Who here is on a statin?

[the_pope]

If you only ever run a short 4-week oral and your baseline lipids are excellent, technically you could skip a statin. Your lipids will normalize after you stop.

BUT:
Each time you spend weeks with HDL near zero and LDL/ApoB elevated, you are accelerating vascular damage.

I’ve seen orals push HDL to single digits in 2-4 weeks, though not ss aggressive with LDL but they do increase LDL but it still takes a hit.

Only superdrol trashed my HDL to single digits in 4 weeks. Dbol is not that bad, but still, it reduces HDL and pushes LDL way up, last time to 190 while normally I'm below 100. The vascular damage worries me. I might buy some rosu to take while on dbol just in case. It can't hurt.

 

[Deadpool99]

ubiquinol is always worth it, just alone for the heart health and the mitrchondial function, ideally throwing in some PQQ as well

fuck me, I wanted to get 300mg minimum of ubiquinol (high quality extracted form Kaneka) 200mg capsules go for $36 for a month's supply (assuming I take 2 servings to get 300-400mg)

 

[Duke309]

fuck me, I wanted to get 300mg minimum of ubiquinol (high quality extracted form Kaneka) 200mg capsules go for $36 for a month's supply (assuming I take 2 servings to get 300-400mg)

I recommend QH-Absorb from Jarrow, it is pricey though.
You can wait for coupon codes from vita cost to be a big discount on a few bottles at a time.

 

[Bestganja]

I take 10mg Rosuvastatin M/W/F. No sides at all. LDL down by 30%

 

[Anonymous35]

Please help me. Muscle Safety? Drug Interactions? Feel great in it. Only 20mg.

Why don’t every doctor just describe the others if better? Price?

No habits, atorvastatin is the most prescribed, i do belive its also one of the first statin who came and he is pretty effective
But i prefer pravastatin, rosuvastatin i hated it

 

[Damaged1]

No habits, atorvastatin is the most prescribed, i do belive its also one of the first statin who came and he is pretty effective
But i prefer pravastatin, rosuvastatin i hated it

What’s the difference? I’m on resuvostatin, seems fine but I have nothing to compare it to.

 

[egruberman]

What’s the difference? I’m on resuvostatin, seems fine but I have nothing to compare it to.

Rosuvastatin is hydrophilic, doesn't cross the blood brain barrier and is more efficacious at lower doses than atorvastatin. Atorvastatin was the first "high intensity" statin and the thing that doctors tend to push.

I much prefer Rosuvastatin in lower doses in combination with other lipid lowering compounds. Theoretically, Rosuvastatin would have fewere adverse side effects than Atorvastatin, but the data don't show a lot of difference. There are reasons for this, not least of which is that most people on statins are on the max dose. Pravastatin is less efficacious than Rosuvastatin, but at equivalent doses, has fewer side effects.

 

[Damaged1]

Rosuvastatin is hydrophilic, doesn't cross the blood brain barrier and is more efficacious at lower doses than atorvastatin. Atorvastatin was the first "high intensity" statin and the thing that doctors tend to push.

I much prefer Rosuvastatin in lower doses in combination with other lipid lowering compounds. Theoretically, Rosuvastatin would have fewere adverse side effects than Atorvastatin, but the data don't show a lot of difference. There are reasons for this, not least of which is that most people on statins are on the max dose. Pravastatin is less efficacious than Rosuvastatin, but at equivalent doses, has fewer side effects.

Ok cool thank you.

I was on 5MG Ed off cycle and now on cycle I’m on 20 mg Ed.

 

[egruberman]

I was on 5MG Ed off cycle and now on cycle I’m on 20 mg Ed.

