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"Nonprescription drug" is not the same as "over the counter". It's a prescription drug that can be supplied by the pharmacy without a prescription if you qualify. Among other drugs, tadalafil (cialis) will be one of the first.

A step in the direction of pharmaceutical liberty.

www.fda.gov

7 Things to Know About the Nonprescription Drug Product with an Additi

7 Things to Know About the Nonprescription Drug Product with an Additional Condition for Nonprescription Use Final Rule
www.fda.gov www.fda.gov
 
wp_375 said:
Ironic because Dayvigo isn't really conducive to recreational abuse like the Z drugs are... But still controlled, cause reasons. LOL

We need Trump and RFK to start de scheduling stuff that shouldn't be controlled like steroids, Modafinil, etc.
Click to expand...
What does Indian Dayvigo sell for? Interested in trying a DORA but not paying USA pharma prices.

No good reason why they should be scheduled.
 
bigdaddyandfriends said:
What does Indian Dayvigo sell for? Interested in trying a DORA but not paying USA pharma prices.

No good reason why they should be scheduled.
Click to expand...
I paid the below. It was seized and now my guy doesn’t want to risk reship. But it was a good price I think.
Dayvigo 5mg x 140 pills---$107.5
Dayvigo 10mg x 140 pills---$155.5
 
Ghoul said:
In my opinion it's the best for that purpose. Super low chance of any sides, *uniquely* among statins it boosts HDL count and *function* (an overlooked factor, poor quality HDL is worse than low quality). It IMPROVES insulin resistance rather than reducing it. Doses are minuscule. 4mg is the top dose equivalent to 20mg Crestor.

View attachment 345083View attachment 345081

If 4 mg doesn't bring LDL below 70, you can add Ezetimebe, another near zero side effect LDL lowering compound to lower it further. You can ask for that on telehealth as well. By the way, once you have a prescription bottle in hand, it's easy to come up with a story about how you got it (I got paranoid about all my relatives who died from heart attacks so called a telemedicine doctor to discuss my lipids) and any PCP will generally be willing to pick up the prescription from there.

If you tell them it's working well for you, they have no reason to object. Another doctor "greenlighting" a med eliminates resistance to PCPs prescribing it.

I've done this numerous times for daily cialis, oral minoxidil, finasteride, etc.
Click to expand...
The problem with all LDL reducing drugs is that it also reduces total cholesterol and thus reducing your total testosterone. Its not a problem if youre on TRT but when ur natty you can def feel a difference. From my own experience if my total chol goes below 5.2 mmol/L I start to feel shittier.
 
bigdaddyandfriends said:
What does Indian Dayvigo sell for? Interested in trying a DORA but not paying USA pharma prices.

No good reason why they should be scheduled.
Click to expand...
I got some from PCT delivered about a week ago, 14 x 10mg tabs was $18. One 10mg tab zonked my 235lb ass with some residual drowsiness the next day. Going to try half a tablet and see how that feels. Seems on par with 3mg eszopiclone but the eszopiclone doesn't leave me drowsy after I wake up.

I'm trying to have a few different sleep meds on hand that all work so I can cycle through them and not take any one long enough to get tolerant (or dependent) of it. Got some trazodone and zaleplon too to try
 
Photon said:
Around $6-8 MSRP for a strip.
US Pharma prices is 10$ for a month as long as you have commercial insurance coverage.
Click to expand...
You all got docs that will prescribe sleep meds? Mine basically said they won't prescribe them and just said sleep issues will improve on their own if your sleep habits are good. Fuck me I guess :D
 
john87412 said:
The problem with all LDL reducing drugs is that it also reduces total cholesterol and thus reducing your total testosterone. Its not a problem if youre on TRT but when ur natty you can def feel a difference. From my own experience if my total chol goes below 5.2 mmol/L I start to feel shittier.
Click to expand...

Not questioning your sensitivity to T levels, but to ensure this stays in context and freak outs are avoided (this is Meso after all) the largest meta study analyzing 30 others, involving tens of thousands of men, taking the most extreme scenario, reducing LDL below 40mg/dl (1 mmol/) only resulted in a 2-5% drop in total T, no change in Free T (or any other sex hormone).

A fraction of 1% experience a 15% drop in total T (the toughest drop recorded).

