Boldenone and low dose DHB?

[Banana Joe]

I haven't found anything much on this topic except (1), and the EQ steroid profile also doesn't really seem to cover that topic - so it probably is a moot discussion. But I keep wondering about it:

Since DHB is 5-alpha-reduced Boldenone, but B only 5ar by probably way less than 10% to DHB, has anyone ever considered adding DHB, at a low ratio of let's say 5:1 or maybe even 10:1?

Will a ratio between 5-10:1 noticeably enhance the effects of Boldenone? And if it does, wouldn't it be just more economic in terms of effects and side effects to add more Boldenone until the same amount of anabolism is achieved?
I assume DHB will tank E2 way more per mg than B, but u can manage that if necessary.

Do we know anything how much B actually is converted to DHB? I was not able to find anything. I remember Kurt Havens might have mentioned something about it on Vigorous Steve's channel, but I might be mistaken.


What is your guys take on this?

 

[eery]

How would it "enhance" the effects of boldenone? it would enhance your cycle by giving you more milligrams and effects of the DHB(?) but i dont see it doing anything to boldenones effects.

EQs AI effect seems to be so individual that its impossible to say much. Some guys estrogen crash very easily, some guys dont get effected at all. DHB doesnt have much of an effect on estrogen from what ive seen.

Ive heard people like Todd lee claim that boldenone converts 25% into DHB, but i have never seen anything or anyone agree with that claim or anything to back it up. I dont think boldenone converts much to DHB at all personally.


ive ran 1g EQ with 1g test and i had none of the effects i get from DHB. Thats just a "feels report" though, so not very useful.

For example, DHB at 50-280mg makes me sick and lethargic after about 1-2 weeks every time ive tried it and ive never experienced that with EQ or any other AAS.


Try a combination of boldenone and DHB and report back

 

[Banana Joe]

How would it "enhance" the effects of boldenone? it would enhance your cycle by giving you more milligrams and effects of the DHB(?) but i dont see it doing anything to boldenones effects.

By being a direct metabolite of Boldenone. From what we know many of these drugs have efficacious metabolites.
DHB is clear proof of that.

EQs AI effect seems to be so individual that its impossible to say much. Some guys estrogen crash very easily, some guys dont get effected at all. DHB doesnt have much of an effect on estrogen from what ive seen.

I have seen people say the opposite. As in it is a drug that has similar properties in affecting E2 like Primo and Mast - which would make a lot of sense as they are all DHT-derivatives and AFAIR there was that one video by Todd, where he shows that Primo and DHB are structurally very similar, so similar effects in terms of E2 should not be entirely surprising (if true - given the source for this claim!).

Ive heard people like Todd lee claim that boldenone converts 25% into DHB, but i have never seen anything or anyone agree with that claim or anything to back it up. I dont think boldenone converts much to DHB at all personally.

At this point nobody should take anything that this guy says as serious information, but simply as edutaimnent at best.
This guy has zero credibility whatsoever. He has refuted himself many, many times. But I am not gonna put in the time and effort to go through his videos to prove that.

ive ran 1g EQ with 1g test and i had none of the effects i get from DHB. Thats just a "feels report" though, so not very useful.

For example, DHB at 50-280mg makes me sick and lethargic after about 1-2 weeks every time ive tried it and ive never experienced that with EQ or any other AAS.

Assuming there is a 5ar of only a few percent and the Boldenone or other metabolites than DHB will "buffer" feeling sick and lethargic I would not read much into the fact that you haven't gotten the same ill effects at 1g of EQ.
We know for a fact that EQ works because it is a derivative of Test. And we know that mg for mg Test is (a lot?) more potent.
There is not much stuff to find about (other than Test) steroid metabolites AFAIK. Kurt Havens has claimed there was a recent paper that showed that Primo has many more metabolites we didn't even know about so far. I was not able to find that paper with a quick search.
1g of EQ might only be 30mg of DHB and a whole lot of other molecules that fix the side effects of that amount of DHB.
But I am also just speculating here, that is why I had opened this topic.

Try a combination of boldenone and DHB and report back

If nobody tells me that my idea is very stupid and gives me a good reason I very likely will do in the foreseeable future.
But my feelz report will be of very limited use for most, as my doses are mostly so low, many would not even consider it a real cycle.

I might try 3-400mg of Bolde C and 30-50mg of DHB added to my generous HRT protocol. I have only used Bolde once, but it was at a dose of 2-300mg, so the only takeaway from that dose was that it is an anabolic compound, but I should have gotten the same anabolism from a similar dose of Test, Primo or Mast.

