Filtering injectables too many times makes less potent?

[PS LABS FOUNDER]

HEY DOES ANYONE KNOW IF FILTERING {WITH SYRINGE FILTER .45} TOO MANY TIMES {3X OR MORE} IS BAD AND WILL FILTER OUT SOME OF THE STEROID MAKING THE OIL LESS POTENT?

I JUST HAD A MASSIVE AMOUNT OF TEST C 300 THAT I FILTERED 3X TO GET IT REALLY CLEAN AND SMOOTH AND WITH 2% BA AND 12% BB / BUT ITS SO SMOOTH WHEN I INJECT IT IM WONDERING IF I FILTERED TOO MUCH AND GOT SOME OF THE STEROID OUT OF THE OIL??

DOES ANYONE KNOW IF FILTERING THE GEAR TOO MUCH WILL MAKE IT WEAKER OR JUST BETTER CLEANED?

THANKS GUYS

 

[ElliotV]

I don't think filtering something multiple times with the same pore size filter is going to make is any "cleaner."

Depending on what type of filter it is (do not say Whatman) some could possibly bind to the medium.

El

 

[Stretch]

I don't think filtering something multiple times with the same pore size filter is going to make is any "cleaner."

Depending on what type of filter it is (do not say Whatman) some could possibly bind to the medium.

El

You dont like whatman?

 

[ElliotV]

You dont like whatman?

Whatman is a brand, not a type lol. There are many types of Whatman filters. But no, I prefer Millipore

Type e.g. nylon, PVDF, PTFE, mix esters....

 

[Mr. Joe]

No, filtering it multiple times will only lead to loss of volume. And elliot is right, filtering multiple times is pointless unless you think something has happened to it since you last filtered it.

 

[PS LABS FOUNDER]

?? You guys are saying filtering something 1 time and filtering it 10 times would not make it any cleaner? Sorry i have to disagree with that - or else what would be the point of ever changing a filter?
Why not use the same filter for 20 vials then if it doesnt matter ??

I think if you had say a bunch of dust or something in ur oil then filtering it 1 time com paired to 5 times there would be a difference

i just filtered it 3x to see if it made it smoother or cleaner cause 300mg per ml is pretty high concentration

 

[Mr. Joe]

Think about it this way, a .45 micron filter has a series of pores throughout the material the largest of which is .45 microns in diameter. When you run something through that filter EVERYTHING that passes through has a diameter less than .45 microns. So running that same solution through the same size filter will yield no further benefit.

This is true unless you are passing more material through the filter than it is rated for causing it to breakdown. In which case you should buy a larger filter or break up the volume to be filtered into more manageable amounts.

Below is a nice little pdf from Corning about choosing the right filter for your application.

http://catalog2.corning.com/Lifesciences/media/pdf/t_filterselectionguide.pdf

 

[Mr. Joe]

Whatman is a brand, not a type lol. There are many types of Whatman filters. But no, I prefer Millipore

Type e.g. nylon, PVDF, PTFE, mix esters....

May I ask how old you are? Some friends and I have a theory that you can roughly date a persons birth to before or after 1990 by the way they type smiley faces.

I know that's random but im curious so born before or after 1990?

 

[Dr JIM]

Sure PLF that seems intuitive BUT the primary factor which determines filtering capacity is the the size of the filtering pores, the compound/s being filtered and the degree of contamination.

Obviously the entire point of filtering any AAS is to diminish contamination, (especially bacteria, particulate matter and some viruses) while maintaining the relative concentration of the product. The oils and AAS used are VERY small compared to the retained contaminants.

Consequently unless your meeting considerable resistance to flow, which is indicative of contaminant obstruction, "repetitive filtering" (more than 3 times) is of limited benefit, IMO!

 

[PS LABS FOUNDER]

well you guys have points BUT WHY DOES IT GET EASIER EVERY TIME I FILTER IT TO GO THROUGH THE FILTER? LIKE THERE IS A DIFFERENCE FROM THE 1ST FILTER TO THE 2ND OBVIOUSLY ...B UT THEN IT GETS EVEN EASIER THE 3RD FILTER? THIS MEANS IN MY MIND THAT SOME OF THE THINGS THAT DIDNT GET CAUGHT IN THE 1ST FILTER GOT CAUGHT IN THE 2ND FILTER

BUT IT IS NOTICEABLE SMOOTHER AFTER 3 FILTERS ..BUT LIKE JIM SAID IM SURE THE CHEMICALS I WANT {HORMONE POWDERS} ARE MUCH SMALLER WHEN DISSOLVED THEN .45 FILTER SO I SHOULD BE FINE

- I THINK I WILL FITLER ALL MY STUFF 3 TIMES NOW THOUGH BECAUSE IT DID GET EASIER EACH TIME THROUGH THE FILTER

 

[Dr JIM]

I think your assumption is correct! Why because most of the filters pores when essentially pressure is exerted upon them. This distortion catches larger material yet allows smaller contaminants to pass.

