Semaglutide for weight loss in Hashimoto's – Need advice for my partner

[Hacksquatter]

HI everyone,

I’m writing to ask for advice regarding my partner. She’s 30 years old, 159 cm tall, and weighs 88 kg. She has Hashimoto’s thyroiditis but her thyroid levels are currently compensated according to her endocrinologist, so she’s not on levothyroxine.

She follows a structured diet and exercises regularly, but despite all her efforts, she’s unable to lose weight. She also suffers from cervical discopathy and osteoarthritis, which limit her physical activity to some extent.

She’s interested in trying semaglutide for weight loss and reached out to her doctor, but hasn’t received a response yet – possibly because they’re reluctant to prescribe it.

Given her situation – Hashimoto’s (compensated), difficulty losing weight despite lifestyle changes, joint issues – do you think she could be a good candidate for semaglutide?

Thanks in advance for your help.

Daniel

 

[Ghoul]

HI everyone,

I’m writing to ask for advice regarding my partner. She’s 30 years old, 159 cm tall, and weighs 88 kg. She has Hashimoto’s thyroiditis but her thyroid levels are currently compensated according to her endocrinologist, so she’s not on levothyroxine.

She follows a structured diet and exercises regularly, but despite all her efforts, she’s unable to lose weight. She also suffers from cervical discopathy and osteoarthritis, which limit her physical activity to some extent.

She’s interested in trying semaglutide for weight loss and reached out to her doctor, but hasn’t received a response yet – possibly because they’re reluctant to prescribe it.

Given her situation – Hashimoto’s (compensated), difficulty losing weight despite lifestyle changes, joint issues – do you think she could be a good candidate for semaglutide?

Thanks in advance for your help.

Daniel

Yes, though Tirzapatide appears to lower inflammation to a greater degree than Semaglutide, which will help relieve osteoarthritis symptoms.

GLPs are prescribed to people with Hashimoto's, there are no contraindications preventing it. The only recommendation is that thyroid levels be monitored (they will change with weight loss and improved metabolic markers), which she's already having done anyway,

Given her conditions I think it's very likely she'll see a significant improvement in health and quality of life after a few months, from the weight loss and reduced systemic inflammation.

The first months are the most challenging, but reassure her there's a point at which unpleasant side effects stop altogether, and the benefits continue long term.

 

[Hacksquatter]

Thank you so much for your reply. The main difficulty here in Italy is actually getting a prescription—despite having a well-documented clinical situation, many doctors are still very reluctant to prescribe GLP-1s.

We’re trying to find a way, maybe through a more up-to-date endocrinologist, but it’s not easy.

I really appreciate the support and the information!

 

[Ghoul]

Thank you so much for your reply. The main difficulty here in Italy is actually getting a prescription—despite having a well-documented clinical situation, many doctors are still very reluctant to prescribe GLP-1s.

We’re trying to find a way, maybe through a more up-to-date endocrinologist, but it’s not easy.

I really appreciate the support and the information!

No worries. To be clear, Semaglutide is very effective as well, so don't hesitate if that's the only option available.

Also, if pharma isn't possible, consider buying it from an underground. source here.

 

[Hacksquatter]

Thanks. I honestly don’t know how to order it in Italy, and I’m not familiar at all with the underground scene. Is there any guide or thread on the forum that explains how it works or how to get started safely?

 

[Ghoul]

Thanks. I honestly don’t know how to order it in Italy, and I’m not familiar at all with the underground scene. Is there any guide or thread on the forum that explains how it works or how to get started safely?

Unfortunately we can't discuss underground sources outside of the underground forum, and you can't post there until you're more active (posting comments, and reacting to posts.

You're also too new to be given access to direct messages.

However, you can read posts in the underground forum.

So all I can advise at the moment, is go to the underground forum, look at the threads of various suppliers, such as Sigma Audley, SRY, HYB, Semaglutide and Tirz are very inexpensive. You'll find their contact information on the first post. Almost everyone ships to Italy.

Email them and ask for a price list and how to order.

It's not terribly difficult. If you need help with crypto currency, there's a forum here for those questions you can post in with your current permissions.

For help on how to use these products, post your questions here in the weight loss forum.

 

[Hacksquatter]

Unfortunately we can't discuss underground sources outside of the underground forum, and you can't post there until you're more active (posting comments, and reacting to posts.