 

[Dafty]

EQ does not 5ar reduce to DHB in any meaningful way in the body. The fact it's called DHB is abit of a misnomer.

However adding EQ and DHB to a cycle works well - but only in so much as stacking any efficacious anabolic with something that drive CNS will have a mutually beneficial outcome

 

[Banana Joe]

EQ does not 5ar reduce to DHB in any meaningful way in the body. The fact it's called DHB is abit of a misnomer.

However adding EQ and DHB to a cycle works well - but only in so much as stacking any efficacious anabolic with something that drive CNS will have a mutually beneficial outcome

So you are saying that I could equally take Primo or Mast at a similar dose than Boldenone and add 50mg of DHB to that - to get a very similar result?
What data supports Boldenone not reducing to DHB in a meaningful way via 5ar?

I can't see it being a misnomer though, it literally is Dihydro-Boldenone, isn't it?
Same way Dbol is actually Methylboldenone, if I am not mistaken, but these two compounds have nothing in common at, other than both being anabolic.

 

[Photon]

EQ does not reduce to DHB.
I believe adding EQ to anything can help with PIP, especially since DHB gives PIP.
I have not tried DHB(Cyp) but I've tried DHB(Ace) and the PIP was horrifying. I don't think I'll be touching DHB anytime soon. I've not seen any source sell DHB(Ace) yet but raws are still available on the market for it.

MESO-Rx Exclusive Post in thread '1-Testosterone (DHB): Effects, Risks, and Hepatotoxicity'

Feb 16, 2025

The increase E1(estrone) is interesting. We know a metabolite of Boldenone is 5AR to 1-Testosterone. I wonder if this same reduction is what DHB and Boldenone have in common for increasing E1 and in some individuals lowering E2.

It’s not, actually!

Boldenone (EQ) doesn’t 5α-reduce to DHB in vivo in man. [1]. It's part of the reason why I'm very careful to designate it by its name from the nomenclature, 1-Testosterone (1-Test; 1-Testo).

Boldenone singularly produces 5α-androst-1-ene-3,17-dione in vivo in man, in only minuscule amounts since it is so resistant to...

• Type-IIx

• 

Dihydroboldenone Insights: Unique Characteristics of Anabolic-Androgenic Steroids – Part 9

Explore the unique benefits of DHB bodybuilding special uses for enhancing muscle growth and performance in athletes.

thinksteroids.com

 

[Dafty]

So you are saying that I could equally take Primo or Mast at a similar dose than Boldenone and add 50mg of DHB to that - to get a very similar result?
What data supports Boldenone not reducing to DHB in a meaningful way via 5ar?

I can't see it being a misnomer though, it literally is Dihydro-Boldenone, isn't it?
Same way Dbol is actually Methylboldenone, if I am not mistaken, but these two compounds have nothing in common at, other than both being anabolic.

At an equal dose (mg for mg), no - because drugs have different levels of efficiency or "potency". But at an equivalent dose, yes. Primo + DHB would give broadly the same output as EQ+DHB from a muscle building perspective. There may be slight differences in transient aesthetic impacts due to compound selection.

See post above for citations regarding EQ not 5-ar reducing to DHB in body. As far as I am aware EQ does not interact with 5-ar at all.

 

[Banana Joe]

EQ does not reduce to DHB.
I believe adding EQ to anything can help with PIP, especially since DHB gives PIP.

Well, I had never heard that before, but I must admit to not have read (or even known about it) the new DHB profile in the portal.
Interesting! One might argue, that you then have to take DHB as it is just a replacement for your body's inability to 5ar Boldenone, haha!
I premix all my shots of different anyway, I don't think I ever had PIP since I do that. But yeah, adding a no-PIP oil always helps to to mitigate the PIP from any oil.

I have not tried DHB(Cyp) but I've tried DHB(Ace) and the PIP was horrifying. I don't think I'll be touching DHB anytime soon.

I had bad PIP from Test Ace, because curiosity got me and I wanted to try that rare ester. Since then I stick with long esters like Enanthate, Cypionate, etc. because I see no advantage in using short esters for my kind of application. If I do a blast, I just frontload to some extent and am good.

 

[Banana Joe]

At an equal dose (mg for mg), no - because drugs have different levels of efficiency or "potency". But at an equivalent dose, yes. Primo + DHB would give broadly the same output as EQ+DHB from a muscle building perspective. There may be slight differences in transient aesthetic impacts due to compound selection.

