How HCG affect my testosterone level

[ganciodestro]

Hi guys, as the title says, I wanted to show you what I noticed in my blood tests. Three weeks ago, I did blood work while using only 205 mg of testosterone cypionate subq, divided into three shots per week, and I wasn’t taking HCG. My total testosterone was 1225, and my estradiol was 41.

Afte e those tests, I lowered my testosterone dose to 172.5 mg, still subq and divided into three shots, and added 250 IU of HCG, also three times a week. I repeated the blood work three weeks later and noticed that my total testosterone rose to 1590 and my E2 to 61. I didn’t expect such a marked increase in total testosterone (I had these total testosterone numbers with 225 mg per week, plus 50 +mg then now, and without HCG).
I don’t have any symptoms of high E2 except for occasional slight mood swings. Do you think I should use an AI?

HCG gives me a sense of libido that testosterone alone doesn’t, and it keeps my testicles normal, so I don’t want to stop it.

I also wanted to share that in just three weeks of ezetimibe at 5 mg per day, I lowered my LDL from 97 to 65 and my HDL increased from 35 to 39 (this could also be partially related to the increase in E2).
Never tested apob before , but now is 0.49
Thanks @Ghoul
Still not using pravastatine

 

[ganciodestro]

In there three weeks Also My hct drop from 53 to 51.7
(With no drug my baseline is 49)

Testosterone total 1225 to 1590

E2 41 to 61

Always used same brand testosterone and hcg (driada medical)

 

[ganciodestro]

Up

 

[k710]

In there three weeks Also My hct drop from 53 to 51.7
(With no drug my baseline is 49)

Testosterone total 1225 to 1590

E2 41 to 61

Always used same brand testosterone and hcg (driada medical)

Hey there,

Im trying to understand the effects of hcg on my levels as well. I feel like I get a big spike in e2 for a day or two after my dose. Was dfoing every other day administration and switched to twice a week to see if I felt peaks and valleys between doses. Definitely can feel it. I hadnt checked my total T without and with hcg since I started it along with my test.

At 200mg test-c/week my total T was around 1400 and my estrodial was at 22. Bumped up to 300mg test-c/week and my E2 jumped from 22 to 60. Introduced low dose of Primo (60mg/week) and ran labs about 5 weeks later. E2 back down to 34, almost a 50% cut.

You want to avoid using AI's if you can. Shits toxic and only cuts your e2 without providing benefits to your growth. Have to be careful to not crash your estrogen as well or you'll be misereable for a bit.

If you can use a DHT derivative as a second compound then you can get the same estrogen management with the added benifits of more gains. If your gonna use something toxic, might as well having it contribute to your growth goals

 

[ganciodestro]

Hey there,

Im trying to understand the effects of hcg on my levels as well. I feel like I get a big spike in e2 for a day or two after my dose. Was dfoing every other day administration and switched to twice a week to see if I felt peaks and valleys between doses. Definitely can feel it. I hadnt checked my total T without and with hcg since I started it along with my test.

At 200mg test-c/week my total T was around 1400 and my estrodial was at 22. Bumped up to 300mg test-c/week and my E2 jumped from 22 to 60. Introduced low dose of Primo (60mg/week) and ran labs about 5 weeks later. E2 back down to 34, almost a 50% cut.

You want to avoid using AI's if you can. Shits toxic and only cuts your e2 without providing benefits to your growth. Have to be careful to not crash your estrogen as well or you'll be misereable for a bit.

If you can use a DHT derivative as a second compound then you can get the same estrogen management with the added benifits of more gains. If your gonna use something toxic, might as well having it contribute to your growth goals

Hi! I’m glad to hear that you were able to keep your E2 under control with such a low dose — I’ll probably go for a similar setup if needed. You were keeping roughly a slightly higher than 4:1 ratio (test to primo).
I’m a bit hesitant to add other AAS because I struggle a lot with high hematocrit, even though I drink plenty of water, do cardio, etc. (I also take grapefruit extract).


