The pharma doses are 2,4,8,12.
Considering the average LDL reduction at 12mg was only 22%, in multiple large clinical trials, it'll be very surprising if yours drops significantly at 1mg. Also, familial hypercholesteremia (FH) doesn't respond very much to GLPs because the root cause is genetic. The mechanism (LDL clearing receptors) in the liver that removes LDL from blood is broken in FH, and Reta or any other GLP won't fix that.
I hear what you are saying but I stand by my previous claim, that these studies are of limited use, for someone with BMI of >30 while bein not too far from being at a single digit amount of BF, let alone a real BB (which I am currently certainly not).
These studies were literally done with people that have multiples of pure fat weight stuck on their bodies, and sometimes maybe not much more than half of just my muscle mass (which is more at the lower end for anyone in this sport).
I am not sure what the goal is then of OP here. Many people gave good examples esp. with lipid management.
Is he looking for confirmation that a dose below clinical trial use to fix lipid issues or what?
Will Retra help improving lipids? Eventually, at 1.5mg i wouldn't even bother pinning. 4mg Retra, some ezemtib and pitavastin or bempoic acid and it should be fine
I asked for the effects of Reta on LDL and overall lipids, never was I asking for confirmation that my experiment with subclinical doses will lead to me having LDL like a virgin. Would you provide a quote of mine, to back up your assesment?
I might still have it, but I was never diagnosed with FH by any physician, so don't treat it as a given just because Ghoul said so...
And yet we have Anabolic BB,
@madcap71 and (presumably because he hasn't confirmed that yet)
@juicybanana69 showing noticeable improvements to their lipids, at subclinical, or very low clinical doses, while being on a similar mg of gear, as I am, and living a similar lifestyle.
30% in my case would mean getting close to a LDL of 100, where one can argue that no further medication is necessary.
And why would I ever want to take 4mg of Reta? Did you even bother to actually read any of my posts? Do you see >me<, a self-described terrible eater, eating 5000+kcal of clean food on 4mg of Reta?
Like mentioned, I had already looked into Ezemtibe and statins, long before opening this thread, as having written in my first reply to Ghoul, so I am not sure what tree you are actually barking at.
There is reading studies and having real world experience:
Women were given 1200mg of Primo for breast cancer. At this dose, you would see me (or many other guys in this forum) grow almost by the day. In fact, I would still grow even if I were just riding my bike and doing yoga. I am bigger* than many, if not most, guys in a commercial gym without even really weight training, I was more than once asked, if I am actually competing.
So, what does that study tell us about me, and why do you think that I, or any other real BB for that matter, would react similarly to Reta as people with severe metabolic disease, whose bodyfat is likely north of 50%?
Well, if you're on the max 12mg dose, that is one months worth. If you buy into the "don't keep vials reconstituted for more than a month" because Pfizer says so, 50mg is perfect for that purpose.
Ok, point taken. I still cannot fathom anyone needing that amount that is member of this forum. Other than just being here for sourcing, and not in this sport to some extent.
*No, I am not at allclaiming to be big, but we all know the standards in these kind of gyms...
