Post up your Natty IGF-1 Level

[AlexDavis43]

i even said tia , geez , tough crowd.

I think I was just holding that reply for a while, like other people asking for screenshots when OP clearly had zero incentives to lie

That, combined with the ease of photoshopping almost anything unless it has a verification code like Jano tests...

 

[Ateam2023]

I think I was just holding that reply for a while, like other people asking for screenshots when OP clearly had zero incentives to lie

That, combined with the ease of photoshopping almost anything unless it has a verification code like Jano tests...

ah yes , good ol photoshop, i forgot how easy shit can be manipulated, ok , ill "go SLAP myself in the corner" for being naive, lol

 

[Avies48]

134… it has dropped a few points since my last 138 posting… now my e2 is a tad high right now so that could, maybe, perhaps have something to do with the loss of 2 points… or my body wants to live to be 100… so my igf is slowly decreasing to extend my life… maybe, perhaps, doubtfull

 

[Middus]

134… it has dropped a few points since my last 138 posting… now my e2 is a tad high right now so that could, maybe, perhaps have something to do with the loss of 2 points… or my body wants to live to be 100… so my igf is slowly decreasing to extend my life… maybe, perhaps, doubtfull

My IGF-1 drops along with my e2

 

[Avies48]

My IGF-1 drops along with my e2

Well i did pin test recently and e2 shot up along with total test… but igf… cmon this body of mine sucks haha

My e2 went up and igf went downzies

 

[crispybacon!]

52yo male, 176 baseline IGF. Have been running 4iu for the past 6 weeks and will be testing next week. First time, so I’m interested to see where I land.

 

[Freeboomboom]

My IGF-1 drops along with my e2

Thats correct. Higher e2 = higher igf from your gh.

 

[Ghoul]

Thats correct. Higher e2 = higher igf from your gh.

No. Higher E2=higher GH but
lower GH to IGF conversion. IGF may rise with E2 when it increases endogenous GH; but from exogenous GH, higher E2= lower IGF.

 

[Freeboomboom]

No. Higher E2=higher GH but
lower GH to IGF conversion. IGF may rise with E2 when it increases endogenous GH; but from exogenous GH, higher E2= lower IGF.

Wrong.

Yes, you are whatever study on women you post…

Its obvious you never run the compounds and done bloodwork.

 

[Ghoul]

Estrogen induces a state of GH resistance in the liver. It enhances GH secretion but decreases the efficiency with which GH stimulates IGF-1 production.

Estrogen interferes with GH receptor in the liver, suppressing STAT5b receptor activation, critical for IGF-1 conversion. .

1. Weissberger AJ, Ho KK, Lazarus L. J Clin Invest, 1991

“Estrogen administration was associated with a marked increase in mean serum GH concentrations, but a reduction in serum IGF-I levels, consistent with a state of hepatic resistance to GH.”

2. Leung KC, Johannsson G, Leong GM, Ho KK. Endocr Rev, 2004

“Estrogen attenuates the hepatic actions of GH by inhibiting GH receptor signaling, leading to a reduction in IGF-I generation and a state of acquired GH resistance.”

3. Veldhuis JD, Iranmanesh A, Ho KK. Eur J Endocrinol, 2005

“Administration of estrogen augments GH pulse frequency and amplitude but diminishes the IGF-I response, signifying impaired GH receptor-mediated signaling in the liver.”

4. Ho KK, Weissberger AJ. Metabolism, 1992

“The paradoxical rise in GH with a fall in IGF-I during estrogen exposure represents hepatic GH resistance induced by estrogen.”

Frontiers | Estrogens Regulate the Hepatic Effects of Growth Hormone, a Hormonal Interplay with Multiple Fates

The liver responds to estrogens and GH which are critical regulators of body growth, gender-related hepatic functions, and intermediate metabolism. The effec...

www.frontiersin.org

Beyond the X Factor: Relevance of Sex Hormones in NAFLD Pathophysiology - PMC

Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being frequently associated with obesity, unbalanced dietary regimens, and reduced physical activity. Despite their greater adiposity and reduced physical activity, women ...

pmc.ncbi.nlm.nih.gov

The Influence of Estrogens on the Biological and Therapeutic Actions of Growth Hormone in the Liver - PMC

GH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with ...

pmc.ncbi.nlm.nih.gov

 

[Freeboomboom]

Estrogen induces a state of GH resistance in the liver. It enhances GH secretion but decreases the efficiency with which GH stimulates IGF-1 production.

