Clappincheeks
Member
Are you saying taking a smaller amount will equal better results?
MESO-Rx
Anabolic Steroids
Post up your Natty IGF-1 Level
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Ateam2023
Member
Definitely get a gh serum test , do 10 iu bolus test within 3 hrs and report back , that will give you a good idea how "potent" for lack of a better description,,
Ateam2023
Member
have you done a gh serum test with the current "magic potion" hgh you have? I would want to know myself, that is an insane response,
Ghoul
Member
No, if all other factors stay the same, IGFBPs increase proportionately with rHGH dose, and absolute free IGF still increases (or decreases with lower dose).
The amount of IGFBP production relative to IGF is increased by a bunch of potential factors. High estrogen, high liver enzymes, low insulin (from a very low carb diet or diabetes), oral AAS, kidney problems, using too much T3/T4, high cortisol, etc. Cumulatively the difference in IGF activity could be huge. At the same total IGF-1, .1% vs .3% free IGF would have dramatically different results.
songsofpyramids
Member
That’s a huge dose lol. That said, I would not be shocked if 3iu beats out in practice whatever the cjc was doing regardless of igf1 test. There’s a lot of downstream action hgh does that aren’t readily measured. I guess mod grf could as well, but I’d be very hesitant to blast that much myself.
Not yet, that was just an IGF test I did during my last bloodwork. But next time I’ll definitely add a GH serum test and see what the results look like.
Proud Pangolin
Member
Not necessary as you can see by this case. To be fair he was taking Nova which is known to lower igf-1 like every SERM but on the other hand its 6 IU
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Proud Pangolin
Member
I really never got the "im a great responder because my systemic igf-1 is high" arguement. Because for anabolism autocrine igf-1 levels are relevant not endocrine igf-1 levels.
Actually there even is a negative connection between those two. Meaning high endocrine igf-1 will result in lower autocrine igf-1. The relation is more complicated though as at some point the relation changes meaning if the endocrine igf-1 is high enough it will overturne the negative correlation witg autocrine igf-1 and increase autocrine igf-1.
No doubt.. lol.
That's why I've neither stepped up my Current GH dose nor have I dropped GH.
as @Proud Pangolin Pointed out, Circulating IGF-1 is just a piece of the puzzle and sometimes doesn't even correlate with IGF-1 levels in muscle interstitial fluid. That's why some pros say in an ideal world, muscle biopsy (ideally microdialysis, but tall horse) would be a more accurate test.
@Proud Pangolin I attached the article.
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Proud Pangolin
Member
I want to add something:
For some reason i react VERY VERY GOOD on GHRP-2 + CJC no DAC 3x times a day (before fasted cardio, right after training,before bed)
Really doesnt make sense. This shouldnt be. I look like on cycle.
My only explaination isy that dues to the pulsative GH from the peptides autocrine igf-1 is primarly eleveted.
I have no systemic igf-1 levels yet bit thats not really what matters. What matters is "anabolic you react" to a compound. Of course this is problematic due to subjective perception so every sceticism is totally understood. And im also just one case, obviously formmoat people it seems that peptides dont result in a anabolic response at all.
songsofpyramids
Member
@Proud Pangolin I tightened up and looked fuller on 3-5 ipa x mod grf shots a day too too. That’s not crazy or extreme. It makes you hold water in a nice way so your muscles look fuller without edema. You only ran hgh for 6 weeks which is basically nothing, and you didn’t jump right to 4iu did you? I promise you you’re not special enough that ghrh and ghrp are going to work better for you than hgh when we have a decade and a half of testing and anecdotal information saying it’s not as potent as hgh. It’s great you’re getting benefit out of it. How long you been running ghrp 2? How’s your prolactin doing on it?
Proud Pangolin
Member
Yes i actually did jump to 4IU directly and i actually tolerated it pretty good to my surprise (besides soke bloating) but it fucked up my sleep to much which was already bad enough before.
However this doenst mean i wouldnt react better or the same with HGH. In general i just reacted very well to the igf-1 i guess. Which totally surprised me because "GH only cycles" are often perceived as not worth it. Or you can read stuff like "4IU arent really that anabolic, bodybuilding dosages START at 6IU".
Well i can tell you that these peptides are damm anabolic for me, so anabolic that i didmt hop on cycle as planned 4 months ago because i wanted to see how this is going.
However as i mentioned in multiple other post about this, im comparing apples with bananas. Because last year during my 600mg test + 600mg DHB NOTHING was in line:
- extreme stress
-sleep was at least to say HORRENDOUS
(was going to bed at 1 am, waking up 3h later and not beeing able to fall asleep for at least 2h just to give an example)
-dient eat enough, diet was off (because of my stress and E2-> i was an idiot all you need to know)
-training was also off because my ex had a talent starting fights while i was at the gym and me as an d idiot did actually fight via phone (totally my fault)
=> So im comparing my anabolic response of this heavy cycle (600mg of DHB is some strong shit, cosnidering that stuff is like 2x stronger than Primo/EQ)
with my "Peptide cycle" right now where everything is on line. Sleep, diet, training,stress all almost optiomal right now.
So while im totally sure (based on feedback from extern sources like my couch who is a antique roid head) that im a great anabolic responder to igf-1/ GH, who knows how good i would react in the same circumstances on 600mg test and 600mg DHB.
There is also the possebility that the GH was underdosed as i sources that GH from some gym source and not one of the established sources on the forum.
Lots of words.... I just wanted to point out that this isnt me beiing "im had this crazy results n peptides, who still needs steroids?!" I just wanted to point out that i had/have a rather very untopical strong and not expected reaction on peptides
songsofpyramids
Member
I do solo hgh and put on about twice as much muscle and drop about twice as much fat per month than without according to dexa. That’s even hovering around 2.8iu. The body comp, recovery, and positive mental affect from hgh are the shit. You won’t grow like a monster like with oils, but it is definitely doing shit that looks and feels good.
bigforyouben
Member
IGF update: 53M, 6 months alcohol free, steady weight around 205#, 10-12% BF. 4iu GH for the last few months. IGF-1: 283 ng/ml (1.6 z score).
Due to carpal tunnel symptoms I had quit GH for a while, but CTS persisted. I had the release surgery two months ago and my fingers feel like fingers again (even on 4iu GH)
Due to carpal tunnel symptoms I had quit GH for a while, but CTS persisted. I had the release surgery two months ago and my fingers feel like fingers again (even on 4iu GH)
Ghoul
Member
bigforyouben
Member
Yes, I've had symptoms on and off for years. It seemed to get worse when I started GH but didn't get better when I stopped, so it may have been natural progression. The nerve study showed "moderate to severe" carpal tunnel syndrome and the surgeons thought I needed surgery asap (of course). I am glad I took a little extra time to find a surgeon to do it orthoscopically because it has healed about as quickly as anybody could hope for.
It’s been about 6 days without GH since I left for vacation and I’m already 2 lbs lighter, probably just extra water dropping off. My head even feels lighter somehow, hard to explain. Sleep is surprisingly better, heart rate is down, and so far I don’t feel any crash at all… not sure if I ever will. Thinking I might take a full month off and then jump back on, maybe. Who knew taking a break could feel this good… almost suspicious.
Ateam2023
Member
i was wondering what " taking a break" from hgh would do or "feel like"? Anyone else with experience "coming off hgh" for a little while can please let us know your experience, Tia,,
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