Day to night variation in total T is 30%, and hour to hour in the daytime can be 15%, so 2-5% is considered clinically insignificant and not something that could be "felt" unless someone was borderline hypogonadal. Changes in Free T are much easier to sense, as low as 5%c, but lowering lipids doesn't affect it.

Anyway, it's good to be aware it's possibility that might affect some rare outliers, but for the overwhelming majority a non-issue, (Leydig cells make cholesterol when needed to produce testosterone when it's not in blood, but it's possible some have a dysfunction preventing that).

Do statins decrease testosterone in men? Systematic review and meta-analysis - PMC

Statins are one of the most prescribed classes of drugs worldwide to treat hypercholesterolemia and dyslipidemia. By lowering the level of cholesterol, the use of statin could cause a reduction in testosterone levels. The objective was to evaluate ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
Ghoul said:
Not questioning your sensitivity to T levels, but to ensure this stays in context and freak outs are avoided (this is Meso after all) the largest meta study analyzing 30 others, involving tens of thousands of men, taking the most extreme scenario, reducing LDL below 40mg/dl (1 mmol/) only resulted in a 2-5% drop in total T, no change in Free T (or any other sex hormone).

A fraction of 1% experience a 15% drop in total T (the toughest drop recorded).

Day to night variation in total T is 30%, and hour to hour in the daytime can be 15%, so 2-5% is considered clinically insignificant and not something that could be "felt" unless someone was borderline hypogonadal. Changes in Free T are much easier to sense, as low as 5%c, but lowering lipids doesn't affect it.

Anyway, it's good to be aware it's possibility that might affect some rare outliers, but for the overwhelming majority a non-issue, (Leydig cells make cholesterol when needed to produce testosterone when it's not in blood, but it's possible some have a dysfunction preventing that).

Do statins decrease testosterone in men? Systematic review and meta-analysis - PMC

Statins are one of the most prescribed classes of drugs worldwide to treat hypercholesterolemia and dyslipidemia. By lowering the level of cholesterol, the use of statin could cause a reduction in testosterone levels. The objective was to evaluate ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
Click to expand...
Yes Ive seen this study however the reality is different, theres many threads on reddit of guys using statins and they said that they no longer get morning wood and have less libido and that after they quit the statin they returned back to normal, I had the same experience. It could be related to something else because the same thing happened to me even when I was on test. I just dont believe there is a drug without side effects, sometimes we just cant observe them yet.
 
wp_375 said:
I got some from PCT delivered about a week ago, 14 x 10mg tabs was $18. One 10mg tab zonked my 235lb ass with some residual drowsiness the next day. Going to try half a tablet and see how that feels. Seems on par with 3mg eszopiclone but the eszopiclone doesn't leave me drowsy after I wake up.

I'm trying to have a few different sleep meds on hand that all work so I can cycle through them and not take any one long enough to get tolerant (or dependent) of it. Got some trazodone and zaleplon too to try
Click to expand...
It’s interesting how people respond differently to sleep meds. A few pages back I could’ve sworn I saw someone say Dayvigo was disappointing for them. I also read a thread here comparing Lamborexant(Dayvigo) with Daridorexant and supposedly Daridorexant is superior on paper.
 
Tkjo said:
It’s interesting how people respond differently to sleep meds. A few pages back I could’ve sworn I saw someone say Dayvigo was disappointing for them. I also read a thread here comparing Lamborexant(Dayvigo) with Daridorexant and supposedly Daridorexant is superior on paper.
Click to expand...
It was Quviviq. Similar but newer medication. Both are selective orexin-2 receptor antagonists. For me it was disappointing. The first few days it made me sleepy and kept me asleep 7-7.5 hours. But after a few days it started preventing me from sleeping. One night I took 900-1,200mg of Gabapentin to try and fall asleep and Quviviq wouldn’t let me fall asleep. I say 900-1,200 because I was mad out of my mind and lost count. It took about 3-4 days to get it out of my system so I could sleep normally again.

I ordered Dayvigo just before I was able to get prescribed Quviviq but it was seized by Customs. I wasn’t planning on trying it out anyway after my Quviviq failure.
 
Just got prescribed quviviq. My sleep has been horribly fragmented for months. Don't think I've slept over 6 hours total in 8 months and average 5 or less. Last few days trying quviviq I'm still fragmented but can get back to sleep. Slept more than 7 hours 2 days in a row. Probably been over a year since I've slept that long.

Hopefully it keeps working and I don't have the same problem in a few days.
 
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