See post above for citations regarding EQ not 5-ar reducing to DHB in body. As far as I am aware EQ does not interact with 5-ar at all.

Of course, that is why I wrote "similar dose" as mg for mg they are not all equally potent.
I had never solely looked at compounds from this perspective, but when you say something that drives CNS, what other compounds are there, that are NOT a 19-Nor, mainly Tren or Trest, or an injectable version of an oral DHT-derivative like Anadrol, Sdrol, etc.?

I would be still curious about the real world toxicity of DHB at doses of 50-150mg. I am perfectly happy with 70mg of Tren in a 1g blast, so I doubt I would want to use more than 100mg of DHB.

 

[Dafty]

Of course, that is why I wrote "similar dose" as mg for mg they are not all equally potent.
I had never solely looked at compounds from this perspective, but when you say something that drives CNS, what other compounds are there, that are NOT a 19-Nor, mainly Tren or Trest,
or an injectable version of an oral like Anadrol, Sdrol, etc.?

I would be still curious about the real world toxicity of DHB at doses of 50-150mg. I am perfectly happy with 70mg of Tren in a 1g blast, so I doubt I would want to use more than 100mg of DHB.

To varying degrees:

Mast
Test
Halo
Cheque drops
Tren
DHB
Winny
Clen (not an aas but underrated for strength)

 

[bigdaddyandfriends]

I started DHB beginning of Sept. just 15mg/day. No front loading but I started noting significant stength gains after about a week.

Zero PIP and feeling fine so far. Seems like primobolan but much better and much more potent; and it is primobolan sans the c1-methyl group.

 

[Banana Joe]

I started DHB beginning of Sept. just 15mg/day. No front loading but I started noting significant stength gains after about a week.

Zero PIP and feeling fine so far. Seems like primobolan but much better and much more potent; and it is primobolan sans the c1-methyl group.

15mg ed seems like a sensible dose. Let us know how it goes. I am still wondering if I should give it a try, but not sure if I am better off with just EQ or Primo. EQ is so much cheaper, and their side effect profile seem favourable, when being compared to DBH.

QUOTE="Dafty, post: 3534876, member: 122499"]
To varying degrees:
....
[/QUOTE]
Forgot to say thanks!

 

[bigdaddyandfriends]

15mg ed seems like a sensible dose. Let us know how it goes. I am still wondering if I should give it a try, but not sure if I am better off with just EQ or Primo. EQ is so much cheaper, and their side effect profile seem favourable, when being compared to DBH.

QUOTE="Dafty, post: 3534876, member: 122499"]
To varying degrees:
....

]

Still early for me being a cyp ester, but I say give it a try - assuming you have good DHB.

I replaced 30mg/day primobolan enanthate with 15mg/day DHB cypionate Sept 1 - and also 30mg/day boldenone, but that's for my winter cruise). So while I did increase my total anabolic load by 15mg/day, the EQ is still rising slowly in my system and nearly half of those extra mg are from the heavy undecylenate ester.

By end of first week I noticed significant strength gains, and I didn't change anything else in my regimen. I had been at a plateau for a long time and really wasn't trying to break through it at 57 yo. I was being very careful not to hurt myself in the gym as this seemed to be the perfect setup for an injury; but I've increased the weights on all my exercises.

As I've mentioned on various threads here, I have used primobolan many times and it has underwhelmed me, neither giving much estrogen control or anabolism - it seems to be highly weakened compared to testosterone. Its major metabolites are indeed 3⍺-hydroxylated which implies it only has partial resistance 3⍺-HSD, which breaks down DHT-like androgens in skeletal muscle. Not going to claim I know all its metabolites as I do not, but one of them is not atamestane (a non-competitive AI like aromasin). I believe Kurt was quoting a study of fungal metabolites of primobolan, which are completely different than human - all steroidal AIs have a double bond between C1-2 and C4-5, and humans have no enzyme to restore the C4-5 double bond once reduced, that's a permanent step.

DHB seems > 2x more anabolic than primbolan, and more so than testosterone. It also hasn't had any effect on my estrogen, same as primobolan.

And just because DHB is dihydroboldenone, that doesn't mean it is a substrate for human 5⍺ reductase - that reduction reaction may well only happen in a laboratory setting. My guess is there is minimal if any DHB produced from EQ in the body. So even though there is just one double bond distinguishing them, consider them as completely different compounds that can be used together.

