High IGF1 result from a low amount of HGH

[bananafeet]

Anyone else have a similar result? I've been injecting daily 2iu of HGH.

My IGF1 result after a few months:
Sex : Male
Age = 30-39 years
IGF-1 measured = 351.14503816794 ng/ml (46 nmoles/L)
95 percentiles limits using LMS estimation based on 55 individuals : from 110 to 263
The measured IGF-1 is over the upper limit
SDS score = 3.5
Apparently this is way to high. My natty levels before TRT and HGH were:
GF-1 measured = 137.40458015267 ng/ml (18 nmoles/L)
95 percentiles limits using LMS estimation based on 55 individuals : from 110 to 263
The measured IGF-1 is between the lower and upper limits.
SDS score = -1.1

Is this level high enough to artificially raise eGFR? My creatinine recently dropped quite a lot, from out of range (119nmol/1.35mg/dl) to 100nmol/1.13mg/dl which is around my baseline.

I've stopped the HGH for now. I'm doing a Urine ACR and creatinine test next month to confirm my kidneys are ok.

 

[Ateam2023]

Anyone else have a similar result? I've been injecting daily 2iu of HGH.

My IGF1 result after a few months:
Sex : Male
Age = 30-39 years
IGF-1 measured = 351.14503816794 ng/ml (46 nmoles/L)
95 percentiles limits using LMS estimation based on 55 individuals : from 110 to 263
The measured IGF-1 is over the upper limit
SDS score = 3.5
Apparently this is way to high. My natty levels before TRT and HGH were:
GF-1 measured = 137.40458015267 ng/ml (18 nmoles/L)
95 percentiles limits using LMS estimation based on 55 individuals : from 110 to 263
The measured IGF-1 is between the lower and upper limits.
SDS score = -1.1

Is this level high enough to artificially raise eGFR? My creatinine recently dropped quite a lot, from out of range (119nmol/1.35mg/dl) to 100nmol/1.13mg/dl which is around my baseline.

I've stopped the HGH for now. I'm doing a Urine ACR and creatinine test next month to confirm my kidneys are ok.

you could also include a cystatin c test for kidney function, its how i caught my early stage ckd,

 

[Elektrobot]

include a cystatin c test for kidney function

This. Get a cystatin c test

And for the cause of the high igf levels, when are you taking it, whats your estradiol level, and how much are you eating

Shooting GH during times of high caloric intake increases the igf conversion, especially if you are taking it non-fasted. Higher estradiol also contributes to higher igf conversion.

 

[bananafeet]

My cystatin c was 1.05mg/L on 6/6/25. This was measured at the same time my creatinine was elevated at 111.

Everything on the latest blood test was perfect basically.

I saw my GP and he ordered the cystatin C and Urine ACR 3 months from the last cystatin C test.

 

[bananafeet]

This. Get a cystatin c test

And for the cause of the high igf levels, when are you taking it, whats your estradiol level, and how much are you eating

Shooting GH during times of high caloric intake increases the igf conversion, especially if you are taking it non-fasted. Higher estradiol also contributes to higher igf conversion.

My last E2 was 298 pmol and test was 57.7nmol on 28/08/25. These were high because I did a weekly shot of test/decca 3 days before the blood test. I wanted to see the peak values. I don't have any sides and blood pressure is fine (125/72).

I was on 125mg test e and 100mg decca.

 

[Freeboomboom]

Thats not very rare its actually kinda common with 300+ igf on a daily trt dose of 20mg test and 2iu hgh daily. Good response though

 

[s2kallday]

Serum igf levels are meaningless when evaluating HGH. They do not directly correlate to igf levels in tissue. Chase Irons was running 18iu serostim a day and his serum igf was in the 100's iirc lol.

 

[ShutUpAndPump]

It is normal bro, every single time i've run hgh it drops my creatinine levels that returns to baseline 2 weeks after i stop it. And yes with 2 iu it is normal your igf-1. Mine with 4.5 was 500 so i can relate to your experience

 

[Freeboomboom]

@Ghoul the obese kid on secretagogues who never run a cycle and done bloodwork.

Mr chatgpt.

Probably seen more bloodwork than he seen tits.

 

[ShutUpAndPump]

@bananafeet but why only 2 iu? Is it pharma or generic? Because from the results seems legit as pharma grade

 

[BigDadd7]

@Ghoul...
Probably seen more bloodwork than he seen tits.

That's a zinger. Im going to save that and use it (or a variant) on someone.

 

[bananafeet]

@bananafeet but why only 2 iu? Is it pharma or generic? Because from the results seems legit as pharma grade

It's generic Chinese stuff bro. 24iu vials. I keep it in an insulin cooler so it's always around 2 degrees Celcius. I think that helps it to stay potent.

I made my own bac water because I can't trust the stuff here.

 

[ShutUpAndPump]

It's generic Chinese stuff bro. 24iu vials. I keep it in an insulin cooler so it's always around 2 degrees Celcius. I think that helps it to stay potent.

I made my own bac water because I can't trust the stuff here.

Perfect, If I were you, I would still do other IGF 1 tests every now and then, because this time the vial was well dosed, but you have to be sure that the others are too.

 

[Ateam2023]

That's a zinger. Im going to save that and use it (or a variant) on someone.

that saying is " worthless as tits on a boar"