What really surprises me the most is that I had a total testosterone of 1225 with about 205 mg of testosterone cypionate, but after lowering the dose to 172.5 and adding Gonasi (hCG), my total testosterone went up to 1550 — roughly what I’d get with 225 mg of testosterone cypionate — but without the effects of a higher dose (less strength, less muscle tone, and less drive). My blood value is higher, but I feel weaker… really crazy stuff.

 

[k710]

Hi! I’m glad to hear that you were able to keep your E2 under control with such a low dose — I’ll probably go for a similar setup if needed. You were keeping roughly a slightly higher than 4:1 ratio (test to primo).
I’m a bit hesitant to add other AAS because I struggle a lot with high hematocrit, even though I drink plenty of water, do cardio, etc. (I also take grapefruit extract).


What really surprises me the most is that I had a total testosterone of 1225 with about 205 mg of testosterone cypionate, but after lowering the dose to 172.5 and adding Gonasi (hCG), my total testosterone went up to 1550 — roughly what I’d get with 225 mg of testosterone cypionate — but without the effects of a higher dose (less strength, less muscle tone, and less drive). My blood value is higher, but I feel weaker… really crazy stuff.

Supplementing 500mg of Curcumin and aggresive omegas (3000-4000mg) daily helped me with hematocrit and bp control if you want to take a look at those. Theres other things marketed at high hematocrit specifically but I havent really seen any proof of them actually working. Imo its a marketing thing to charge more money.

And yea its wild how differently the body can feel. I too hit a point where I was feeling weaker while on the same dose, but I think that was more that I found my e2 threshold at 60ish ng/dl and was holding more water, mood wasnt as high, and I started growing one titty. Theres tons of variables that could affect you feeling weaker (nutrition, poor sleep ect) but a large aspect seems to be psychological. The mind is a powerful thing. Best you can do is pay attention, and get data to better learn how you respond to the different compounds.

Keep this updated with your finding on hcg and testosterone levels.
Im assuming you pulled your labs at trough both times. I take hcg 2x/week at 500mg each. So if I dosed Monday, next would be thursday. Ill run labs thursday and take my hcg dose after blood drawn.

 

[ganciodestro]

Supplementing 500mg of Curcumin and aggresive omegas (3000-4000mg) daily helped me with hematocrit and bp control if you want to take a look at those. Theres other things marketed at high hematocrit specifically but I havent really seen any proof of them actually working. Imo its a marketing thing to charge more money.

And yea its wild how differently the body can feel. I too hit a point where I was feeling weaker while on the same dose, but I think that was more that I found my e2 threshold at 60ish ng/dl and was holding more water, mood wasnt as high, and I started growing one titty. Theres tons of variables that could affect you feeling weaker (nutrition, poor sleep ect) but a large aspect seems to be psychological. The mind is a powerful thing. Best you can do is pay attention, and get data to better learn how you respond to the different compounds.

Keep this updated with your finding on hcg and testosterone levels.
Im assuming you pulled your labs at trough both times. I take hcg 2x/week at 500mg each. So if I dosed Monday, next would be thursday. Ill run labs thursday and take my hcg dose after blood drawn.

I didn’t know curcumin had a beneficial effect on hematocrit, I’ll definitely consider taking it!
How much does it lower your hct?

I already take omega-3!

My blood pressure is always perfect, and even my resting heart rate — fortunately or unfortunately — I’ve never had side effects from high hematocrit.

As for the feeling, it’s true that part of it is psychological. But even in terms of muscle and strength, I notice a slight drop in performance, even though my lab results show that testosterone actually went up despite lowering the dose.

It’s definitely due to hCG, but it doesn’t provide the same anabolic effect as 225 mg of testosterone, even though total testosterone levels are as high as they would be on that dose.

I take 250 IU of hcg after each injection of testosterone cypionate, which I do three times a week subcutaneously.

 

[k710]

I didn’t know curcumin had a beneficial effect on hematocrit, I’ll definitely consider taking it!
How much does it lower your hct?

I already take omega-3!

My blood pressure is always perfect, and even my resting heart rate — fortunately or unfortunately — I’ve never had side effects from high hematocrit.

As for the feeling, it’s true that part of it is psychological. But even in terms of muscle and strength, I notice a slight drop in performance, even though my lab results show that testosterone actually went up despite lowering the dose.

