MESO-Rx
Anabolic Steroids
Tirzepatide raw
- Thread starter Kunu
- Start date
Deadp007
Member
...you'd have to lyophilize it first
(which is just a nerdy way of saying "freeze-dry" it).
(which is just a nerdy way of saying "freeze-dry" it).
Magnus0u812
New Member
I would be very cautious doing this. Having a sterile environment and process is a big deal.
maryslittlegoat
New Member
Why is lyophilization necessary to make it usable? Raw is completely unusable, correct?
Jire
Member
I think heat will rapidly degrade the compound (unlike what I think about AAS), so you must sterilize in a different manner. Peptides are so fragile even shaking the bottle can degrade them.
If it is not lyophilized it wont do it's job after injecting it.
This is a myth and most peptides are very stable even when shaked.
maryslittlegoat
New Member
Without lyophilizing peptides will not have the same effect after reconstituting? Can you please elaborate why? People that do not know or understand these things (like me) are wasting a lot of $ and maybe serious associated safety risks.
Focusing on why it won’t work over safety seems the best way to get some people to wake the F up and start asking questions.
It’s scaring me honesty what I’m reading people are blindly doing in other forums.
Focusing on why it won’t work over safety seems the best way to get some people to wake the F up and start asking questions.
It’s scaring me honesty what I’m reading people are blindly doing in other forums.
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Jire
Member
Where can I learn more about lyophilization, homebrewing peptides, or their stability?
clearheaded
Member
it will come already lyophilized obv, just will be in a vac bag vs vial. issue is u cant filter it like u can oils, and it won't keep like oils will. dont be cheap and just buy it pre vialed..
ie forget it no one home-brews peptides.... only reason to not get vialed GLP is if u are taking it orally. even then will be such a pain to work with to dose and keep 100% free from atm moisture
ie forget it no one home-brews peptides.... only reason to not get vialed GLP is if u are taking it orally. even then will be such a pain to work with to dose and keep 100% free from atm moisture
Deadp007
Member
Pretty sure it does not comes pre-lyophilized.
But at any rate, I think you'd need a sterile room, well beyond the scope of 99.99% of citizens.
Maybe if you had Elon Musk type of money.... but then, why bother...
But at any rate, I think you'd need a sterile room, well beyond the scope of 99.99% of citizens.
Maybe if you had Elon Musk type of money.... but then, why bother...
maryslittlegoat
New Member
There are China sources selling none lyophilized, non vacuumed vials of tirz. It is a thing. People are blindly buying it, reconstituting and injecting it.
No thank you. It is alarming.
No thank you. It is alarming.
I don't doubt this happens, along with all sorts of other alarming things. The question is how do we know who to trust. Sources testing everything prior to sale is all I can think of.
Example, I have a Chinese source selling 10mg Tirzepatide kits for $250
Do I take the chance? Haven't decided.
maryslittlegoat
New Member
So what’s ur understand why it has to be freeze dried? Sounds like its for shelf life for the stability of the peptide. Apparently there is ALSO something that it does so med delivers correctly in the system. Do you know what that is?
Ask if it is lyophilized. Ask if vacuum sealed. Ask if they have current labs. I bet they say no.
Ask if it is lyophilized. Ask if vacuum sealed. Ask if they have current labs. I bet they say no.
clearheaded
Member
nothing to do with delivery of meds and everything to do with making it stable. 100% dry aka lyophilized is essential for stability, and why all peptides are. few are far more stable lik ghk-cu but still will have been freeze dried.
maryslittlegoat
New Member
Got it, thank you. If a peptide is unstable what could happen?
Initial thought is amino chains comprising the peptide break apart easily without being stabilized? If correct, when reconstituted an unstable peptide is likely to have the amino chains break apart. Making the peptide essentially useless. That’s a total guess though.
I do understand getting lyophilized peptides is absolutely essential. I’m not questioning that, just trying to understand further.
clearheaded
Member
just ask QSC 
as likely can talk to there engineers and get a proper answer. I dont know, but armed with logic and some minor understanding.
my assumption is peptides degrade into there aminos and or variations of smaller chains ie smaller peptides. fold is another option re dimmer.
long and short of it is dont order bulk and attempt to home-brew peptides unless for topical application.
as likely can talk to there engineers and get a proper answer. I dont know, but armed with logic and some minor understanding.my assumption is peptides degrade into there aminos and or variations of smaller chains ie smaller peptides. fold is another option re dimmer.
long and short of it is dont order bulk and attempt to home-brew peptides unless for topical application.
buffaloindierock
New Member
1. You don't need to lyophilize it. You can use a 0.3 micrometer syringe to filter. Read up on the best syringes because you want to also minimize peptide adhesion when doing this. Just measure and mix your raws with BAC and then use the filter syringe to transfer to a sterile vial.
2. If you do want to lyophilize it, it's because you want to make it more stable and long-lasting for dry storage. You don't need to buy a machine. Lots of universities have chem programs where you can take a training course to pay and rent the lab/equipment...and/or they allow students/research assistants to do it (it generates revenue). Ask about a sanitization step during lyophilization (it's not automatic - not all lyophilization is sterile).
2. If you do want to lyophilize it, it's because you want to make it more stable and long-lasting for dry storage. You don't need to buy a machine. Lots of universities have chem programs where you can take a training course to pay and rent the lab/equipment...and/or they allow students/research assistants to do it (it generates revenue). Ask about a sanitization step during lyophilization (it's not automatic - not all lyophilization is sterile).