You're also too new to be given access to direct messages.

However, you can read posts in the underground forum.

So all I can advise at the moment, is go to the underground forum, look at the threads of various suppliers, such as Sigma Audley, SRY, HYB, Semaglutide and Tirz are very inexpensive. You'll find their contact information on the first post. Almost everyone ships to Italy.

Email them and ask for a price list and how to order.

It's not terribly difficult. If you need help with crypto currency, there's a forum here for those questions you can post in with your current permissions.

For help on how to use these products, post your questions here in the weight loss forum.

Thank you very much, I’ll do that. I still need to get more familiar with Bitcoin, but I’ll read the posts and learn. Thanks again!

 

[Superchicken]

My mom is using low dose tirz and has had an improvement in arthritic joint pain. She also has Hashimoto’s. There is some research on glp1’s reducing inflammation and helping autoimmune diseases.

As far as the compensated Hashi’s, I’d try to find a different dr. Endo’s are notorious for treating only tsh and don’t care if you’re symptomatic. Sometimes a low dose medication alleviates symptoms, but it can take seeing several drs before you find a good one. If you find a dr who prescribes natural desiccated thyroid (ndt) or liothyronine, they’re usually more willing to explore treatment.

Lastly, I know you said your wife is 30, which is a few years early for falling into perimenopausal age, but I’d have her hormones checked by a specialist. Thyroid dysfunction is common mid 30s amongst women, and so is osteoarthritis and other health conditions due to declining hormones. It’s been awhile since I’ve looked, but I believe there was a link with low testosterone and earlier diagnosis of OA in women. Worth looking into jic. I’d recommend checking ferritin and vitamin d as both are directly tied to thyroid health and are often deficient. Dr Vonda Wright is an orthopedic specialist in the USA who published a paper last year on the musculoskeletal syndrome of menopause. She’s active on instagram and has it pinned on her page.

 

[Hacksquatter]

My mom is using low dose tirz and has had an improvement in arthritic joint pain. She also has Hashimoto’s. There is some research on glp1’s reducing inflammation and helping autoimmune diseases.

As far as the compensated Hashi’s, I’d try to find a different dr. Endo’s are notorious for treating only tsh and don’t care if you’re symptomatic. Sometimes a low dose medication alleviates symptoms, but it can take seeing several drs before you find a good one. If you find a dr who prescribes natural desiccated thyroid (ndt) or liothyronine, they’re usually more willing to explore treatment.

Lastly, I know you said your wife is 30, which is a few years early for falling into perimenopausal age, but I’d have her hormones checked by a specialist. Thyroid dysfunction is common mid 30s amongst women, and so is osteoarthritis and other health conditions due to declining hormones. It’s been awhile since I’ve looked, but I believe there was a link with low testosterone and earlier diagnosis of OA in women. Worth looking into jic. I’d recommend checking ferritin and vitamin d as both are directly tied to thyroid health and are often deficient. Dr Vonda Wright is an orthopedic specialist in the USA who published a paper last year on the musculoskeletal syndrome of menopause. She’s active on instagram and has it pinned on her page.

Thank you so much for your reply. It’s truly appreciated. Your answer is very professional and of high caliber — thoughtful, insightful, and far from obvious. You gave me a lot to think about and look into. I really appreciate you taking the time to share your knowledge and experience.

 

[Nemesis RR]

What is her TSH level? Do you know if her thyroid levels are good? I went through hell with my wife being told her levels were good when they weren’t.

 

[HeatherSwanson]

What's the effect of sea kelp or iodine? Has she tried for thyroid issue

 

[Here2Learn]

I personally had much more inflammation regulation with Sema than Tirz, the relief was pretty significant for me.

 

[birdland]

What is her TSH level? Do you know if her thyroid levels are good? I went through hell with my wife being told her levels were good when they weren’t.

This. I'm so sick of this obsession with glp. What is her free t4, t3, tsh, antibodies? She should be on legit thyroid medication to get her thyroid numbers in range in addition to proper diet (cico, no procecessed junk) and physical activity. If thyroid levels are in range she will have more energy subconsciously move more and burn more calories. Unless she can't put down the fork, which doesn't seem the case, she doesn't need medication that is designed for obese people who can not help but eat garbage.

GLP’s are a substitute for willpower not a miracle drug.