MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
Ok that's helpful. Is this related to why people have increased RHR on Reta?
Ghoul
Member
No. That's because when GLP-1 receptors on the vagus nerve are agonized, it partially blocks the feedback signals that normally slow heart rate down. Usually the system adjusts to this over time so for most using the pharma protocols (stable doses, once a week, for long periods of time) it's a temporary problem.
You think weekly dosing is best? Seems like you get a high peak and then it wears off towards the end of the week.
Photon
Member
Do you think that following what was done in pharmaceutical trials that was done over years and proven to be both safe and effective over a large sample size, monitored by people more educated and smarter than me, is best?
Yes, I do think so and that's what I'm doing, abit higher dose then what was used but still.
(I also don't want to pin more than once lol)
Sure but pharmaceutical companies also have to consider what a common lazy patient will actually do. ie pin multiple times a week less likely to be compliant.
Liter O' Test
Member
thinking "more stable is better" is dumb bodybuilder thinking of applying hormone logic to everything
also, if you are less hungry right after a shot and more hungry near the end of the week, that can help you cycle carbs or have refeeds, keeping your metabolism up.
but who knows seems like we have a huge influx of 500lb people who dont lift in here
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Biglittlejoe
New Member
I see a lot of people on Reddit stacking tirz and reta.
Reta is so strong in the GIP department already, I don’t see why anyone would do that.
Photon
Member
17325matsg
New Member
Im swapping from sema to triz. Im currently taking 2.5mg of sema every week should i start off the tirzepatide on the lowest does of 2.5mg or can i start higher?
Ghoul
Member
Higher. You're at max Sema per the pharma protocol. Tirz at 7.5mg is typically the starting point when moving over. You may not notice an increase in desired effects until you reach 10mg.
I usually feel it the next day or two. Probably appetite will be affected tomorrow. Be patient don't take more you'll regret it.
Liter O' Test
Member
Has anyone came off tirz/sema and had a large appetite increase and regained? Thats how it works right?
I ask because I gave some to a buddy and hes been a dick lately so hoping he blows back up after he goes through his vials.
I ask because I gave some to a buddy and hes been a dick lately so hoping he blows back up after he goes through his vials.
Ghoul
Member
Sema rebound 2-4 weeks after stopping is a motherfucker!
3 gallon tub of ice cream in the Walmart parking lot at 1am if he's not careful kind of sugar cravings type of insanity lol.
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Hi all. I've been on glps for a while, but they don't seem to be doing much for me.
Currently on 20mg tirz, and I've been on it for at least a year, plus another year prior on Sema.
I initially lost about 10kg, but basically just stalled after.
Bought from QSC in the past, as well as SRY this time.
I get it that not every person responds the same, as well as upping the physical activity will help (just like with any attempt of losing weight)
Is there anything else i can try? Am i doing something wrong?
Currently on 20mg tirz, and I've been on it for at least a year, plus another year prior on Sema.
I initially lost about 10kg, but basically just stalled after.
Bought from QSC in the past, as well as SRY this time.
I get it that not every person responds the same, as well as upping the physical activity will help (just like with any attempt of losing weight)
Is there anything else i can try? Am i doing something wrong?
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