I'd say start with the basics, Ubiquinol, PQQ, decent anti-oxidants, Choline & Inostiol, Reservatol, Quercetin. If you wanna go a bit more basic, NMN and 5Amino1MQ.
Then you can go a step higher bringing in MOTS-C, i go with 1mg a day together with 500mg of Carnitine with my pre-workout meal (injectable).
I recently also added Methelyne Blue which is supposed to have additional benefits for Mitochondria but i mostly use it because it gives me a good mental wellbeing overall and havent noticed anything else apart from that.
From there on you can throw in NAD+ things like Glutathione. If you look these up you can see that those are great anti-oxidants but also play a big role in mitochondrial function and recycling of those.
They all work really well together, can recommend reading up on the connection between NAD+, NMN, 5Amino1mq and NAC. Very interesting overall!
A bigger stack which i would always run during a cut and offseason would also include then SLU and SS-31.
As Mitochondrial health is impacted by so much, you could argue that during a cut where your body lacks calories, proper nutrition and is under a bit more stress than general, you want your mitochondria to function at 100% to really preserve muscle, energy and melt fat easier.
Vice versa for a off-season when you put your body under stress from additional weight, water, high carb intake, potential blood sugar issues and so on.
Obviously it's quite pricey but i personally just stick with the same amount of AAS, keep my mitochondrial health at a very high priority and control the rest by activity, cardio and food and never had a plateau or face a time where i felt like i made no progress.
And honestly, i really love how this improved glucose issues (chronically fucked Homa and also diabetic and this was the first time i saw major improvements in it and i did not use a SLGT2, GLP, Metformin or Thiazolidinediones). The positive change in lipids was a nice bonus on top.
Bit of Mitochondrial support, sprinkle in some Retra and trust me, your diet will bet easiest and smoothest you will ever have without having to crank up your AAS (at least in my personal experience).
