Yeah I've seen the whole "teaspoon in a bathtub" explanation before and pun intended, it doesn't seem to hold water. Let's look at the numbers.Reason why not to microdoseView attachment 362164
Six day halflife. Let's take a 1mg dose as an example. That means I take 1mg Monday, .5 mg remains in my system the following Sunday. So each day represents approximately 1/12th of that 1mg diminished. After the halflife is reached it takes 5 halflives for the original dose to leave your system.
So if you want 1mg of Reta to remain in your system as your effective dose, you take .5 mg Monday, Wednesday and Friday. This builds the concentration of Reta in your system week after week, since each microdose keeps your serum ahead of the rate of depreciation. The bathtub slowly fills.
This allows for each person to reach their own personalized minimum effective dose, and they are either going to hit slight side effects (i.e. ease off on the dose) or hunger signaling (i.e. increase *one* of the microdoses). Either way the bathtub keeps filling, over a longer period of time, and many people may never need to reach the supposed effective thresholds of 8+ mg that the trials suggest have the greatest impact. Less drug burden. Personalized effectiveness. Less money spent.
Or you can just crank that shit once a week because Eli Lilly said so...

