Defiant Pharma (US Domestic)

[RockyP]

The glucagon receptor agonism really kicks in at 4mg, I was just listening to something about Reta yesterday. Any dose of Reta is gonna hit the glucagon receptor but 4mg is where significant glucagon activity kicks in. Whether it kicks in harder at 8mg or not I don't know

That was my understanding. The significance of the 8 mg dosage I believe is where the linear dose-response relationship starts to level off. So up to and including 8 mg you get more and more benefit with each successive dosage in a linear fashion, but over 8 mg the incremental benefit wanes a bit, but still increases. The recent published trial went up to 12 mg which i can’t imagine taking. But I’ve seen more than a few users do that much and be fine with it.

Just to steer things back to something D related, since it is his thread... This new TNE in mig812 is really very nice. Super smooth with no pip. May bump it up to 100 mg next leg day. Only thing I can compare it to is injectable Anadrol. I find the TNE gives me better pumps without the crash / lethargy. And about the same strength increase. And saves the HDL / liver. Only thing is tho I never ran the Anadrol several days in a row. I do suspect that it would give a more pronounced effect if used regularly but I’m trying to avoid that.

One day I will stack the TNE with the Anadrol….

 

[Vikingo]

Received my first order from D last Friday, being as my underground privileges were restricted until now let me review. My experience with D was top notch! Great communication, fast shipping and his packaging is on point. None of the TNE 100mg/ml were crashed at all. Crystal clear not even a tiny crystal. His pills are the best pressed ugl I have ever had. The TNE is super smooth and works exactly as it should. Pinned 1ml each delt no pip whatsoever.

 

[Defiant Pharma]

That was my understanding. The significance of the 8 mg dosage I believe is where the linear dose-response relationship starts to level off. So up to and including 8 mg you get more and more benefit with each successive dosage in a linear fashion, but over 8 mg the incremental benefit wanes a bit, but still increases. The recent published trial went up to 12 mg which i can’t imagine taking. But I’ve seen more than a few users do that much and be fine with it.

Just to steer things back to something D related, since it is his thread... This new TNE in mig812 is really very nice. Super smooth with no pip. May bump it up to 100 mg next leg day. Only thing I can compare it to is injectable Anadrol. I find the TNE gives me better pumps without the crash / lethargy. And about the same strength increase. And saves the HDL / liver. Only thing is tho I never ran the Anadrol several days in a row. I do suspect that it would give a more pronounced effect if used regularly but I’m trying to avoid that.

One day I will stack the TNE with the Anadrol….

Received my first order from D last Friday, being as my underground privileges were restricted until now let me review. My experience with D was top notch! Great communication, fast shipping and his packaging is on point. None of the TNE 100mg/ml were crashed at all. Crystal clear not even a tiny crystal. His pills are the best pressed ugl I have ever had. The TNE is super smooth and works exactly as it should. Pinned 1ml each delt no pip whatsoever.

Thanks to both of you for the honest reviews fellas. As always, I greatly appreciate it and very happy y'all are loving the TNE.

It's definitely become a new favorite inject of mine. Especially with early morning workouts, it's a game changer.

 

[Inkniron87]

My TNE is supposed to arrive the same day as my nipro 30g 1/2". Man I cant wait. If this shit hits like you all say I hope you have plenty more @Defiant Pharma lol

 

[hcgfiend123456]

No no not back to back. This was two separate occasions. And honestly the funny thing is, I’m leaner and stronger now just using test, Reta, and gh than I ever was on those cycles back then. And I’ve only been back in the gym for roughly a year after going off on a three year liquor bender. Lost all my strength and weight that I gained over the years from drinking like that. Never again

Ya fuck alcohol man. Once in a while I drink a beer but most of the men in my family destroyed their lives with booze from the 80s - mid 2010's.

 

[hcgfiend123456]

I was on 8mg of Reta and ran 50mg/day of var for 5 weeks and my hdl went from 35 to 34, so there’s some variance in how it affects individuals. Only slightly uncommon things I added was pita and eze

Im about the same with var. Test does more to my lipids.

 

[RockyP]

Ya fuck alcohol man. Once in a while I drink a beer but most of the men in my family destroyed their lives with booze from the 80s - mid 2010's.

Haven’t had a drink in years and don’t plan on it ever again. Totally just doesn’t jive with this lifestyle. And I’d rather use Anadrol / winstrol if I want to give my liver a push.

 

[hcgfiend123456]

How much TNE are you using for preworkout? I’m gonna give it a try. From the sounds of it, this will be perfect for my early morning leg and back days

TNE sounds like a blast. No pun intended. Trying to lean out on reta before I use any. I aromatize too highly to feel comfortable running any.

 

[RockyP]

Im about the same with var. Test does more to my lipids.

I’m very jealous of you two. Var trashes my HDL but my LDL is quite low. Even still I have to use restraint. I would totally run it year round otherwise.

 

[RockyP]

TNE sounds like a blast. No pun intended. Trying to lean out on reta before I use any. I aromatize too highly to feel comfortable running any.

It’s in and out quickly. Depends on how you aromatize in general. I mentioned it a few pages ago but I had labs drawn when on HRT (which was an TNE cream 2x daily) and my DHT was very high and e2 was in range. So I was converting most of the test to DHT rather than E2. The TNE doesn’t give me any bloat or other noticeable signs of increased aromatization.

 

[Vikingo]

I haven’t noticed any aromatization from the TNE and I typically do 200mg on leg and back days 150mg all other training days. .

 

[hcgfiend123456]

It’s in and out quickly. Depends on how you aromatize in general. I mentioned it a few pages ago but I had labs drawn when on HRT (which was an TNE cream 2x daily) and my DHT was very high and e2 was in range. So I was converting most of the test to DHT rather than E2. The TNE doesn’t give me any bloat or other noticeable signs of increased aromatization.

Is the conversion to DHT a function of the ROA or because of how it breaks down so quickly?

 

[hcgfiend123456]

I haven’t noticed any aromatization from the TNE and I typically do 200mg on leg and back days 150mg all other training days. .

Is that on top of your normal dose of testosterone or is that in addition to?

 

[RockyP]

Is the conversion to DHT a function of the ROA or because of how it breaks down so quickly?

I think it’s just how I was processing fast acting test. I aromatize low-medium range on longer esters. On a gram of test E / C my e2 was 80

 

[hcgfiend123456]

I think it’s just how I was processing fast acting test. I aromatize low-medium range on longer esters. On a gram of test E / C my e2 was 80

Are you really low BF%?

 

[RockyP]

Are you really low BF%?

I’m about 10% at 225-227 at the moment

 

[Vikingo]

Is that on top of your normal dose of testosterone or is that in addition to?

On top of my normal dose. I’m currently running 1.2g test e per week and 150mg test P per day for the first 3 weeks of blast. I’m in week 2 of this run.

 

[hcgfiend123456]

@Photon idk why you always laugh at my posts but you are a troll.

 

[Infernalmango]

Im about the same with var. Test does more to my lipids.

It’s a small blessing not getting absolutely thrashed by orals. Lipids in general stay very solid. My biggest battle in this hobby is hematocrit and it’s an annoying cunt to deal with for sure.

 

[Photon]

@Photon idk why you always laugh at my posts but you are a troll.

I try my best my dear