. In fact I doubt PEPs have any utility when running GH bc their efficacy is likely markedly blunted by the HIGH somatropin AND IGF levels induced by exogenous GH

Wanna use PEPs perhaps the best interval is POST-CYCLE but there's ONE problem here also and that is GH IS SYNERGISTIC with TT and the low TT levels during the post-cycle interval should give one pause there also.

Yea the PEP studies are limited for several reasons namley the availability of FDA approved drugs used to raise GH. Research is EXPENSIVE and why would any Big Pharma company invest in research when another company already has one or two products on the market.

I last question for you, for now (I want to maximize my copay doc).

What're your thoughts on splitting the dose of GH vs. doing it all in one shot? I figure if you're running 3iu or less a day, one shot is sufficient. But, for those who are running significantly higher, do you think splitting the dose throughout the day will yield better effects?

Thanks!

 

[mands]

U

I last question for you, for now (I want to maximize my copay doc).

What're your thoughts on splitting the dose of GH vs. doing it all in one shot? I figure if you're running 3iu or less a day, one shot is sufficient. But, for those who are running significantly higher, do you think splitting the dose throughout the day will yield better effects?

Thanks!

I've touched base on this many times. One shot will yield a higher IGF-1 level and it will also reach that higher level quicker.

In exchange one shot most likely will give you worse sides than splitting them.

mands

 

[Wunderpus]

I've touched base on this many times. One shot will yield a higher IGF-1 level and it will also reach that higher level quicker.

In exchange one shot most likely will give you worse sides than splitting them.

mands

You don't think it would be "better" to mimic your GH pulses, but with higher exo. doses?

 

[mands]

You don't think it would be "better" to mimic your GH pulses, but with higher exo. doses?

I personally DO NOT think so. If I was deficient and using it as a specific replacement therapy then I may reconsider.

mands