It’s definitely due to hCG, but it doesn’t provide the same anabolic effect as 225 mg of testosterone, even though total testosterone levels are as high as they would be on that dose.

I take 250 IU of hcg after each injection of testosterone cypionate, which I do three times a week subcutaneously.

Well actually you are right.. theres contradicting data on curcumin and elevating or lowering red blood cell production depending on other health conditions one might have. It honestly got added to my stack by my coach b.c I thought I was having bp issues.. (was using the wrong size cuff, only slightly elevated) She added omegas and curcumin together and said that it might help blood viscosity and hopefully make me feel better. BP has been perfect since. Curcumin also helps fight inflamation which my broken body needs assistance with.

Looking back over some clinical studies, for hematocrit alone its prob not the best option. Sorry about that. Idk why I had it pinned to hematocrit in my head instead of inflamation.

Its pretty common that people report "hcg only increases your numbers on paper" due to the elevated levels not having the same affect as exogenous testosterone. Basically, what you are describing.. drop in performance, not feeling as good, ect.

I guess you can try stopping your hcg for a little before your next labs and draw again to get a more accurate reading of your test and estradiol levels at with your 172.5mg dose.

As far as E2 goes, my rule of thumb is if its at 50+ and symptomatic take action and get back under 40. If not symptomic, just monitor your symptoms and levels. Without using another compound, you would likely have to adjust your hcg dosing/schedule to see if e2 comes down or have to use an AI like anastrozole.

I also dont want to stop my hcg, but im pretty sure its the culprit behind my nip sensitivity. This is when I added primo and e2 went down almost 50% on a standard test. Hoping this will keep e2 under control and stop the gyno so I can keep my hcg as is. If not ill just lower my hcg dosage and go back to 3x/week administration. Was told I could try gonadorelin instead of hcg, but that it wouldnt really be the same.

Hopefully someone whos already gone through this will chime in, because im still trying to figure it out like you

 

[ganciodestro]

Well actually you are right.. theres contradicting data on curcumin and elevating or lowering red blood cell production depending on other health conditions one might have. It honestly got added to my stack by my coach b.c I thought I was having bp issues.. (was using the wrong size cuff, only slightly elevated) She added omegas and curcumin together and said that it might help blood viscosity and hopefully make me feel better. BP has been perfect since. Curcumin also helps fight inflamation which my broken body needs assistance with.

Looking back over some clinical studies, for hematocrit alone its prob not the best option. Sorry about that. Idk why I had it pinned to hematocrit in my head instead of inflamation.

Its pretty common that people report "hcg only increases your numbers on paper" due to the elevated levels not having the same affect as exogenous testosterone. Basically, what you are describing.. drop in performance, not feeling as good, ect.

I guess you can try stopping your hcg for a little before your next labs and draw again to get a more accurate reading of your test and estradiol levels at with your 172.5mg dose.

As far as E2 goes, my rule of thumb is if its at 50+ and symptomatic take action and get back under 40. If not symptomic, just monitor your symptoms and levels. Without using another compound, you would likely have to adjust your hcg dosing/schedule to see if e2 comes down or have to use an AI like anastrozole.

I also dont want to stop my hcg, but im pretty sure its the culprit behind my nip sensitivity. This is when I added primo and e2 went down almost 50% on a standard test. Hoping this will keep e2 under control and stop the gyno so I can keep my hcg as is. If not ill just lower my hcg dosage and go back to 3x/week administration. Was told I could try gonadorelin instead of hcg, but that it wouldnt really be the same.

Hopefully someone whos already gone through this will chime in, because im still trying to figure it out like you

I was actually convinced that hCG only increased E2 and not total testosterone levels, if I had known that earlier, I would’ve waited a bit longer before starting hCG… I really missed it though, because it gives you that boost in libido, erections, and performance that testosterone alone just doesn’t provide! At least for me…

Anyway, yes, I can confirm that hcg makes the nipples sensitive, it does the same to me, even though I’m basically asymptomatic when it comes to high E2 (I only feel it psychologically, with mood swings, some irritability, anxiety and sometimes a bit of aparty).

As for hematocrit, I’ve heard that methylene blue and nattokinase work well for that, have you ever heard of those?