Rosconow
Member
Yes, no, maybe.
MESO-Rx
Anabolic Steroids
Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic
- Thread starter Qingdao Sigma Chemicals
- Start date
BaldZues
Member
Aromasin is pretty accurate at 10mg per orange spoon leveled maybe a tad more than 10mg i wanna say when i weighed it, it ended up being 10.3 mg this is off the top of my head get yourself a scale before you take my word. A scale would be the safest route someone may be paking a bunch tampered down leveled but still weigh more than heaping spponful. Its all in how you pack down the spoon, leveled, heaping, most important is weight by a scale its much more accurate than someone telling you how much each spoon weighs for my packed level may weigh more than someones loose heaping
Something to note, would be interested in anyone's opinion who has obtained a semi-relevant academic degree. A French company named Gattefossé manufactures a variety of solvents (and other excipients) for drugs. Two that look super interesting are "Transcutol HP"[0] (oral, nasal, ophthalmic) and "Transcutol P"[1] (dermal).
One study[2] finds that isotretinoin has a solubility of ~19mg/mL as an oral preparation in Transcutol HP (dependent on temperature). Another study[3] found isotretinoin has a solubility of ~50mg/mL in Transcutol P. Note, Transcutol is *very* lipophilic and hydrophobic.
Is there a good reason we couldn't use Transcutol to dissolve a month's worth of isotretinoin and administer it daily orally in 1mL/1tsp volumes? Obviously it would have to be kept in the dark or the isotretinoin will decompose immediately and thoroughly due to light (especially UV - left in sunlight isotretinoin fully decomposes in <4 hours).
0: Transcutol® HP
1: Transcutol® P
2: Solubilization and Thermodynamic Analysis of Isotretinoin in Eleven Different Green Solvents at Different Temperatures
3: https://downloads.hindawi.coo/archive/2013/108569.pdf
Also @Qingdao Sigma Chemicals , is there any chance you might be able to look into helping to distribute Transcutol HP/P to us? They might be useful for a variety of preparations that are normally difficult to dose but I don't think any of us "individuals" will be able to buy from the manufacturer or distributors.
One study[2] finds that isotretinoin has a solubility of ~19mg/mL as an oral preparation in Transcutol HP (dependent on temperature). Another study[3] found isotretinoin has a solubility of ~50mg/mL in Transcutol P. Note, Transcutol is *very* lipophilic and hydrophobic.
Is there a good reason we couldn't use Transcutol to dissolve a month's worth of isotretinoin and administer it daily orally in 1mL/1tsp volumes? Obviously it would have to be kept in the dark or the isotretinoin will decompose immediately and thoroughly due to light (especially UV - left in sunlight isotretinoin fully decomposes in <4 hours).
0: Transcutol® HP
1: Transcutol® P
2: Solubilization and Thermodynamic Analysis of Isotretinoin in Eleven Different Green Solvents at Different Temperatures
3: https://downloads.hindawi.coo/archive/2013/108569.pdf
Also @Qingdao Sigma Chemicals , is there any chance you might be able to look into helping to distribute Transcutol HP/P to us? They might be useful for a variety of preparations that are normally difficult to dose but I don't think any of us "individuals" will be able to buy from the manufacturer or distributors.
Still available?
Ran out of time to edit.
I see
Prostaglandine (PGE1) - MOQ 5mg - $65
Phentolamine Mesilate - MOQ 100g - $200
but no Papaverine.
Also *NOT* that it particularly matters but a single dose of trimix is around Papaverine 3mg/Phentolamine 0.1mg/Prostaglandin 1 mcg
So your MOQ's are:
5000 doses of PGE1
1 million doses of Phentolamine
Even for a very large, potentially dangerous, dose of 50 units instead of 10 units, you're looking at 200,000 doses of Phentolamine. I don't think customers will ever use that much phentolamine! If there's any chance you could reduce the MOQ of phentolamine... ;-)
Also P.S. for other readers here I'm scared for anyone who attempts to measure out 50-100micrograms of prostaglandin for a single 10mL vial
Even if your scale has a resolution of 0.1mg doesn't mean it can measure a 5mg MOQ. This is because it has a "minimum weight". For 0.1mg scales that's usually at least 10mg. For 1mg scales its usually at least 20mg. If you try to measure less than that it's basically just a random number.So let's say you have a 1mg scale and you think you can get away with measuring 20mg so you buy 4 MOQ's of prostaglandin. The solubility of prostaglandin in water is about 1mg/mL so you can dissolve it in 20mL of water. But you need to reduce it to 5micrograms per mL. So you'll want to add 4 liters of water to that 20mL.
Then you can take out just 40mL of that 4L, then add 20mg (good luck again) of Phentolamine to it.
Then take 10mL of that 40mL and put it in a vial and add 150mg of Papaverine to that vial.
