Nandrolone with Dutasteride?

[Var4theHuzz]

Effects vs without and if it is a good idea to use.
I have RU for hair and Accutane for acne.
This would in theory prevent conversion into DHN and preserve nandrolones anabolicity by preventing the convesrion
Has anyone used this?
Thank you

 

[BP_6]

Effects vs without and if it is a good idea to use.
I have RU for hair and Accutane for acne.
This would in theory prevent conversion into DHN and preserve nandrolones anabolicity by preventing the convesrion
Has anyone used this?
Thank you

Dhydronandrolone is actually a rather weak androgen. That is one thing that is unique about it. Normally the 5 alpha reductase enzyme makes something more androgenic, but in the case of nandrolone it is the opposite.

DHN is not likely going to be an issue for hair loss. At least compared to everything else.

 

[Var4theHuzz]

Dhydronandrolone is actually a rather weak androgen. That is one thing that is unique about it. Normally the 5 alpha reductase enzyme makes something more androgenic, but in the case of nandrolone it is the opposite.

DHN is not likely going to be an issue for hair loss. At least compared to everything else.

I read that it is also a lot less anabolic compared to Nandrolone so would inhibiting its conversion in a stack therefore increase the anabolicity of NPP/Deca?
I read that an estimated 20-40% is converted so would this not create a significant boost to the cycle?

 

[null88]

Using a 5-ARI with nandrolone would in theory increase its androgenicity probably keep the same level of anabolism, I don't think there is any human clinical data measuring this though. 5-AR is expressed inside the cell of certain tissues (skin, prostate, brain,..etc) so when nandrolone is converted to DHN, it should reduce AR signaling in those tissues. Muscle tissue has very little 5-AR, so the muscle building effects of nandrolone shouldn't really be affected if taking a 5-ARI. Of course given enough AAS, you will fully saturate the 5-AR.

 

[Sicsemptyran]

I read that it is also a lot less anabolic compared to Nandrolone so would inhibiting its conversion in a stack therefore increase the anabolicity of NPP/Deca?
I read that an estimated 20-40% is converted so would this not create a significant boost to the cycle?

As @null369 mentioned, you mostly just get more androgenic effects, not really an anabolic boost. The nandrolone just won't convert to DHN in the tissues with high 5AR (NOT MUSCLE), so it will be a stronger androgen in things like the skin/prostate/brain as he calls out.

You may theoretically get more nandrolone floating around to be used by the muscle because it's not being converted into DHN in those tissues, but you're talking about on the margins. Mostly just higher androgenicity.

For what it's worth, I ran NPP for a bit with dutasteride just because I take dutasteride to begin with and was pretty underwhelmed in general.