Skin Thread Over 40

[nathenking]

I run KLOW from Opti daily and hoping the same thing. For better skin. As I've gotten into my 40s my skin is getting more loose so trying to get out in front of that!

 

[deuces_00]

IMO, the entire stack which one would need to improve/prevent photoaging is simply:

basic skincare routine;
- cleansing am and pm
- moisturizing after cleansing
- spf in am and even applied again in afternoon if you please
- topical retinoid daily (tazarotene or tretinoin 1% are fantastic choices)
*ramp up the frequency in which you use the topical retinoid of choice and also start with a weaker concentration and graduate to higher concentration*

drugs;
- low dose isotretinoin (5 mg/day or 10 mg MWF)
- GH (HRT replacement dose is entirely sufficient for skincare purposes)
- GHK-cu 2-3 mg/day (not as researched as the other interventions but i think its promising and sure wont hurt)

Theres other compounds that I think are worthy additions such as glutathione/antioxidants but the above more than covers your bases.

I personally use basic cerave foaming facial cleanser am and pm, (i let my face airdry after cleansing because towels just trap bacteria) basic cetaphil moisturizer, and la roche posay SPF. 10 mg isotret MWF, tretinoin 0.1% every night, 3 mg GHK-cu per day, 375 mg glutathione MWF, and im going to be starting GH in the near future.

 

[aromatizer]

Anyone inject Ghk-cu? Been doing the glow combo but switching to just ghk for a month to avoid receptor issues. The ghk (from peptide sciences) is super dark blue and has had pip at 2.5mg sub a. Much lighter blue with bpc and tb500 also and no pip. Any workarounds?

been looking into this as glow gave me bad site reaction and I suspect GHK-CU will too. make what you will of this one I found, Anela protocol:

Ratio 50mg GHK-CU to 10mg BPC; if you have 100mg GHK-CU it's 20mg BPC

Bac needs to be 3mL per 50mg GHK-CU; if you have 100mg GHK-CU it's 6mL bac

Syringe 8mm (5/16") — too long of a needle can go too deep on research subject (RS) and it becomes intramuscular. The half-life of GHK-CU is too short to make a difference. GHK-CU has a short plasma half-life. So please be careful with this. Intramuscular is a faster/rapid release. We do not want that. The slower release, the better.

Are you using the Anela injection technique? Breaking up the 12 units (2mg GHK-CU) into 3 mini pins? This is a step most researchers miss and don't understand. Keep each pin under 5 units. This creates a slow release of GHK-CU, providing another layer for preventing the histamine response.

After the 3 mini pins (4 units, 4 units, 4 units), add percussion massager for 3 to 5 minutes on high. This should not be done for any other peptides.

Still not working? There are added measures for super responders. I am one of them.

Any leftover ISRs (injection site reactions), always keep a vial of BPC on hand. BPC is a mast cell stabilizer. It will help anytime you have an ISR. Citation here on BPC and mast cell stabilization.

, .

I do not mention it often as it's a bit of a bigger step. You will need to obtain Epi/Lido (epinephrine/lidocaine). Do not ask where to get here, please. We can't do that. IYKYK.

Conduct this advanced workaround in your lab at your own risk.

Substitute 1mL of epi/lido for bac during reconstituting (do NOT use lido alone: the epi is necessary).

So you have: 50/10/10 or 50/10/10/10 with:

1mL epi/lido
2mL bac
2mg GHK-CU pin and 400mcg BPC
Break up into 3 mini pins
Percussion massager 5 minutes

Haven't tried it yet, lidocaine I can find but epinephrine with or without lidocaine requires a prescription.

 

[heavydutygorilla]

been looking into this as glow gave me bad site reaction and I suspect GHK-CU will too. make what you will of this one I found, Anela protocol:



Haven't tried it yet, lidocaine I can find but epinephrine with or without lidocaine requires a prescription.

I had horrible reaction from KLOW blend myself. Wife, no problems. I believe some of us don't do well with what's happening between all of those peptides in the blend. I ordered KPV, GHK-CU, BPC157 and TB500, can run all independently just fine with no issues or reactions. I actually have noticed an improvement in my skin health/fine lines/healing from cuts since implementing the ghk-cu. On my second 100mg vial now.

 

[deuces_00]

I had horrible reaction from KLOW blend myself. Wife, no problems. I believe some of us don't do well with what's happening between all of those peptides in the blend. I ordered KPV, GHK-CU, BPC157 and TB500, can run all independently just fine with no issues or reactions. I actually have noticed an improvement in my skin health/fine lines/healing from cuts since implementing the ghk-cu. On my second 100mg vial now

I also suspect PIP is exacerbated when the GHK is in a blend. I experienced PIP with pinning GLOW for the first few days then haven’t experienced anything since - with the blend or with GHK solo

 

[Ricardovrol]

Does anyone has experience with accutane and an already dry skin as a result of a damaged skin barrier?

 

[adrenalytic]

Does anyone has experience with accutane and an already dry skin as a result of a damaged skin barrier?

I have mild eczema and am using tretinoin with accutane. I don't see dryness anywhere else but my face. Aquaphor and Eucerin keep things bearable.