Chemically I believe the Δ1-testosterone group deserves it own branch in the steroid family tree.

Boldenone
>c17 methylated = Dianabol
>5⍺-reduced = Dihydroboldenone
>>c1-methylated = Primbolan
>>c2-methylated = Stenbolone

c1 methyl group was added for (relatively) safe oral bioavailability of primobolan acetate. it also seems to impart partial resistance to 3⍺-HSD so is more anabolic in muscle than DHT.

c2 methyl group was added specifically to avoid breakdown by 3⍺-HSD. Given same food and training, in my experience masteron is a superior anabolic to primobolan - but traditionally masteron has been used in a cutting phase in a calorie deficit, while primobolan was used offseason in a calorie surplus. Most of the other androgens with high anabolic:androgenic ratios (meaning no potentiated 5⍺-reduced androgens) and resistance to 3⍺-HSD are also specifically modified at C2 - anadrol, anavar, winstrol, etc.

Only reasons I can think of why DHB might be more toxic than primbolan as an injectable AAS:

1. Lower solubility, propensity to form microcrystals (without full crashing) that are injected than irrirate/inflame the muscle, causing PIP and systemic inflammation.

2. Androgenic potency, this is why metribolone/mibolerone are so much more toxic than anadrol, wintrol, superdrol, dianabol, etc. All are c17-methylated AAS but only the ultra potent ones have to be taken in the mcg range.

3. Bad raws, from M1T contamination. This went from a mass marketed OTC product to illegal overnight, it is possible that some raws were reprocessed into DHB which could then be made into and sold as DHB oil. Seems unlikely, but it happened not that long ago to a major UGL and their stenbolone acetate - which was in fact methyl-stenbolone when tested. Btw I have some vials of that, and it makes one awesome androgen preworkout.

 

[Banana Joe]

.....
Chemically I believe the Δ1-testosterone group deserves it own branch in the steroid family tree.
...
a major UGL and their stenbolone acetate - which was in fact methyl-stenbolone when tested. Btw I have some vials of that, and it makes one awesome androgen preworkout.

Thanks for the writeup, it was quite interesting to read. I will need to read it a few more times though, to make sense of all this.
I had just expressed interest in Stenbolone by coincidence, and then figured I really need to try Methyl-Stenbolone. But I was not able to find a UGL that sells injectable M-Sten.

 

[Photon]

Thanks for the writeup, it was quite interesting to read. I will need to read it a few more times though, to make sense of all this.
I had just expressed interest in Stenbolone by coincidence, and then figured I really need to try Methyl-Stenbolone. But I was not able to find a UGL that sells injectable M-Sten.

There was a vendor who sold Stenbolene 100mg/ml last yr, but it was tested as Msten instead. Pity i did not pick up a few vials.

The only way now seems to be to buy the orals and brew it, I don't even think there's raws left for it.

 

[Banana Joe]

There was a vendor who sold Stenbolene 100mg/ml last yr, but it was tested as Msten instead. Pity i did not pick up a few vials.

The only way now seems to be to buy the orals and brew it, I don't even think there's raws left for it.

This damn steroid shortage makes me want steroids I would not have wanted otherwise. I am such a hoarder. 100mg/ml concentrations sounds great, the other orals you mostly get at 50mg or lower.

How do you brew from a pressed tablet? How do you separate the drug from the filler(-s) again?

 

[Photon]

This damn steroid shortage makes me want steroids I would not have wanted otherwise. I am such a hoarder. 100mg/ml concentrations sounds great, the other orals you mostly get at 50mg or lower.

How do you brew from a pressed tablet? How do you separate the drug from the filler(-s) again?

It depends on the filler in question.
Most vendors use fillers that do not dissolve in oil (hydrophilic), so you crush it, brew it oil/ba/bb and you just filter it out.

MCC is a very common filler, it swells in water, but does not dissolve in oil or water.

 

[IndividualMan]

wish I had pulled the trigger on SSA Msten.
sad

 

[Banana Joe]

wish I had pulled the trigger on SSA Msten.
sad

In honour of SSA I have just ordered 100*10mg tabs. Not sure if I am ever going to take them, but I am also a hoarder and collector, and currently suffer a lot from steroid FOMO, due to the recent shortage.

Because of this I also ordered a kit of DHB - just in case.

 

[adrenalytic]

Because of this I also ordered a kit of DHB

vials of pain. godspeed.