Primal Pharma Test E 45mg EoD (TRT)

BigGulp

New Member
Test numbers came back in the low 300's the last two years during annual bloodwork. Technically within range so doc wouldn't prescribe test. Started self-managed TRT with Primal Pharma's Test E, 45mg eod, at the beginning of October.

New bloodwork came in and these are the new numbers, tested at trough. Much better but E2 was low which is strange. By all accounts I should be an high aromatizer at 30+%bf. No AI. Only thing it might be is 10mg tadalafil 3x week.
 

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Test numbers came back in the low 300's the last two years during annual bloodwork. Technically within range so doc wouldn't prescribe test. Started self-managed TRT with Primal Pharma's Test E, 45mg eod, at the beginning of October.

New bloodwork came in and these are the new numbers, tested at trough. Much better but E2 was low which is strange. By all accounts I should be an high aromatizer at 30+%bf. No AI. Only thing it might be is 10mg tadalafil 3x week.
Is this normal for you? I was reading that some people have a genetic predisposition that causes their estrogen receptors to be less sensitive. Yes, tadalafil can lower e2 levels as well.
 
Is this normal for you? I was reading that some people have a genetic predisposition that causes their estrogen receptors to be less sensitive. Yes, tadalafil can lower e2 levels as well.
Honestly, no idea. First time I've ever had estrogen checked. It'll be interesting to see what future tests measure.
 
Test numbers came back in the low 300's the last two years during annual bloodwork. Technically within range so doc wouldn't prescribe test. Started self-managed TRT with Primal Pharma's Test E, 45mg eod, at the beginning of October.

New bloodwork came in and these are the new numbers, tested at trough. Much better but E2 was low which is strange. By all accounts I should be an high aromatizer at 30+%bf. No AI. Only thing it might be is 10mg tadalafil 3x week.
What's your shbg and dht?

You are taking ~160mg a week but total test is only in 900's

So where's it going?

You probably didn't see an estradiol spike because you also don't have a testosterone spike
 
What's your shbg and dht?

You are taking ~160mg a week but total test is only in 900's

So where's it going?

You probably didn't see an estradiol spike because you also don't have a testosterone spike
Shbg: no clue
DHT: no clue
I'll make sure they're included in the next bloods.
Elektrobot shaming all us noobs into learning...

Sans numbers, I guess we can presume too much conversion to DHT not allowing for as much aromatization? Or high SHBG locking up test? What are the possibilities here? Willing to learn....
 
Steroid plotter shows I'm right about where I should be on total test with that dose. Just a little concerned about the low estrogen. No symptoms other than stiff joints but after carrying around all that weight, that's no surprise, especially in this cold.

No ir and no liver issues... Only med I was taking was tadalafil 10mg/eod to keep BP in check.

Injecting subq eod.

At this point, I'm just going to defer to next bloodwork results, get that Crp and calcium score, should have echo done by then. Then formulate next steps.
 
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