Rotating Compounds

[ItCantBe]

I know we all have our favorite compounds, and in an ideal world we could run the same stack and doses every cycle to equal or comparable results, but our bodies are generally masters of adaptation so we need to counter those effects.

I wanted to start a thread here to discuss rotating compounds between cycles. The pros and cons, personal experiences and preferences, anecdotal reports, hopefully we can have some forum veterans chime in and share their wisdom.

For example, I know I have a high affinity for aromatization so id love to be able to run 1:1 ratio of Test:Mast to help alleviate that but over time it seems to lose its effectiveness, especially when run repeatedly. If you were in my shoes, how would you rotate compounds to maintain effectiveness, counter aromatization, and maintain optimal/efficient growth?

 

[sliderke]

Gonna read along here. Never too old to learn.

 

[Slowww]

I don’t think it loses effectiveness at all… think you are probably just doing something wrong and blaming the drugs. You can run the same compounds 6 months and keep growing. 8 months too… you can run it 2023 and then 2024 and now exactly the same and still grow. eventually you have to add gear but the gear keeps working. I totally disagree with what you’re saying.

I’ve been using the same compounds for the last 3 bulks and with the most recent one using the same compounds put on 18lbs after cutting. It allows me to strictly compare my progress using the same compounds and dosages so I know that I am actually growing not just bloating up because PEDs are basically the same and stable.

The reason I rotate is one stack will be for off season where I don’t mind more water accumulating, and one stack for cutting where I want minimal water and lower estrogen to see how much muscle has been built minus the bloat. I rotate also to give a break from EQ, and also to have trt phase after tren use to make sure blood is perfect for growing after a cut.

Rotating compounds for me has nothing to do with compounds not working. They all work. It has to do with health outcomes, and goals which would be better addressed by different compounds.

 

[Flathead Fred]

Not that I’d necessarily recommend this but as I’ve gotten older(58) the compounds that I’ve run for years have started to turn from friend to foe. I’ve tried and ran them all and had great success with the exception of tren, go figure.

Now I’ll run EQ at 300/wk with Test 200/wk for 3 months. Around the 3 month mark the EQ anxiety sets in and I exchange it with Mast E at 200/wk and keep the Test at 200/ wk for 2 more months. I get the cardio benefits, strength and the veiny look I’m after with the EQ then the Mast E strips any water I may be carrying over from the EQ. This is a summer cycle, the other 7 months I’m back down to Test only at 200/wk.

I respond well to lower doses thankfully so my health markers don’t change much. HCT will creep up to the threshold until I yank the EQ and my LDLs as well but once I drop back to TRT levels everything returns to baseline.

Not sure if this was the “rotation” example you were looking for but it’s been working for me the last few years and I’ll continue until my body decides otherwise.

 

[Eddie.]

I don't think your body adapts because if that was true guys who run a steady dose of test for their TRT would face severe issues after a while and that's not happening.

You might get used to the positive effects but that's a different story from drugs stop working or change their pharmacokinetics. For example, when you start using sildenafil for boners even at 25mg you feel hard as a rock. That stimulation goes away and you always seek more prominent effects. The drug doesn't stop working, you just want more of it. First time you'll give a 10mg cialis to someone walks around with weird boners, next thing everyone here is on daily cialis and everyone can control it perfectly.

There are plenty of pros who run Test and Primo for example all year round for their 2 main anabolics. Some may add NPP for the off season and tren for the prep but test/primo combo is either on bulking or cutting. The theory that androgen receptors downregulate is just a myth.

 

[Mastedon]

I'm relatively new new to using anything other than test and only tried a few compounds so I'll be in the phase of trying new ones for a while, figuring out what I like and don't like. My plan was to find the ones I like then use one set of multiple compounds at low doses for one lean bulk per year and another set for a cut each year. Now that you've brought this up I wonder if I might have to switch up compounds year to year. Probably nothing I need to worry about for years but I like that you brought up this interesting subject!