Each pass should catch smaller and smaller particulate material, with the result being easier passage of the AAS/OIL combo, because there is LESS JUNK to clog the filter.

Remember exert slow and steady pressure with each pass since more unwanted material is snagged using that technique.

Nonetheless no difference (in the pressure needed) should be noted after THREE passes, unless either the AAS powder or oil are overly contaminated, IMO!

jim

 

[Dr JIM]

To clarify PLF

Why, because the majority, if not all paper filters, undergo "porous distortion" when heavy pressure is required to push more viscous solvents (like oils) thru them. This distortion actually makes the pores larger allowing smaller materials to pass through ..... the smaller and smaller particles should be caught with each successive pass, such that after the third pass only the AAS/OIL base remain.

GTG mate?


jim

 

[ElliotV]

May I ask how old you are? Some friends and I have a theory that you can roughly date a persons birth to before or after 1990 by the way they type smiley faces.

I know that's random but im curious so born before or after 1990?

What do you think?

 

[Stretch]

Whatman is a brand, not a type lol. There are many types of Whatman filters. But no, I prefer Millipore

Type e.g. nylon, PVDF, PTFE, mix esters....

Thanks. I knew that. You seemed to have a problem with the brand I happen to use, so I was curious if there was a concrete reason to switch.

 

[ElliotV]

Well besides coming in fun colors, Millipore has a nice little device that can turn a syringe filter into a vacuum with a hand pump. So it just makes it a little easier. I believe certain ones also have a higher volume rating.

 

[Stretch]

Well besides coming in fun colors, Millipore has a nice little device that can turn a syringe filter into a vacuum with a hand pump. So it just makes it a little easier. I believe certain ones also have a higher volume rating.

Got it.

I use the whatman "zap cap" bottle-top filters personally. With a vacuum pump.

 

[Mr. Joe]

What do you think?

Your style of smiley "" suggests after. Cause everyone born before 1990 should know that "" is correct (even the internet recognizes : ) as correct). But judging by your photo I can't tell. Maybe you just hang around too many youngins.

 

[Mr. Joe]

well you guys have points BUT WHY DOES IT GET EASIER EVERY TIME I FILTER IT TO GO THROUGH THE FILTER? LIKE THERE IS A DIFFERENCE FROM THE 1ST FILTER TO THE 2ND OBVIOUSLY ...B UT THEN IT GETS EVEN EASIER THE 3RD FILTER? THIS MEANS IN MY MIND THAT SOME OF THE THINGS THAT DIDNT GET CAUGHT IN THE 1ST FILTER GOT CAUGHT IN THE 2ND FILTER

BUT IT IS NOTICEABLE SMOOTHER AFTER 3 FILTERS ..BUT LIKE JIM SAID IM SURE THE CHEMICALS I WANT {HORMONE POWDERS} ARE MUCH SMALLER WHEN DISSOLVED THEN .45 FILTER SO I SHOULD BE FINE

- I THINK I WILL FITLER ALL MY STUFF 3 TIMES NOW THOUGH BECAUSE IT DID GET EASIER EACH TIME THROUGH THE FILTER

Im curious as to what type of filter you are using also. Im not experienced with filtering hydrocarbons, but it may be that your filter is binding the oil preferentially. Another separate concern is whether or not the filter is resistant to the alcohol you're running through.

Has anyone tried different filtering materials (PES, nylon, CA, CN, RC, etc) with AAS and noted the differences.

 

[PS LABS FOUNDER]

yes exactly - i think 3x filter is best and needs no more then 3 / but 3 does make a difference i can tell

i think your assumption is correct! Why because most of the filters pores when essentially pressure is exerted upon them. This distortion catches larger material yet allows smaller contaminants to pass.

Each pass should catch smaller and smaller particulate material, with the result being easier passage of the aas/oil combo, because there is less junk to clog the filter.

Remember exert slow and steady pressure with each pass since more unwanted material is snagged using that technique.

Nonetheless no difference (in the pressure needed) should be noted after three passes, unless either the aas powder or oil are overly contaminated, imo!

Jim

 

[PS LABS FOUNDER]

im curious as to what type of filter you are using also. Im not experienced with filtering hydrocarbons, but it may be that your filter is binding the oil preferentially. Another separate concern is whether or not the filter is resistant to the alcohol you're running through.

Has anyone tried different filtering materials (pes, nylon, ca, cn, rc, etc) with aas and noted the differences.

sorry i cant really tell you cause i dont know as there is no brand name on them just the measurements and stuff
- its .45um and celluloseacetate 25mm diameter
i used 2% ba and 12% bb