Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

You do not know shyte about Sub saharan africa. You watched some pictures of starving kids and think You're seen everything :D

Oh yeah bud he was way off-base with that one, wasn't he? Nobody is starving in sub-saharan africa. Everybody knows that. I hear they can all get 2,000 calories on every street corner, any time of day. The reason nobody is obese is because they are all incredibly disciplined.
 
You do not know shyte about Sub saharan africa. You watched some pictures of starving kids and think You've seen everything :D
Oh sorry man I didn’t know your from there, my bad. Does the lack of vegetation mess with the latency or what?

Jesus, the education system failed you. A simple use of the most common search engine would suffice to give you a simple overview on famines.
 
Oh sorry man I didn’t know your from there, my bad. Does the lack of vegetation mess with the latency or what?

Jesus, the education system failed you. A simple use of the most common search engine would suffice to give you a simple overview on famines.
It's the same way they tell many folks that Americans are stupid. I mean A simple search of reddit and Meso would confirm that no?
Anyway, I'm not here to educate folks about obesity, geography or nutritional epidemiology. Most peeps here are cooked solid. Whether its ideology, ignorance, half knowledge or sound research, it's too late. Let's just keep on sourcing whatever we're sourcing.
 
Oh yeah bud he was way off-base with that one, wasn't he? Nobody is starving in sub-saharan africa. Everybody knows that. I hear they can all get 2,000 calories on every street corner, any time of day. The reason nobody is obese is because they are all incredibly disciplined.
There is a massive line between take people to sub saharan africa and folks in sub-Saharan africa are starving. There are not a few places in sub Saharan africa that are facing rising obesity epidemic too. I can tell you it is not primarily due to burgers or high fructose corn syrup. A lot of food is rich in carbs and oil. Even for some nomadic tribes in east africa, over subsistence on milk and blood coupled with governments cutting off pastoral grazing lands means they're getting fatter too. Sub-Saharan africa is 2.5X as big as the USA. So I'm pretty sure the same thing happens all over. They even have a single climate :D
This could head downhill real fast so I'll rest before Millard brings out the chastisement birch.
 
There is a massive line between take people to sub saharan africa and folks in sub-Saharan africa are starving. There are not a few places in sub Saharan africa that are facing rising obesity epidemic too. I can tell you it is not primarily due to burgers or high fructose corn syrup. A lot of food is rich in carbs and oil. Even for some nomadic tribes in east africa, over subsistence on milk and blood coupled with governments cutting off pastoral grazing lands means they're getting fatter too. Sub-Saharan africa is 2.5X as big as the USA. So I'm pretty sure the same thing happens all over. They even have a single climate :D
This could head downhill real fast so I'll rest before Millard brings out the chastisement birch.
Just to clarify since everyone missed the point of my query. I don’t care where and who is starving or what they are eating, I am saying that basically you would need excess food to have excess bodyfat. It is a basic system, no need to go to the scientific explanations or mechanisms.

I am merely pointing out that even if you have the medical condition where you produce insane amounts of ghrelin if you do not have access to food, will you still get fat?

I don’t know how a simple question veered off drastically.

In addition, there are obese people where there’s famine and starvation because these guys are still eating more than they are burning unless there is a new law of thermodynamics that only apply to them.
 
connor tryin to break up the heat. The hero we need but don't deserve.

Just to clarify since everyone missed the point of my query. I don’t care where and who is starving or what they are eating, I am saying that basically you would need excess food to have excess bodyfat. It is a basic system, no need to go to the scientific explanations or mechanisms.

I am merely pointing out that even if you have the medical condition where you produce insane amounts of ghrelin if you do not have access to food, will you still get fat?

I don’t know how a simple question veered off drastically.

In addition, there are obese people where there’s famine and starvation because these guys are still eating more than they are burning unless there is a new law of thermodynamics that only apply to them.
This particularly kills me when my colleagues or friends try to explain their weight(gain) to me. All sorts of explanations from "starvation mode" and messed up thyroid. We aren't slaves in a camp where yes down regulation of bodily functions will indeed induce a "starvation mode", moreover how the hell are you in starvation mode when you're 300lbs plus?!? Either I'm missing something or people are not honest or aware of their food intake.

Yeah I mostly ranting into the air.

I can't let connor be the only guy to try and cool it down here.

inb4 connor blows up my inbox with questions
 
Just to clarify since everyone missed the point of my query. I don’t care where and who is starving or what they are eating, I am saying that basically you would need excess food to have excess bodyfat. It is a basic system, no need to go to the scientific explanations or mechanisms.