Now you've got 10mL = 100 doses of trimix.
aaaand you have 3.96L of water containing $259.35 of prostaglandin. Just go ahead and throw that away. Also throw out the 30mL of water containing Phentolamine+Prostaglandin. You won't need that either. You're also left with 99.98g of Phentolamine raw powder left over that you paid $199.60 for that you can throw out as well.
So, basically no matter what you do, you'll end up with 100-1000 doses of trimix and throw out >99% of your raws (>$400 thrown away). Is it worth it? Well, prescription Tri-mix is around $140/10mL vial. So if you make 4 vials, for 400 doses....I guess you technically save $150 + a doctors consultation fee. Also you have minimum 2 years worth of trimix (can't use it more than once EOD) and I dont know if it lasts that long in water! (and there really isn't a way to make it without water / some kind of true solvent...please dont even try without using a solvent to dilute, you'll definitely get your dick removed in the Emergency Room if you try to just work with dry powder raws at the microgram scale, even using geometric dilution...the particle sizes are not uniform and there will be clumping/separation/sorting rather than mixing)
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Boy... Just buy a fucking calibrated 10g weight and put it on the scale, then the powder. It will accurately work even for minimal stuff like 5mg. So much drama for nothing.Ran out of time to edit.
I see
Prostaglandine (PGE1) - MOQ 5mg - $65
Phentolamine Mesilate - MOQ 100g - $200
but no Papaverine.
Also *NOT* that it particularly matters but a single dose of trimix is around Papaverine 3mg/Phentolamine 0.1mg/Prostaglandin 1 mcg
So your MOQ's are:
5000 doses of PGE1
1 million doses of Phentolamine
Even for a very large, potentially dangerous, dose of 50 units instead of 10 units, you're looking at 200,000 doses of Phentolamine. I don't think customers will ever use that much phentolamine! If there's any chance you could reduce the MOQ of phentolamine... ;-)
Also P.S. for other readers here I'm scared for anyone who attempts to measure out 50-100micrograms of prostaglandin for a single 10mL vial
So let's say you have a 1mg scale and you think you can get away with measuring 20mg so you buy 4 MOQ's of prostaglandin. The solubility of prostaglandin in water is about 1mg/mL so you can dissolve it in 20mL of water. But you need to reduce it to 5micrograms per mL. So you'll want to add 4 liters of water to that 20mL.
Then you can take out just 40mL of that 4L, then add 20mg (good luck again) of Phentolamine to it.
Then take 10mL of that 40mL and put it in a vial and add 150mg of Papaverine to that vial.
Now you've got 10mL = 100 doses of trimix.
aaaand you have 3.96L of water containing $259.35 of prostaglandin. Just go ahead and throw that away. Also throw out the 30mL of water containing Phentolamine+Prostaglandin. You won't need that either. You're also left with 99.98g of Phentolamine raw powder left over that you paid $199.60 for that you can throw out as well.
So, basically no matter what you do, you'll end up with 100-1000 doses of trimix and throw out >99% of your raws (>$400 thrown away). Is it worth it? Well, prescription Tri-mix is around $140/10mL vial. So if you make 4 vials, for 400 doses....I guess you technically save $150 + a doctors consultation fee. Also you have minimum 2 years worth of trimix (can't use it more than once EOD) and I dont know if it lasts that long in water! (and there really isn't a way to make it without water / some kind of true solvent...please dont even try without using a solvent to dilute, you'll definitely get your dick removed in the Emergency Room if you try to just work with dry powder raws at the microgram scale, even using geometric dilution...the particle sizes are not uniform and there will be clumping/separation/sorting rather than mixing)
What scale are you personally using? I'll buy the exact same model and test it with a 10g calibration weight and a 5mg calibration weight and post photos.
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@Qingdao Sigma Chemicals I Know I asked thru email but a time frame on when hcg will be back instock usa warehouse? TY
nighthawkmuscle
Member
Is primo being shipped yet?
BrunoES
Member
considering brewing some Mast E at 300mg/ml with GSO/1.5% BA/18% BB. anyone done something similar?
Zoidberg
Subscriber
Most of the Masteron enanthate sold is either 200mg/ml or 250mg/ml. I brewed in MCT at 250mg/ml and it's holding perfectly. I think it's worth trying at 300.
Yes. Very doable
I might have miss it but… something happen with your proton mail? I tried emailing you this morning
BrunoES
Member
thanks for the input guys, appreciate it. I will give it a go and let people around here know later on.
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PushPullPl8s
New Member
Just a aws mg scale and a calibrated weight would work sufficiently?
Your not preventing problems your spreading baseless conspiracy theories and bullshit. Fuck off and shut the fuck up already.
Toni72
New Member
you are a lawyer and a judge, it only works for the disabled in your family, you can continue to spread your inability to think, it's going well, man
No I'm a Man with low tolerance for lies and bullshit which is all you have to offer. I'm done responding to you, learn to differentiate between reality and conspiracy old man.
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