Thanks for sharing. Got a plot I will share. Let me find it.
MESO-Rx
Anabolic Steroids
How did the myth start that Primobolan was an AI?
- Thread starter eryximachus
- Start date
Switch from Arimidex to Aromasin
Rectangular hyperbola. More background on the MM kinetics math: https://febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.16124
forums.t-nation.com
From paper's methods section:
We employed two models to explore the relationship between testosterone and its metabolites. First, we used an empirical power law to assess the relationship of posttreatment circulating testosterone levels to E2 levels. We used exploratory plots stratified by age group, with scatterplot smoothing using generalized...
The Effects of Injected Testosterone Dose and Age on the Conversion of Testosterone to Estradiol and Dihydrotestosterone in Young and Older Men - PMC
Background: During testosterone (T) therapy, T is partly converted to 17β-estradiol (E2) and 5α-dihydrotestosterone (DHT). Effects of age, testosterone dose, and body composition on total and free E2 and DHT levels are unknown. Objective: We ...
pmc.ncbi.nlm.nih.gov
What folks are trying to share. Your E2 and fE2 are quite low given your fT based on clinical trial data.
We would still need control expt for you to confirm effect of Primo on you.
Edit: notice some things never change around here. Pardon dickheads appearance in the link.
malomkarom
Member
This hasn't been the topic for a single second since this conversation started. Not for a single second.
why the fuck am I here again? fml
Increase your calm. We are almost there.
That's what it says in the labs I posted. Surely, you can understand why I would be at least somewhat confused.
malomkarom
Member
insert angry-laugh-wow-hearteyes emoji
I don't think I've been this pissed in years other than the 200mcg Trumpers company incident. I'm genuinely here to try and improve shit and help people do this shit with less risks, then there's these guys... I have a hard time believing he doesn't realize all the symptoms, his bloodwork is shit enough to the point he shouldn't really get an erection without help, you'd think that's a tell for a man. Let's not talk about the rest of it, just the sex hormones is enough.
Some people are destined to die in their 30s-40s and live in joint pain, imflammation, ED and either paranoia or psychosis and there's nothing I can do about it. Time to accept I guess. The actually fun part was over like 15 pages ago.
I honestly admire your patience man, hats off.
I'm starting to question whether you even speak english at this point.
my man is arguing about how awful statins are in one thread while sitting here with sky high triglycerides
dinfar1337
New Member
his cholesterol is worse than mine after 20 week abomb cycle
Just because it doesn’t work for YOU that doesn’t make it a myth. It absolutely is for many including me. The world doesn’t revolve around YOU.
I did not argue that, and I am taking statins. Which mostly lower LDL, the reason I am taking them.
malomkarom
Member
It does work for him. 265 free test and 23 E2. It's very clearly working for him.
Content - Health Encyclopedia - University of Rochester Medical Center
20-50 pg/ml per URMC. You're at the bottom of that. That wouldn't be great in general, but then we have to add on the fact that you're injecting a relatively large amount of exogenous test, have a crushed SHBG, and a huge amount of free test. Your E2 should not be that low!
We don't have a control here to compare against, but that level of E2 in those conditions without some form of AI would be an extreme outlier. Not saying it's impossible, but the conclusions we can reach here are that you are on a very extreme portion of the bell curve, or... primo works as an AI for you.
Like, what is the point of saying that?
Am I blind? Cannot I not read?
Is that not the number 23? Does it not say the reference range is less than or equal to 29? Is the number 23 not less than or equal to the number 29?
Why not simply explain your point of view? What do you gain by writing post after post that is basically saying "Fuck you, retard".
As I said above, there are more sources than I can count on PubMed that detail how DHT lowers SHBG.
This is a reason people use DHT drugs - it raises free testosterone. Is there any way to increase free testosterone to the levels I have WITHOUT using a DHT drug?
Wow.
The world doesn't revolve around ME. Gee thanks for taking the time out of your day to share that piece of wisdom.
I apologize if that was not your intent with the argument. That was one of my takeaways from it all based on your posts.
With that out of the way: Statins do make significant impact on trigs so a 200+ reading is still pretty nuts. I don't have a particularly good diet and my last trigs were 79, largely due to my ancillary use.
Effect of rosuvastatin 5-20mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia - PubMed - 20mg of rosuvastatin resulted in a ~1/3rd reduction of triglycerides.
Sorry, it seems you needed that reminder…
malomkarom
Member
You still don't even try to comprehend what you're reading and arguing with.
Your only argument for why primo doesn't effect E2 is because your E2 is borderline crashed while taking primo. You completely dismiss the whole "effect" part, which happens to be the entire argument you're working against. DO you understand that? Like seriously, do you?
Your saying it isn't effected at all, cause it's in range.
Ever tried cruising at 230-350 test levels? Genuine question.
If you have, you have experience with the fact that the reference range is a warning for serious medical issues, and they don't mean "within this range there's no difference". A 10 point difference in E2 is literally can't get it up to fucking 5 times a day. The real medical reference range for more accurate testing methods is 20-50 in almost all countries. That is a ridiculously large range. Going from 50 to 20, which primo almost certainly did to you is enough of a hormonal jump to literally leave you a delusional, emotionless, numbs piece of meat with no rhyme or reason. I imagine it's getting pretty rough to wake up in the morning, thus the need for the antipsychotics.
Anyways, I'll just have fun talking to the rest of the community in this thread and try to learn and contribute, I'm starting to get over you stubbornly screwing with both your physical and mental health.
You are probably a grown up unless you registered as an infant, you have free will and you are the only one responsible for your health. If your will is ED, apathy and an early death in at most your mid-40s, go get it tiger.
Dude, you are the worst about just saying random shit and pretending it is somehow some sort of argument in your favor.
Am I arguing with you about why your SHBG is low? Am I saying DHT doesn't lower SHBG? I know why your SHBG is low, and DHTs do lower SHBG.
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