I am merely pointing out that even if you have the medical condition where you produce insane amounts of ghrelin if you do not have access to food, will you still get fat?

I don’t know how a simple question veered off drastically.

In addition, there are obese people where there’s famine and starvation because these guys are still eating more than they are burning unless there is a new law of thermodynamics that only apply to them.
Comparing extremes of malnutrition to explain obesity and the difficulty of getting off gained weight or the tendency to pack on weight is overly simplistic.
We know that there cannot be excess weight in a period of prolonged severe calorie deficiency. It does not mean that after weight is gained for a prolonged period, that some metabolic dysfunction doesn't occur. It is easy to say eat less, but if you have trashed your metabolism, there is limited ability for will power to work. Starvation is not a viable solution either. It is very very hard to physically starve yourself. You either need to be physically restrained, or the food absent (lookup starvation experiments like the one in Minnesota).
You can mess up your metabolism so bad that you start gaining weight on 2000 cals a day. I know someone who cut down to 1800 cals and kept gaining weight. The body just switches off as many things as it wants to preserve and reset weight. A Person just start sleeping more, develops exercise intolerance, is driven mad by thoughts of food. Starts taking caffeine ad all just to stay awake. Eventually dude lost his job from constant brain fog and "perceived laziness".. Well GLPs are helping with that metabolic reset now, to counter the body trying to reset to the abnormal pattern it is used to. There is a lot of research in this field and Knowledge keeps changing. Whether it is the cholesterol kills peeps were fed for ages that led to folks avoiding eggs, to retracted doctrines (7 nations study comes to mind) to even understanding situations like the "obesity paradox", there's a lot to malnutrition (over and under) that there is to be learned.

Nobody here has the time and patience for that. It's easier to say "ha ha ha Put down the cheese cake".. Just like they told folks back in the day to simply "say no to drugs".

Excuse the TLDR garbage... It's just an interesting field and a lot of unsponsored research is happening right before our very eyes.
 
Oh yeah bud he was way off-base with that one, wasn't he? Nobody is starving in sub-saharan africa. Everybody knows that. I hear they can all get 2,000 calories on every street corner, any time of day. The reason nobody is obese is because they are all incredibly disciplined.
It doesn’t take a rocket scientist to infer I was talking about “us” as in people in developed contries talking on internet devices about drugs on a forum.

I’d bet no none here faces daily famine and struggles to obtain 2000 calories in a day.

How about this- prove me wrong, ban you and @Ghoul ? If not I wil take a ban. Y’all interested? Show me a starving 3 world country member here with proof.

If not then shut up
 
is there an opposite drug to glps that would increase appetite
MK677 , a ghrelin mimetic. Works very well. Ghrelin is also a hormone. Makes you very hungry.

That’s been my issue until late 20’s- I had to really discipline my self to eat enough to pack on mass. It’s not easy. I’ll admit hands down cutting is harder though. @Ghoul isn’t wrong that being hungry sucks but it’s just apart of the process. You’re going to be hungry while you cut. Simple.
 
Lmao why the hate, I am merely stating the obvious fact that you cannot become fat without access to food geez. Get off your high horse mr. Natural but frequents a steroid forum.

If I say I am on trt prescribed by my urologist would that make my life longer and not diving to my death?

I don’t care why people use glp1s, ive used it too what I am asking is can you become fat without the necessary fuel to gain weight ie. excess food? Where in brazil or mexico are people starving and fat show me.
Yes, you are correct. An alcoholic needs accesss to alcohol, a drug addict needs access to drugs, an AAS addict (aka me) needs access to steroids…. It has hit the 3rd world now, too……

From the Cleveland Clinic:

“Worldwide, obesity has nearly tripled in the last 50 years. The rise has been especially dramatic in lower-income countries where malnutrition is common. These communities now have greater access to higher-calorie foods with low nutritional value. Obesity now commonly coexists with undernutrition in these countries.”

Science vs bro science……

“CDC considers obesity a complex disease that occurs when a person's weight is higher than what is considered healthy for their height. The National Institutes of Health (NIH) declared obesity a disease in 1998, and in 2013, the American Medical Association (AMA) House of Delegates voted to recognize it as a disease state that requires treatment and prevention.”

I am amazed at the amount of misinformation being preached at a place that is about education and harm reduction.
 