Estrogen interferes with GH receptor in the liver, suppressing STAT5b receptor activation, critical for IGF-1 conversion. .

1. Weissberger AJ, Ho KK, Lazarus L. J Clin Invest, 1991

“Estrogen administration was associated with a marked increase in mean serum GH concentrations, but a reduction in serum IGF-I levels, consistent with a state of hepatic resistance to GH.”

2. Leung KC, Johannsson G, Leong GM, Ho KK. Endocr Rev, 2004

“Estrogen attenuates the hepatic actions of GH by inhibiting GH receptor signaling, leading to a reduction in IGF-I generation and a state of acquired GH resistance.”

3. Veldhuis JD, Iranmanesh A, Ho KK. Eur J Endocrinol, 2005

“Administration of estrogen augments GH pulse frequency and amplitude but diminishes the IGF-I response, signifying impaired GH receptor-mediated signaling in the liver.”

4. Ho KK, Weissberger AJ. Metabolism, 1992

“The paradoxical rise in GH with a fall in IGF-I during estrogen exposure represents hepatic GH resistance induced by estrogen.”

Frontiers | Estrogens Regulate the Hepatic Effects of Growth Hormone, a Hormonal Interplay with Multiple Fates

The liver responds to estrogens and GH which are critical regulators of body growth, gender-related hepatic functions, and intermediate metabolism. The effec...

www.frontiersin.org

Beyond the X Factor: Relevance of Sex Hormones in NAFLD Pathophysiology - PMC

Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being frequently associated with obesity, unbalanced dietary regimens, and reduced physical activity. Despite their greater adiposity and reduced physical activity, women ...

pmc.ncbi.nlm.nih.gov

The Influence of Estrogens on the Biological and Therapeutic Actions of Growth Hormone in the Liver - PMC

GH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with ...

pmc.ncbi.nlm.nih.gov

”Estrogen administration”

Estrogen from aromatization of injectable testosterone increases the conversion of exogenous GH to IGF-1.

 

[Cyp180]

52yo male, 176 baseline IGF. Have been running 4iu for the past 6 weeks and will be testing next week. First time, so I’m interested to see where I land.

Natty means no HGH use i think ?

 

[crispybacon!]

Natty means no HGH use i think ?

Sorry. I could have been clearer. 176 is natty, measured ~6 weeks ago before starting HGH for the first time. I will be getting bloodwork done next week to see where 4ius is putting me.

 

[Middus]

”Estrogen administration”

Estrogen from aromatization of injectable testosterone increases the conversion of exogenous GH to IGF-1.

I haven't recovered from all the acromegaly hot takes.
All I know is that my blood tests agree with what you stated.
My e2 levels have been positively correlated with my IGF levels from tests.

 

[kvfla]

Before starting HRT my serum IGF-1 was zero. I got an rx for GH but insurance doesnt cover it, its well over $1k/month. My T was 64 and my E2 was 4. The only noticeable symptom I had was no sex drive. I was 6'2" 180, very lean athletic build. Once starting HRT my lean mass (and appetite) shot up, so apparently frailty was a symptom. Doctors have no explanation for why my levels were so low. I don't have a detectable tumor.

 

[Middus]

Before starting HRT my serum IGF-1 was zero. I got an rx for GH but insurance doesnt cover it, its well over $1k/month. My T was 64 and my E2 was 4. The only noticeable symptom I had was no sex drive. I was 6'2" 180, very lean athletic build. Once starting HRT my lean mass (and appetite) shot up, so apparently frailty was a symptom. Doctors have no explanation for why my levels were so low. I don't have a detectable tumor.

FWIW, my IGF dropped after I started 3IU daily GH. I'm not going to fight it.. My Body has done it's best to keep me alive. Not going to argue too much with it if I have no neg signs or symptoms

 

[DeodatoFulci]

90 ng/mL reading before my current 1iu daily of Titan HGH. 2 weeks in thus far, and i plan on titrating up to 2 iu in a few weeks.

 

[burner18]

41 yrs
3rd week of 1mg Tesamorelin/300mcg Ipamorelin
214ng/ML

 

[sionnach]

90 ng/mL reading before my current 1iu daily of Titan HGH. 2 weeks in thus far, and i plan on titrating up to 2 iu in a few weeks.

Shit. 90 is wild. What was your pre-GH baseline?

 

[Alvinq]

Shit. 90 is wild. What was your pre-GH baseline?

Is that not the baseline? Maybe I'm interpreting his post wrong.