Interesting. I started using nebiv to see if it nudge the rhr down but im also fairly stressed most days. Used small amounts of propranolol very rarely and it certainly does the job maybe even too much. Thanks for sharing
MESO-Rx
Anabolic Steroids
What is your current RHR?
- Thread starter Kralteramon
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Sicsemptyran
Member
Nebivolol sounds like it might be just the thing for you then. Because it doesn’t hit all beta receptors and cross the brain as much, it still lowers stress response but less aggressively in the brain. Propranolol, while amazingly effective, can sometimes feel like turning everything off (including drive, motivation, libido, etc).
Nebivolol just cuts it a bit.
Liter O' Test
Member
does nebivolol affect your HRV or "stress tracking"
Im about to test this soon on its own. Will update.
Sicsemptyran
Member
For most folks, all things being equal, it should. All things that increase sympathetic activity -> lower HRV, all things that lower sympathetic activity -> raise HRV.
Therefore things like beta blockers, clonidine, benzos, barbiturates, etc will all raise HRV. Stimulants (adderall/epinepherine/ephedrine/yohimbine), thyroid hormone, etc, will all lower HRV.
The only difference would be in magnitude of effect and baseline.
Liter O' Test
Member
im doing 1.25mg tomorrow , will see how it goes
TheBeast1
New Member
Looking forward to your report.
I am glad I found this thread. I've been doing 400mg NPP and 200mg test with 2mg of reta weekly. My RHR has been in the 90s at night and during the day hangs out around 100.
I've reduced the stims and recently discovered Ivabradine. Put in an order and that's going to take about 2-3 weeks to come in which sucks.
Overall though, I feel fine. I sleep fine. I have had other issues this blast with a stupid injury (my fault) and a weird asthma flair up that was caused by me switching from a mirv 13 to 8 filter during peak ragweed season. Went to an allergist and got a slew of drugs to address that.
When I did my first 500mg test blast, nebivolol took my RHR and pushed it into the 60s. This time around, it is not responding at all to the beta blocker which I suspect is because of the glp1 agonist. I took about 4 weeks off from the reta and while the RHR dropped steadily the nandrolone clearly is also keeping it up as well.
I do cardio weekly. Run about 7.5 minute miles for ten minutes 5 days a week. Planning on doing more by adjusting my work out schedule soon.
Regardless, glp1 agonists have absolutely wrecked my RHR. As much as I love them I wish I picked up Ivabradine much sooner. When I re-up with our friends abroad, I will be switching back to tirz and passing on reta for the foreseeable future which only gave me a modest bump. Unlike the reta which shot it up and never came back down.
Good write up. Hope the iva works for you. Keep us updated.
Its always a moving target especially when theres a number of variables...at least in my case i tend to layer too many things on. I've still not figured it out.
Eddie.
Member
I used to believe beta blockers don’t work for glp induced high rhr, with HGH and Reta I was in the 90s too.
After adding ivabradine it came down but mostly throughout the day. I was having mid 80s through sleep and i didn’t want that, so I said fck it and tried 5mg nebivolol on top.
Now my daytime rhr is low 70s and throughout sleep I’m seeing rhr even in the 60s. Works like a charm for me.
Sadly though, I believed it was going to help me with my shitty quality sleep but it doesn’t.
TheBeast1
New Member
Go figure after I spend 200$ on a bunch of drugs I decided to up my nebivolol to 5mg.
And now my RHR is staying in the 90s far more consistently even with effort. Curious saw a huge drop in blood pressure which was already done(120s/high 70s) into the 115/65 today.
I didn't split my reta dose like I normally do though so the efforts of the drug wearing off beyond the middle of the week can definitely be a thing.
Always is right? Our bodies can be so stubborn at times.
At least it's in a better range right now.
thegreatestalltime
New Member
60 is average for me.
TheBeast1
New Member
Update on this thread. I got my ivabradine as a Christmas present. I knew it was coming so I tapered off my nebivolol dose which I felt wasn't really doing anything.
Frankly glad I did. I don't like how beta blockers make my heart feel.
Started with 7.5mg at night and didn't see any improvement in my RHR or RHV the next day. I did note I felt more rested but that might have been placebo.
The standard medical advice for ivabradine is to take 7.5 twice a day (morning and night). I decided to go against this because of my poor HRV so the following night I took 15mg.
Wow, I had an immediate change in my RHR dropping from 92 to 90 and my HRV shot up from 16 to 23.
I was noticeably far more rested and running the next day was very easy for my 10 minutes. I wanted to go to 20 but decided against it because of house chores.
Same thing again last night 15mg at bedtime. HRV has improve again to 27 HRV and RHR is down to 88.
Since these are both computed by an algorithm I expect this to improve with each night I take the meds.
Notably I am sleeping a lot better now and clearly have some significant sleep debt I need to pay back from thrashing my body tired day over day and not realizing it.
Bonus point, my stubborn systolic blood pressure who was always in the low 130s/60s has dropped onto the 120s now. I wasn't expecting that.
I'm a huge fan of ivabradine over nebivolol now and when using nand I will work it into my stack when my RHR and hrv drop.
Frankly glad I did. I don't like how beta blockers make my heart feel.
Started with 7.5mg at night and didn't see any improvement in my RHR or RHV the next day. I did note I felt more rested but that might have been placebo.
The standard medical advice for ivabradine is to take 7.5 twice a day (morning and night). I decided to go against this because of my poor HRV so the following night I took 15mg.
Wow, I had an immediate change in my RHR dropping from 92 to 90 and my HRV shot up from 16 to 23.
I was noticeably far more rested and running the next day was very easy for my 10 minutes. I wanted to go to 20 but decided against it because of house chores.
Same thing again last night 15mg at bedtime. HRV has improve again to 27 HRV and RHR is down to 88.
Since these are both computed by an algorithm I expect this to improve with each night I take the meds.
Notably I am sleeping a lot better now and clearly have some significant sleep debt I need to pay back from thrashing my body tired day over day and not realizing it.
Bonus point, my stubborn systolic blood pressure who was always in the low 130s/60s has dropped onto the 120s now. I wasn't expecting that.
I'm a huge fan of ivabradine over nebivolol now and when using nand I will work it into my stack when my RHR and hrv drop.
You've inspired me to try this tonight.
Having messed around with both and not really seeing much. Definitely get a capped hr from nebiv with cardio which is expected.
When you say 'nand' are you referring to nandrolone?
I am taking a GLP-1 and getting shitty sleep. The interesting thing is my overnight HRV(mid 20s) on my Garmin watch is generally ok and sometimes it is unbalanced. My HRV in the AM, before I get up, is taken on Morpheus and the HRV is in the mid 60s. I do cardio 5-6 times a week for 25-30 minutes. I do drink coffee but I am done with two cups by 11AM and don't have any after.
Sicsemptyran
Member
Clearly you feel much better which can’t be discounted whatsoever, glad it’s working for you!
I am curious to hear how it is after a week or two because I will say, RHR from 92 -> 88 on face value doesn’t really seem like much to me. Good night sleep vs bad night sleep can be a 10bpm swing for me alone, and that’s ~45 -> ~55, so an even greater magnitude with a corresponding HRV change.
Again, you feeling a lot better and moving in the right direction is great/not discounting the effects though!
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