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ORD was specifically possible due to the Olympics being in China the following year. It gave the U.S. DEA some leverage to insist the Chinese government allow them to pursue their investigations within China. With that being said, it’s highly unlikely at this point that the Chinese government would allow the U.S. law enforcement in again.

That period of time was also fresh off the heals of the BALCO scandal, and GWBush was still in office (you know, former President of the Texas Rangers baseball team, the sport that happened to be immersed in that scandal.) it’s not the same now.

Lastly, with all the fentanyl and designer molly drugs that originate in China, it’s hard to believe at this point that the DEA would again waste that much resources to bust a bunch of gym rats, but you never know. Me personally I can’t really think of any reason to believe anything like ORD is in the works. It’s far more likely that eventually customs gets better at finding packs and that becomes a big problem, but where there’s a will, there’s a way and it just makes the cat and mouse game a little more complicated.

Edit: also as someone that went though gear grinder and raw deal etc etc etc, I am stunned at the amount of open domestic sourcing that happens anymore. I think those guys are fucking nuts and probably don’t understand the risks they are taking but who am I to judge? I wish them the best of luck but I really do get a deep concern in the pit of my stomach when I see it. That is low hanging fruit for law enforcement especially when it’s via the mail and across state lines. Again, those sources are fucking nuts (stupid) in my opinion. I had my own run in with the DEA when ORD went down and I wasn’t even a source. After ORD nobody wanted to be open on the internet all the domestic guys left, if they made it out, went private. A lot of them didn’t make it and ended up going fed prison time and having a bunch of their shit confiscated. To see domestic guys being open again now almost 20 years later tells me these guys either aren’t old enough or weren’t around back then and don’t understand what it is they are actually doing.
I was right there with you on your edit section. Most think there isn't gonna be a rainy day in this biz when you are a source. Well not me I knew a storm would happen one day. I didnt buy all the glamerous shit and show off. I created a life for the aftermath of the storm before the storm hit. Boy did it hit. Oh well made it through and life is so much less stressful now. Looking back on it I can't believe I even did what I did. Its when things get so quiet like it has been for years that a big bust will pop up. Its gonna happen its just when. These weight lose drugs will be very close to the top of the list. Big Pharma doesnt like money taken outa there pockets...
 
@Ghoul
Are you telling me all the people utilizing glp drugs have been tested and show low levels of glucagon??

You said:
'For those with normal glucagon levels, and a normal appetite, it's easy to point to an obese person and blame it on "willpower".'...
So your saying all these people that have an addiction to bad food (blame it on estrogen bc desire to eat salty or sugary food increases with higher estrogen... Or blame it on the dopamine response and raised endorphins from eating sugar)
Basically it's bout more chewing and swallowing or less but if it's more bout digestion and obtaining nutrients then ok)
But theres this :
'The term “gut microbiome” refers to the microorganisms living in your intestines. Each person has about 200 different speciesTrusted Source of bacteria, viruses, and fungi in their digestive tract.'
So complex eh
BTW I truly don't care bout the fat people thing... Just confusing bc if could eat more easily I'd keep upping my weight,(oh shit... If I chose to eat trash all the time I could prolly gorge more easily)
 
is there an opposite drug to glps that would increase appetite
Hey bud! Do me a favor and look up the mechanism of action (moa) on the glp drugs and look for things that do the opposite in regards to making foods desirable
I've tried using Actapro:
'Actapro Tablet is used in the treatment of functional dyspepsia. It helps to relieve the symptoms like bloating after a meal, pain/discomfort in the upper abdomen and early satiety (feeling of fullness in a short span of time after having only little food).'
And:
'What is the mechanism of action of acotiamide?
Acotiamide exerts its gastroprokinetic activity via presynaptic M1 and M2 muscarinic receptor inhibition, resulting in enhanced acetylcholine (Ach) release, and via inhibition of AchE activity in the stomach [42–45].Sep 11, 2015'
it'll definitely make you sit on the toilet but not sure how effective it is at increasing hunger.
Id appreciate a lil effort on your part to do some research (otherwise continue on with your random questions that only spur on more questions instead of leading to a breakthrough that you can actually contribute some other than to appease whatever people in your life as are saying that your social interaction)
'fish don't just jump on the boat' (quote heard Tom Brady reference) = you seem like a guy asking if gonna be able to eat anytime soon while asking questions bout fishing the whole time not trying himself
ok my bad everyone
 
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