Accutane permanent cure?

[AllbrandNew]

I powered through 120 over 10 days of dry everything. I'm finally stable, gonna hang here I think and ride it out. Did you split your dose? I take 80 in the AM and 40 PM.

I split everything over 40mg up AM/PM, if nothing else that to try to minimize the sides. At 120 it was a little easier to do the 80mg PM, seemed like everything was a bit less dry during the day than the reverse.

 

[white-boyka]

do you build a ”tolerance” so to speak to a given dose. not in the sense that’s it is ineffective, but in the sense of sides like dryness etc decreasing as you spend time as a certain dosage.

 

[synthetic_juggernaut]

do you build a ”tolerance” so to speak to a given dose. not in the sense that’s it is ineffective, but in the sense of sides like dryness etc decreasing as you spend time as a certain dosage.

Yeah, for me the sides (nosebleeds, chapped lips) were terrible for the first few days at a new dose level but got better soon after. I was very aggressive with dose increases: 4 days at 40mg AM; 10 days at 80 mg (40/40 split); 5 days so far at 120 mg (40/80 split). Cortibalm lip cream from Amazon has been a lifesaver too.

 

[simpygliz]

120mg is nuclear... Why don't you go on lower

Yeah, for me the sides (nosebleeds, chapped lips) were terrible for the first few days at a new dose level but got better soon after. I was very aggressive with dose increases: 4 days at 40mg AM; 10 days at 80 mg (40/40 split); 5 days so far at 120 mg (40/80 split). Cortibalm lip cream from Amazon has been a lifesaver too.

120mg is nuclear... Why don't you go on lower dosage?

 

[synthetic_juggernaut]

120mg is nuclear... Why don't you go on lower

120mg is nuclear... Why don't you go on lower dosage?

I want to get done before summer and need to get through 400 40mg pills to hit the top end of the cumulative dose for my weight. I'm doing one strong course to hopefully permanently stop getting breakouts when starting and ending blasts going forward.

 

[level3]

I powered through 120 over 10 days of dry everything. I'm finally stable, gonna hang here I think and ride it out. Did you split your dose? I take 80 in the AM and 40 PM.

Yeah I split it, 40 AM 60 PM, since I take it with lunch and dinner which are only 6-8 hours apart, so I take the larger dose with dinner.

 

[adrenalytic]

I split everything over 40mg up AM/PM, if nothing else that to try to minimize the sides. At 120 it was a little easier to do the 80mg PM, seemed like everything was a bit less dry during the day than the reverse.

Thanks for the tip. Trying this for a few days to see if it helps.

 

[explodingHeart]

Seriously though, what happened to @Ghoul

 

[ekim]

Yeah. Feeling his absence in multiple threads. That's for sure.

Anyway, I'm ending week 4 of his high-dose protocol. Bumped up to 140 mg today. I'm now fully armed with face lotion, body lotion, Aquaphor, Vaseline (inside nose), and eye drops.

I'm still hoping someone will chime in and explain the high DAILY dose benefits that I can't seem to find or remember (thought it was in this thread).

 

[powerdiesel]

I'm still hoping someone will chime in and explain the high DAILY dose benefits that I can't seem to find or remember (thought it was in this thread).

My understanding is the only benefit of the higher daily dose is it gets you to the total cumulative dose earlier. The area under the curve will be the same, just a tradeoff between sides and duration. Only caveat to this would be tiny daily doses that would make your duration excessively long (years instead of months) that could negatively impact recurrence risk.