Chilton Labs - UK Domestic & International

Anyone using the 5mg semaglutide from Chilton? My wife started off on the 2mg ones at 0.25mg a week, moving up to 1mg. She switched over to the 5mg vials and is convinced it's not working now. My batch code is: CLSM02
 
Do all glp’s need to be watered down that much? I’ve been running 2ml in 50mg of tirz and running 0.1ml (2.5mg) with great success

Do you think pharma chooses the dilution rate based on some random number picked out of thin air?

If success is based on feels, sure, If success is measured by the amount of antibodies very slowly, incrementally, imperceptibly building up and chipping away at the efficacy of tirz over time, perhaps things aren't going as well as you think. Especially considering this is a class of drugs that offer the best benefits over extended use, if not for a lifetime.

Among other things, a more concentrated dose allows a greater proportion of the peptide to be transported to lymph nodes, where your immune system "studies" them for more effective removal in the future.

To most people, this may sound like "bubble boy" nonsense, but factors like these are why development of these drugs takes the better part of decade and billions of dollars. People's long term health and lives are at stake,
 
Do you think pharma chooses the dilution rate based on some random number picked out of thin air?

If success is based on feels, sure, If success is measured by the amount of antibodies very slowly, incrementally, imperceptibly building up and chipping away at the efficacy of tirz over time, perhaps things aren't going as well as you think. Especially considering this is a class of drugs that offer the best benefits over extended use, if not for a lifetime.

Among other things, a more concentrated dose allows a greater proportion of the peptide to be transported to lymph nodes, where your immune system "studies" them for more effective removal in the future.

To most people, this may sound like "bubble boy" nonsense, but factors like these are why development of these drugs takes the better part of decade and billions of dollars. People's long term health and lives are at stake,
My success was based off 50+lbs of weight loss lol. But that’s very interesting to know. Seems like selling 50mg in 3ml vials isn’t the smartest move by QSC then. I appreciate the info. I’ll water it down
 
My success was based off 50+lbs of weight loss lol. But that’s very interesting to know. Seems like selling 50mg in 3ml vials isn’t the smartest move by QSC then. I appreciate the info. I’ll water it down

What keeps peptide developers up at night are the handful of disasters that, while rare, have been catastrophic.

A lifesaving peptide treatment that was working well, slowly losing efficacy over
several years and the patient, with no alternative treatment available, dying.

Something as simple as a manufacturer slightly changing the manufacturing method of a syringe, using a tungsten pin to make a hole, leaving near atomic level traces of tungsten behind, causing the peptide to "aggregate", triggering an immune response that made the patient develop an immunity to certain endogenous proteins, resulting in them losing of the ability to produce red blood cell.

Perhaps the most well documented, most common of these rare events, are the instances of children who slowly develop antibodies to growth hormone, resulting in GH treatment failure, often after 2 or 3 years.

These kinds of hard to detect risks are managed by, among many other factors, ensuring the proper concentration is used.
 
My success was based off 50+lbs of weight loss lol. But that’s very interesting to know. Seems like selling 50mg in 3ml vials isn’t the smartest move by QSC then. I appreciate the info. I’ll water it down


FWIW, some UGLs haphazardly mix peptides, as if proteins don't interact, literally creating new Frankenstein drug molecules with unknown effects that have never been studied. Only recently a single
example, Sema and BPC being sold by compounding pharmacies was looked at closely, and found essentially turned the users of this concoction into unwitting guinea pigs.

IMG_0487.webp


"Testing of a compounded semaglutide drug product containing BPC-157 revealed that only parts of the secondary structure of the semaglutide chain overlapped with the semaglutide used in FDA-approved medicines. Specifically, an "overlay was observed from amino acid 7 to amino acid 20, whereas for the remaining part the signals of [the sample] had shifted" such that "the folding of semaglutide from amino acid 21 to amino acid 37 was different from the semaglutide in FDA-approved medicines.

The red circles mark differences in the NMR spectra between the semaglutide FDA-approved medicines and the product containing BPC-157. The black box shows the corresponding data mapped to the secondary structure of semaglutide."

OK, but it's obviously harmless. I mean plenty injected it, and I don't see reports of anyone "losing an ass cheek", so that change to the Semaglutide peptide chain caused by its interaction with BPC must not do anything important.

