What was said, and what you clearly don’t understand is that early GH side effects are adaptation related and commonly disappear with continued exposure. That isn’t opinion, it’s basics.
Yea so 3 weeks of 2-3 IU s 8 months ago caused adapation to my body so now when I inject 6-8IU from the start I don't feel anything right, and this sound 100% like chatgpt wrote it lmao, "That isn't opinion, it's basics"
You had pronounced sides at 3 IU for 3 weeks from SSA because you were GH naive, you introduced an acute osmotic and IGF-1 shift, your body hadn’t adapted yet. That’s again basics.
And my body somehow remained adapted 8 months later of not using GH and now even if I pin 4x the dose I don't feel anything hmm ok, or you re gonna say I have antibodies now
Starting later at 6 to 8 IU and getting nothing does not automatically mean “bunk hgh.”
I didn't say it does, I said it's different
It means one of three things and this is where your lack of understanding shows. You have a process of physiological adaptation (most common)
Does your little brain comprehend what adaptation means? It shouldn't happen instantly, I didn't felt anything from the first 6IU dose then nothing from the subsequent 6 and 8 doses, or again you're saying the fact that I did GH for 3 weeks at a dose 3-4 times less means my body fully adapted to GH sides forever
different pharmacokinetics due to dosing, timing, or splitting,
And what exactly are those pharmacokinetics ? I take it at the same time, at a much bigger dosage
and quality issues that don’t present as classic GH sides.
Here’s the part you skipped entirely, prolonged or exaggerated GH sides are more often linked to BAD GH, not good GH.
Low-quality UGL GH can contain protein aggregation, residual host cell proteins, (really bad) endotoxin contamination, improper bond folding, or equally so dose inconsistency vial to vial.
ok let me quote you
I'm not arguing with you, but since you're arrogant. Nobody is discrediting anything you said.
Go do your intro post in the new member thread.
And stop posting if your not going to accept the responses. I don't care what your convinced by. This is the last I'm hello you with since your wanting to argue your feelings.
The classic early GH effects (carpal tunnel like numbness, hand tingling, edema) come from physiologic changes. Sodium & water retention (renal effect), GH increases:, Renal sodium reabsorption, Plasma volume, Interstitial fluid This temporarily raises pressure in confined spaces (carpal tunnel, wrists, fingers).
That’s why you get puffy hands, tight rings
Numb fingers at night. IGF-1 tissue swelling expands soft tissue.
This causes transient nerve compression
What you're referring to is adaptation stress.
Most people start GH at too high a dose or increase too fast. Your body hasn’t upregulated. So why those effects often DISAPPEAR....After 2 to 6 weeks your kidneys adapt to sodiu, pressure, and nerves stop being compressed. The same GH, same dose, no more sides...
This is well documented in clinical GH therapy. So your feelings mean shit. Get it tested or don't. I don't care what you do.
idiots like yourself argues one way then he finds out he proves my point argues the other way just so he can win the argument lmao
Those cause inflammation driven effects...So your logic of “no sides fake” is not just wrong, it’s backwards.
Right now you’re doing the classic beginner move confusing acute sensation with efficacy, then getting emotional when I challenged it.
If you want to argue science, learn it first.
If you want to argue feelings, TikTok is probably a better platform.
Arrogant bastard.
let's see what the chatgpt bot that you use and trained to just argue for you says about your statements
"It is a common misconception that "high-quality" pharmaceutical HGH shouldn't cause side effects. In reality, medical literature and clinical studies prove the exact opposite:
water retention is one of the most common and predictable physiological effects of real Somatropin, regardless of the brand's quality.
The argument that "side effects = bad quality" is medically incorrect. In fact, if someone takes a high dose of pharmaceutical HGH and feels
nothing (no joint tightness or slight water retention), it is often a sign the product is under-dosed or fake.
1. Does Pharma-Grade HGH Cause Water Retention?
Yes. Every major pharmaceutical brand (Norditropin, Genotropin, Humatrope, etc.) explicitly lists "peripheral edema" (swelling of the hands and feet) as a common side effect in their prescribing information.
- The Mechanism: HGH causes the kidneys to retain sodium and water by activating the renin-angiotensin-aldosterone system (RAAS) and the sodium-potassium pump. This is a direct biological action of the growth hormone molecule itself, not a result of "impurities."
- The "Purity" Myth: In the 1980s, early HGH derived from cadavers had impurities that caused issues. Modern recombinant (rhGH) is over 99% pure. The water retention you feel today is the hormone working on your kidneys, not your body reacting to "dirty" fillers.
2. What the Studies Show
Clinical data shows that side effects are
highly dose-dependent.
- Low Dose (0.5 – 2.0 IU/day): Often used for anti-aging or GH deficiency. At this level, water retention is usually mild or non-existent in healthy individuals.
- Moderate Dose (4.0 – 6.0 IU/day): Frequently used by athletes. Studies show a significant increase in Extracellular Water (ECW) at these levels. In one study of healthy young adults taking supraphysiological doses, extracellular water increased by nearly 10% within weeks.
- High Dose (8.0+ IU/day): At these levels, the incidence of side effects like "moon face" (facial edema), carpal tunnel syndrome (from fluid pressing on the wrist nerves), and joint pain becomes nearly universal.
3. Dosage and Side Effect Relationships
The relationship is a classic
dose-response curve: the higher the dose, the more severe the side effects.
Note on "Starting" Effects: Many users experience the worst water retention in the first 2–4 weeks as the body adjusts to the new sodium balance. Doctors typically start patients at very low doses (0.5 IU) and "titrate" up slowly to minimize these issues.
The "Sign of Quality": While extreme side effects aren't
desirable, the presence of mild water retention and carpal tunnel-like symptoms is actually a classic indicator that the HGH is biologically active."