Random Collection of Questions

[oldguy619]

Bioavailable T is free T plus HSA (human serum albumin) bound.

Total T is the above plus SHBG bound T.

If you had your free T measurement using equilibrium dialysis it would be easier to discuss.

Interesting enough I asked my doc about this as he pushed for the bio versus free. He responded to me with your free t is 7.5 nmol/l 216ng/dl.

 

[readalot]

Understood, I'll read what you have directed me to. What my ask is , I went back and looked I was off my a hair. 180.9 Bioavailable Test out of 197 Total T. That's seems amazingly high for it not to be influenced by something? My previous tests are no were close to 91% available when Mast was not in the mix. Again not trying to argue im trying to understand and maybe I just need to go read.

That albumin number and ref range dont compute for me.

Here is how your bioavailable T is calculated. Check the math...

Free & Bioavailable Testosterone calculator

Essentially your TT is through the roof and your SHBG on the lower side.

 

[oldguy619]

I attached the lab results a couple posts back.

 

[readalot]

That albumin number and ref range dont compute for me.

Here is how your bioavailable T is calculated. Check the math...

Free & Bioavailable Testosterone calculator

Essentially your TT is through the roof and your SHBG on the lower side.

My apology. Your units are g/L. My bad @oldguy619.

Yes you can use the Vermeulen calculator above to estimate your free T.

 

[oldguy619]

So thoughts on my results and masteron's impact on SHBG and free Test? Especially if I am not accurate in my thinking/speaking. My doc's comment right away was your are clearly on a DHT as well. Recognizing he isn't necessarily an expert but is a private doc that handles enhanced clients.

Appreciate the discussion

 

[readalot]

216ng/dl

I come up with whopping 240 ng/dl free T using Vermeulen. About 10x the typical upper reference range using equilibrium dialysis. You are up there!! TT = 5681 ng/dl.

 

[readalot]

So thoughts on my results and masteron's impact on SHBG and free Test?

You are running a shit load of test and your SHBG is on lower end. Was your TT measured using LCMS?

Your test dose sets your FT. Your SHBG plus FT then set your TT.

 

[oldguy619]

600 test 600.mast.

 

[readalot]

600 test 600.mast.

Yep. You are where I would expect you with SHBG on the lower side. Your TT measurement most likely is LCMS. Very cool.

R

Post in thread 'Tool to Assess your TT dose response --Percentile Curves'

Oct 5, 2023

Linear version of graph....
You can use regression equations from Bi 2018 study to get low, mean, high estimates for TT level vs weekly equivalent dose.



Here’s the mean TT level (ng/dl) for 70. mg/week of Test Cypionate (see equations on chart below):

2.5 percentile response = 360
50 percentile response = 630
97.5 percentile response = 1200

Don't forget to use this table to convert your blood work result (trough) on given dosing protocol to mean:


Table: conversion between peak/trough/mean for first order absorption/elimination PK model assuming 4.5 day elimination...

• readalot

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[oldguy619]

No primo around so playing with mast on my e2. Not great results for me which I expected but was hopeful

 

[readalot]

No primo around so playing with mast on my e2. Not great results for me which I expected but was hopeful

I ran 400 mast e with 400 test c and I am still recovering. My prostate gained wonderfully. I am no mast fan. Glad it works for some.

 

[oldguy619]

Not good. I seem to be doing ok. No symptoms and PSA was 1.0

 

[readalot]

Not good. I seem to be doing ok. No symptoms and PSA was 1.0

My PSA stayed at 0.45 but prostate still exploded.

Nice chatting with you.