Reta phase 3 results out

[RockyP]

https://www.fiercebiotech.com/biotech/eli-lillys-obesity-triple-threat-smashes-efficacy-expectations-phase-3-proves-intolerable

I’m waiting for commentary from @Ghoul @Photon and others. They ratcheted these poor bastards up to 12 mg daily. Can’t imagine taking that much. Efficacy was above expectations but so was discontinuation rate (again, 12 mg is nuts).

Lilly has 7 more Reta trials in the works.

 

[chrzrd23]

Cagri also sucks metabolically. Who decided that a calcitonin agonist was a good idea? Let’s suppress both insulin and growth hormone at the same time!

Vig steve and his nonsense

 

[setters]

Cagrilintide SUCKS. That's why. You want to buy the rest of mine? I got no appetite suppression with 8mg reta until I was up to 1mg cagrilintide per week. But the cagrilintide made me feel like complete shit. It would suppress appetite for the first 3-4 days but I would feel like garbage with my head hurting constantly. Didn't want to do anything. Overall just down and yuck feeling. Not as bad as DNP lethargy but not far off. No thanks. I'll just add this is only my experience. Some people actually like cagrilintide.

Literally the worst, it's like getting hit by a bus