Accutane permanent cure?

Hi everyone,

Just checking back in. So I did my maths again and realized I was a little off after my last post — currently just shy of 10000mg total dosage after counting through what was left in my Indian Pharma stash.

I am now running only 20mg everyday and will drop to 10mg everyday until the capsules are done, then begin with the 5mg a day for as long as I feel necessary, keeping the 40mg’s on standby just in case.

For those who are new and missed it, although I highly suggest reading through the thread, the TLDR is I took the high dose approach for right around 3 months to hit a little over 9000mg and dropped down due to starting a cycle.

Here are the bonuses:

— no dry skin anywhere — lips, face, elbows, ankles, hands has almost entirely dissipated. Lips still need lip balm, but less frequent.
— going into wk 6 of Test/Mast/NPP at 675/400/150 I would expect at least a few pimples… absolutely nothing at all is showing up (knock on wood)

Have some goodies coming in from India to further benefit the skin:
- Azelaic Acid 20% and Hydroquinone 4% (for issues with hyperpigmentation from old acne)
— Tretinoin .025% (for a myriad of reasons)

I will continue to report back and also inform members about the efficacy of the above topicals when I feel I have used them long enough)

Best wishes to you fellas just starting up! You got this!
 
I had to drop down from 160mg/day to 120mg due to joint pain in knees, elbows, and shoulders. Hoping to bump up to 140mg once the pain settles and finish out my high-dose run there.

Anyone see joint pain improvement from a similar decrease?
To be fair, 160mg is pretty brutal... What is your weight?
 
Have some goodies coming in from India to further benefit the skin:
- Azelaic Acid 20% and Hydroquinone 4% (for issues with hyperpigmentation from old acne)
— Tretinoin .025% (for a myriad of reasons)
I started tretinoin along side dapsone gel - and doxepine- and had decent results before I started the accutane run. Domestic cost for the daspone is stupid, and part of what started me looking harder at accutane. Indian pharma has it (usually at 5% instead of 7.5%) for much less though. It's essentially an antibacterial so may or may not be useful depending on your situation.
 
Just got my india order.

Using doxy/tetracycline currently to try to control acne a bit.

Hoping accutane will do better.
Im needing to go back thru and re-educate myself on this thread.

I ordered 5mg capsules because I dont swallow meds well, was hoping these would be the smallest size...

Thinking about doing 5 or 10mg per day to minimize sides (which ive heard are often overblown.

But that seems like a truly microscopic dose compared to the above.

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Just got my india order.

Using doxy/tetracycline currently to try to control acne a bit.

Hoping accutane will do better.
Im needing to go back thru and re-educate myself on this thread.

I ordered 5mg capsules because I dont swallow meds well, was hoping these would be the smallest size...

Thinking about doing 5 or 10mg per day to minimize sides (which ive heard are often overblown.

But that seems like a truly microscopic dose compared to the above.

View attachment 381661
You really screwed your self on this one. They're all about the same size, so now you'll need to take more pills at once to reach your desired dosage.

5mg probably isn't going to do much to help with moderate or worse acne.

I just started my treatment. I did 5mg a day the first week, almost no noticeable effects other than slight chapped lips.

Now I'm on my fourth day of 10mg and got my first nose bleed and the chapped lips are much more noticeable.

Hopefully 20mg daily gets me to my sweet spot. I only break out badly when I blast so I'm hoping I can ride 20mg until my cruise.

Best of luck to you.
 
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Time to place another india order, I guess.

But hey, maybe this will actually force me to learn how to swallow pills better.
Definitely order a decent amount of 40’s, 20’s, and 10’s so you can play around with your dosing a fair bit. The variation in dosages comes in pretty handy.

At least with 5mgs you can get a start and assess your tolerance. I wouldn’t expect anything crazy from 5mg or 10mg, but it’s not a bad idea to start low. The standards for longer term low dosing seem to keep most people around 20-40mg per day.

Also, give some time for the doxycycline to leave your body. Doxy and Accutane can have a rare drug interaction called Pseudotumor cerebri that you definitely want to avoid.
 
Definitely order a decent amount of 40’s, 20’s, and 10’s so you can play around with your dosing a fair bit. The variation in dosages comes in pretty handy.

At least with 5mgs you can get a start and assess your tolerance. I wouldn’t expect anything crazy from 5mg or 10mg, but it’s not a bad idea to start low. The standards for longer term low dosing seem to keep most people around 20-40mg per day.

Also, give some time for the doxycycline to leave your body. Doxy and Accutane can have a rare drug interaction called Pseudotumor cerebri that you definitely want to avoid.
Super helpful thank you.
I like this approach

Question because Im a little bitch: are the 20s and 40s generally a larger size capsule?
 
Super helpful thank you.
I like this approach

Question because Im a little bitch: are the 20s and 40s generally a larger size capsule?
No problem! So many different approaches to take — I did almost 3 months of high dose (120-140mg) and then hopped on cycle and I’m down to taking 10mg and 20mg on alternating days.

All capsules are the same size, only difference is the color coding!
 
Just got my india order.

Using doxy/tetracycline currently to try to control acne a bit.

Hoping accutane will do better.
Im needing to go back thru and re-educate myself on this thread.

I ordered 5mg capsules because I dont swallow meds well, was hoping these would be the smallest size...

Thinking about doing 5 or 10mg per day to minimize sides (which ive heard are often overblown.

But that seems like a truly microscopic dose compared to the above.

View attachment 381661
If you want full, permanent clearance of chest and back acne, you're going to need up to 220mg/kg of body weight. If we assume you weigh 220 pounds (100kg) that is 22,000mg total. At 5mg per day that's 12 years (and you probably won't reach the saturation you need at that rate anyway). Read the beginning of this thread for Ghoul's journey. (RIP Ghoul)
 
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