The report submitted to the FDA continues:

"This modification constitutes a critical impurity, which must be controlled in the final product."

"Critical impurity" is a very sterile term of biotechnology art that means exactly what the worst thing you might imagine it means.
 
FWIW, some UGLs haphazardly mix peptides, as if proteins don't interact, literally creating new Frankenstein drug molecules with unknown effects that have never been studied. Only recently a single
example, Sema and BPC being sold by compounding pharmacies was looked at closely, and found essentially turned the users of this concoction into unwitting guinea pigs.

View attachment 315883


"Testing of a compounded semaglutide drug product containing BPC-157 revealed that only parts of the secondary structure of the semaglutide chain overlapped with the semaglutide used in FDA-approved medicines. Specifically, an "overlay was observed from amino acid 7 to amino acid 20, whereas for the remaining part the signals of [the sample] had shifted" such that "the folding of semaglutide from amino acid 21 to amino acid 37 was different from the semaglutide in FDA-approved medicines.

The red circles mark differences in the NMR spectra between the semaglutide FDA-approved medicines and the product containing BPC-157. The black box shows the corresponding data mapped to the secondary structure of semaglutide."

OK, but it's obviously harmless. I mean plenty injected it, and I don't see reports of anyone "losing an ass cheek", so that change to the Semaglutide peptide chain caused by its interaction with BPC must not do anything important.

The report submitted to the FDA continues:

"This modification constitutes a critical impurity, which must be controlled in the final product."

"Critical impurity" is a very sterile term of biotechnology art that means exactly what the worst thing you might imagine it means.
Interesting. I imagine the same might apply to mixing separate peptides into the same syringe before pinning?
 
Interesting. I imagine the same might apply to mixing separate peptides into the same syringe before pinning?
Yes. And some react instantly. I drew some mots-c into a syringe of HGH and it turned to jizz in the syringe. Never mixing a peptide outside of bpc/tb500 and Ghk ever again
 
Price hike :eek:
Good. I said ages ago that this hommie needs to up his prices.

He’s been overwhelmed a number of times, and now he’s not taking on new customers. Clearly he’s swamped (or just doesn’t need the money as much lol).

If he ups the price, that makes things more available for those who are willing to pay.

His stuff is as quality as UGL can get, and the service is as good as it needs to be. It’s a premium product compared to most other vendors.

MAKE THE PRICES HIGHER :mad:
 
While I don’t want the prices to go any higher, it wouldn’t bother me if they did. For what I use Chilton for these days (500mg EQ and their primo when it becomes available) you can’t beat jerri for price, quality or service.
 
Good. I said ages ago that this hommie needs to up his prices.

He’s been overwhelmed a number of times, and now he’s not taking on new customers. Clearly he’s swamped (or just doesn’t need the money as much lol).

If he ups the price, that makes things more available for those who are willing to pay.

His stuff is as quality as UGL can get, and the service is as good as it needs to be. It’s a premium product compared to most other vendors.

MAKE THE PRICES HIGHER :mad:
While I understand your point, asking for price increases instead of capacity increases as a customer is not normal, I don't think there will be any difference in order amount as it's still competitive. There's little reason for anyone to look at other vendors.
 
asking for price increases instead of capacity increases as a customer is not normal
Of course increasing capacity would make the most sense. But Chilton Labs is supposedly ran by a sole man, who claims to run a solo operation for a good reason.

I don't think there will be any difference in order amount as it's still competitive. There's little reason for anyone to look at other vendors.
Then he may as well increase the price. From his perspective at least. If demand exceeds supply, up the price.

Maybe that’s what he’s doing by titrating the prices up over time. A sudden increase of 50% would piss people off. But 2.5% a month for 20 months would go down okay.

Either way, I want him to enjoy his luxurious lifestyle enough to keep selling us the good stuff. The moment he says “fuck this it’s not worth it anymore” I’ve gotta find someone else.

It sets a good example, too. Too many vendors sell products not tested with Jano, and with poor service. If the Chilton prices go up, it shows to everyone else that you can make more money by selling quality stuff and by having good service. It fits the ethos of “harm reduction”.
 
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