Yeah, I'd add other compounds before going above 10mg Rosuvastatin. The addition of ezetimibe and bempedoic acid will yield a greater reduction of LDL than that extra 10mg of Rosuvastatin. Like other statins, most of the efficacy comes at 25% of the max dose:

• 10 mg: ~46% LDL-C reduction
• 20 mg: ~50–52%
• 40 mg: ~55%

I've posted this a bunch, but of note is that all of them flat line in efficacy and increase in adverse side effects:

 

[Bammdk]

Yeah, I'd add other compounds before going above 10mg Rosuvastatin. The addition of ezetimibe and bempedoic acid will yield a greater reduction of LDL than that extra 10mg of Rosuvastatin. Like other statins, most of the efficacy comes at 25% of the max dose:

• 10 mg: ~46% LDL-C reduction
• 20 mg: ~50–52%
• 40 mg: ~55%

I've posted this a bunch, but of note is that all of them flat line in efficacy and increase in adverse side effects:

View attachment 351415

That is a usefull graph! Thanks!

 

[Anonymous35]

What’s the difference? I’m on resuvostatin, seems fine but I have nothing to compare it to.

Its great but for me (stage 5 kidney failure) i got rhabdo, one of the worse pain ever

 

[The Answ3r]

My labs back in early June on cycle looked pretty rough. As soon as I saw them, I cranked rosu from 5 mg up to 10 mg and added Bempesta EZ 10 mg. Then, because apparently I enjoy living dangerously, I tossed anavar in at 50 mg daily for 7 weeks, full YOLO mode.


Later on, once pita came in, I swapped it for rosu, started at 2 mg for a week and then moved up to 4 mg, while keeping Bempesta EZ rolling. Here are my labs now, honestly looking way better than I expected.


Big thanks to the guys who suggested Bempesta EZ, pretty sure @Photon was the first one who threw that out there. Guess I owe him a beer, or at least some cleaner lipid panels.

 

[egruberman]

Later on, once pita came in, I swapped it for rosu, started at 2 mg for a week and then moved up to 4 mg, while keeping Bempesta EZ rolling. Here are my labs now, honestly looking way better than I expected.

These are great results.

 

[longletter]

Atorvastatin here 20mg daily. Started beginning of year after cholesterol tests. Age late 50s.
Fasting gave 6.x. Religious improvement of sugar in diet got it down ranging 4.2 - 5.2 over a month of early morning tests.
No fears of diabetes, GP said I should consider a statin. "Keep your arteries supple" - he said something like that, I paraphrase.
No sides/issues with taking it. My perception is its a cheap prevention.
I stay concsious of the diet improvements too.

 

[Nixonnow99]

Yeah, I'd add other compounds before going above 10mg Rosuvastatin. The addition of ezetimibe and bempedoic acid will yield a greater reduction of LDL than that extra 10mg of Rosuvastatin. Like other statins, most of the efficacy comes at 25% of the max dose:

• 10 mg: ~46% LDL-C reduction
• 20 mg: ~50–52%
• 40 mg: ~55%

I've posted this a bunch, but of note is that all of them flat line in efficacy and increase in adverse side effects:

View attachment 351415

Would love to see one of these graphs with pitavastatin added.

 

[BamaCrazy]

Would love to see one of these graphs with pitavastatin added.

I think this has been posted before.

 

[Anonymous35]

I think this has been posted before.

View attachment 352331

What is Bemp ? Its safe on kidney dialysis?

 

[Nixonnow99]

What is Bemp ? Its safe on kidney dialysis?

Bempedoic acid. Quick google search says generally safe for mild to moderate kidney damage.

 

[RockyP]

Increased my primo to 400 mg (test up to 425) while increasing Pitavastatin to 4 mg. LDL still dropped another 10%, now under 60. Will be adding Zetia in the coming months. Being able to run nearly a gram of gear with DHT’s on board (and no side effects from the statin) and having an LDL this low is pretty tits

Full disclosure my HDL dropped 20% on this stack but with an LDL this low I really don’t care.

 

[Avies48]

Increased my primo to 400 mg (test up to 425) while increasing Pitavastatin to 4 mg. LDL still dropped another 10%, now under 60. Will be adding Zetia in the coming months. Being able to run nearly a gram of gear with DHT’s on board (and no side effects from the statin) and having an LDL this low is pretty tits

Full disclosure my HDL dropped 20% on this stack but with an LDL this low I really don’t care.

What are ur triglycerides?