Who here is on a statin?

[SmallTitsIRL]

If anyone is using a statin you use it all the time you don’t cycle off. Once you see the massive benefits in bloods you’d be an idiot to get off.

I get your point, but if on a cruise your LDL is 60 without a statin, why would you keep the statin in? That's my way of thought. Do not use drugs unnecessarily, this is my recommendation, not what I do to be precise.

 

[Billbo98]

I get your point, but if on a cruise your LDL is 60 without a statin, why would you keep the statin in? That's my way of thought. Do not use drugs unnecessarily, this is my recommendation, not what I do to be precise.

Most have an LDL of 60 only because of the use of a statin. My point being is we pump our bodies with bath tub brew regularly we shouldn’t be afraid of running a statin indefinitely. I get your point I’m just saying I wouldn’t say it applies to statins per se.

 

[SmallTitsIRL]

Most have an LDL of 60 only because of the use of a statin. My point being is we pump our bodies with bath tub brew regularly we shouldn’t be afraid of running a statin indefinitely. I get your point I’m just saying I wouldn’t say it applies to statins per se.

You do have a point there. Hmm and knowing that there's no lower-limit on LDL, running it during a cruise a cruise may actually be better long term. You're right.

 

[Manualtrt]

What studies show ie from large trials (like IMPROVE-IT, FOURIER, and others) consistently show:

• Every ~39 mg/dL (1 mmol/L) drop in LDL leads to a ~20–25% relative reduction in major CV events
• The benefit continues even below 70 mg/dL
• No clear “harm threshold” has been seen down to ~20–30 mg/dL in trials

So the difference between 60 and 40 for example ≈ 10–12% relative reduction in major cardiovascular events.

For me the risk return ratio is in the get ldl as low as possible camp